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Title: | DNA Sensors with Diamond as a Promising Alternative Transducer Material | Authors: | VERMEEREN, Veronique WENMACKERS, Sylvia WAGNER, Patrick MICHIELS, Luc |
Issue Date: | 2009 | Publisher: | MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL-MDPI | Source: | SENSORS, 9(7). p. 5600-5636 | Abstract: | Bio-electronics is a scientific field coupling the achievements in biology with electronics to obtain higher sensitivity, specificity and speed. Biosensors have played a pivotal role, and many have become established in the clinical and scientific world. They need to be sensitive, specific, fast and cheap. Electrochemical biosensors are most frequently cited in literature, often in the context of DNA sensing and mutation analysis. However, many popular electrochemical transduction materials, such as silicon, are susceptible to hydrolysis, leading to loss of bioreceptor molecules from the surface. Hence, increased attention has been shifted towards diamond, which surpasses silicon on many levels. | Notes: | [Vermeeren, Veronique; Wenmackers, Sylvia; Wagner, Patrick; Michiels, Luc] Hasselt Univ, Sch Life Sci, Biomed Res Inst, B-3590 Diepenbeek, Belgium. [Vermeeren, Veronique; Wenmackers, Sylvia; Wagner, Patrick; Michiels, Luc] Transnat Univ Limburg, B-3590 Diepenbeek, Belgium. | Keywords: | DNA; single nucleotide mismatch; aptamers; bioconjugates; biosensors; impedance sensors; SPR; fluorescence sensors | Document URI: | http://hdl.handle.net/1942/10853 | e-ISSN: | 1424-8220 | DOI: | 10.3390/s90705600 | ISI #: | 000268317000032 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2010 |
Appears in Collections: | Research publications |
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