Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/13125
Title: Antibiotic policy
Authors: GYSSENS, Inge 
Issue Date: 2011
Publisher: ELSEVIER SCIENCE BV
Source: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 38, p. 11-20
Abstract: There is a clear association between antibiotic use and resistance both on individual and population levels. In the European Union, countries with large antibiotic consumption have higher resistance rates. Antibiotic resistance leads to failed treatments, prolonged hospitalisations, increased costs and deaths. With few new antibiotics in the Research & Development pipeline, prudent antibiotic use is the only option to delay the development of resistance. Antibiotic policy consists of prescribing strategies to optimise the indication, selection, dosing, route of administration, duration and timing of antibiotic therapy to maximise clinical cure or prevention of infection whilst limiting the unintended consequences of antibiotic use, including toxicity and selection of resistant microorganisms. A secondary goal is to reduce healthcare costs without adversely affecting the quality of care. The purpose of this paper is to provide the evidence base of prudent antibiotic policy. Special emphasis is placed on urinary tract infections. The value and support of antibiotic committees, guidelines, ID consultants and/or antimicrobial stewardship teams to prolong the efficacy of available antibiotics will be discussed. (C) 2011 Elsevier B. V. and the International Society of Chemotherapy. All rights reserved.
Notes: [Gyssens, Inge C.] Radboud Univ Nijmegen, Med Ctr, Nijmegen Inst Infect Inflammat & Immun N4i, NL-6525 ED Nijmegen, Netherlands. [Gyssens, Inge C.] Radboud Univ Nijmegen, Med Ctr, Dept Med, NL-6525 ED Nijmegen, Netherlands. [Gyssens, Inge C.] Canisius Wilhelmina Hosp, Dept Med Microbiol & Infect Dis, Nijmegen, Netherlands. [Gyssens, Inge C.] Hasselt Univ, Diepenbeek, Belgium.
Keywords: Antibiotic policy; Antimicrobial stewardship; Antimicrobial resistance; Guidelines; Pharmacokinetics; Pharmacodynamics; Urinary tract infections;Infectious Diseases; Microbiology; Pharmacology & Pharmacy; Antibiotic policy; Antimicrobial stewardship; Antimicrobial resistance; Guidelines; Pharmacokinetics; Pharmacodynamics; Urinary tract infections
Document URI: http://hdl.handle.net/1942/13125
ISSN: 0924-8579
e-ISSN: 1872-7913
DOI: 10.1016/j.ijantimicag.2011.09.002
ISI #: 000298141200003
Category: A1
Type: Journal Contribution
Validations: ecoom 2013
Appears in Collections:Research publications

Files in This Item:
File Description SizeFormat 
gyssens1.pdf
  Restricted Access
article587.08 kBAdobe PDFView/Open    Request a copy
Show full item record

SCOPUSTM   
Citations

31
checked on Sep 7, 2020

WEB OF SCIENCETM
Citations

33
checked on May 13, 2022

Page view(s)

10
checked on May 19, 2022

Download(s)

6
checked on May 19, 2022

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.