Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/12917
Title: Analysing the composition of outpatient antibiotic use: a tutorial on compositional data analysis
Authors: FAES, Christel 
MOLENBERGHS, Geert 
HENS, Niel 
Muller, Arno
Goossens, Herman
Coenen, Samuel
Issue Date: 2011
Publisher: OXFORD UNIV PRESS
Source: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 66(S6), p. VI89-VI94
Abstract: In this tutorial, statistical methods for studying outpatient use of antibiotics in Europe are described, using data provided by IMS Health. The methods are applied to two related research questions, namely the assessment of changes in the relative volume of use of different antibiotic subclasses over time and changes in the absolute volume of antibiotic use.
Notes: [Faes, Christel; Molenberghs, Geert; Hens, Niel] Univ Hasselt, Interuniv Inst Biostat & Stat Bioinformat I BIOST, Hasselt, Belgium. [Molenberghs, Geert] Catholic Univ Louvain, Interuniv Inst Biostat & Stat Bioinformat I BIOST, B-3000 Louvain, Belgium. [Hens, Niel] Univ Antwerp, CHERMID, Vaccine & Infect Dis Inst VAXINFECTIO, B-2020 Antwerp, Belgium. [Muller, Arno; Goossens, Herman; Coenen, Samuel] Univ Antwerp, Lab Med Microbiol, Vaccine & Infect Dis Inst VAXINFECTIO, B-2020 Antwerp, Belgium. [Coenen, Samuel] Univ Antwerp, Ctr Gen Practice, Vaccine & Infect Dis Inst VAXINFECTIO, B-2020 Antwerp, Belgium. christel.faes@uhasselt.be
Keywords: log-ratio analysis; multivariate data; staying-in-the-simplex analysis; ambulatory care; Europe;log-ratio analysis; multivariate data; staying-in-the-simplex analysis; ambulatory care; Europe
Document URI: http://hdl.handle.net/1942/12917
ISSN: 0305-7453
e-ISSN: 1460-2091
DOI: 10.1093/jac/dkr461
ISI #: 000297228400010
Rights: Copyright © 2017 British Society for Antimicrobial Chemotherapy
Category: A1
Type: Journal Contribution
Validations: ecoom 2012
Appears in Collections:Research publications

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