Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/11711
Title: Kinetics of maternal antibodies against rubella and varicella in infants
Authors: Leuridan, Elke
HENS, Niel 
Hutse, Veronik
AERTS, Marc 
Van Damme, Pierre
Issue Date: 2010
Publisher: Elsevier
Source: VACCINE, 29(11). p. 2222-2226
Abstract: Kinetics of maternal rubella and varicella antibodies in 213 mother-infant pairs are described in a longitudinal study in Belgium. Blood samples are taken at 7 time points (week 36 of pregnancy, birth (cord), 1, 3, 6, 9, and 12 months), and analyzed for anti-rubella IgG and anti-varicella IgG by enzyme linked immunosorbent assay (ELISA). A generalised exponential model is used to analyse maternal antibody decay in infants. Model based, the mean duration of passive immunity is 2.1 months for rubella and 2.4 months for varicella. Infants are susceptible at young age for rubella, a disease with high vaccination coverage, as well as for varicella, an endemic disease in western Europe.
Keywords: Maternal Antibodies, Rubella, Varicella, Vaccination
Document URI: http://hdl.handle.net/1942/11711
ISSN: 0264-410X
e-ISSN: 1873-2518
DOI: 10.1016/j.vaccine.2010.06.004
ISI #: 000288731000033
Category: A1
Type: Journal Contribution
Validations: ecoom 2012
Appears in Collections:Research publications

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