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http://hdl.handle.net/1942/12304| Title: | Invasive fungal infection in an elderly patient with defective inflammatory macrophage function | Authors: | Chai, L. Y. A. Naesens, R. Khoo, A. L. Abeele, M. V. VAN RENTERGHEM, Koenraad Cartuyvels, R. Netea, M. G. GYSSENS, Inge |
Issue Date: | 2011 | Publisher: | WILEY-BLACKWELL | Source: | CLINICAL MICROBIOLOGY AND INFECTION, 17 (10). p. 1546-1549 | Abstract: | Macrophages are known to be involved in pathogen recognition and mediate host immune responses, but, in the clinical setting, their purported central role in opportunistic fungal infections has not been demonstrated to date. Herein, we describe a patient with invasive testicular aspergillosis in whom we found, for the first time, a defect in macrophage function. | Notes: | [Gyssens, IC] Jessa Hosp, Dept Infect Dis, B-3500 Hasselt, Belgium. [Gyssens, IC] Hasselt Univ, Diepenbeek, Belgium. [Gyssens, IC] Canisius Wilhelmina Hosp, Dept Med Microbiol, Nijmegen, Netherlands. [Chai, LYA; Khoo, AL; Netea, MG; Gyssens, IC] Radboud Univ Nijmegen, Dept Med, Med Ctr, NL-6525 ED Nijmegen, Netherlands. [Chai, LYA; Khoo, AL; Netea, MG; Gyssens, IC] Nijmegen Inst Infect Inflammat & Immun N4i, Nijmegen, Netherlands. [Chai, LYA] Natl Univ Hlth Syst, Univ Med Cluster, Div Infect Dis, Singapore, Singapore. [Naesens, R; Cartuyvels, R] Jessa Hosp, Lab Med Microbiol, B-3500 Hasselt, Belgium. [Abeele, MV] Jessa Hosp, Dept Geriatr Med, B-3500 Hasselt, Belgium. [van Renterghem, K] Jessa Hosp, Dept Urol, B-3500 Hasselt, Belgium. i.gyssens@aig.umcn.nl | Keywords: | Aspergillosis; innate immunity; postoperative;Aspergillosis; innate immunity; postoperative | Document URI: | http://hdl.handle.net/1942/12304 | ISSN: | 1198-743X | e-ISSN: | 1469-0691 | DOI: | 10.1111/j.1469-0691.2011.03598.x | ISI #: | 000295086100018 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2012 |
| Appears in Collections: | Research publications |
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