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Title: | Analysing the composition of outpatient antibiotic use: a tutorial on compositional data analysis | Authors: | FAES, Christel MOLENBERGHS, Geert HENS, Niel Muller, Arno Goossens, Herman Coenen, Samuel |
Issue Date: | 2011 | Publisher: | OXFORD UNIV PRESS | Source: | JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 66(S6), p. VI89-VI94 | Abstract: | In this tutorial, statistical methods for studying outpatient use of antibiotics in Europe are described, using data provided by IMS Health. The methods are applied to two related research questions, namely the assessment of changes in the relative volume of use of different antibiotic subclasses over time and changes in the absolute volume of antibiotic use. | Notes: | [Faes, Christel; Molenberghs, Geert; Hens, Niel] Univ Hasselt, Interuniv Inst Biostat & Stat Bioinformat I BIOST, Hasselt, Belgium. [Molenberghs, Geert] Catholic Univ Louvain, Interuniv Inst Biostat & Stat Bioinformat I BIOST, B-3000 Louvain, Belgium. [Hens, Niel] Univ Antwerp, CHERMID, Vaccine & Infect Dis Inst VAXINFECTIO, B-2020 Antwerp, Belgium. [Muller, Arno; Goossens, Herman; Coenen, Samuel] Univ Antwerp, Lab Med Microbiol, Vaccine & Infect Dis Inst VAXINFECTIO, B-2020 Antwerp, Belgium. [Coenen, Samuel] Univ Antwerp, Ctr Gen Practice, Vaccine & Infect Dis Inst VAXINFECTIO, B-2020 Antwerp, Belgium. christel.faes@uhasselt.be | Keywords: | log-ratio analysis; multivariate data; staying-in-the-simplex analysis; ambulatory care; Europe;log-ratio analysis; multivariate data; staying-in-the-simplex analysis; ambulatory care; Europe | Document URI: | http://hdl.handle.net/1942/12917 | ISSN: | 0305-7453 | e-ISSN: | 1460-2091 | DOI: | 10.1093/jac/dkr461 | ISI #: | 000297228400010 | Rights: | Copyright © 2017 British Society for Antimicrobial Chemotherapy | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2012 |
Appears in Collections: | Research publications |
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