Please use this identifier to cite or link to this item:
Title: Cell therapy in neonatal hypoxic ischemic encephalopathy
Authors: De Munter, Stephanie
Advisors: KRAMER, Boris W.
Issue Date: 2012
Publisher: tUL Diepenbeek
Abstract: Perinatal hypoxic-ischemic encephalopathy (HIE) is a major cause of preterm brain injury. In the Western world, there has been a tremendous increase in preterm birth rates over the past 20 years and the incidence of perinatal HIE is estimated at two to six per 1000 live-born infants. Currently, few treatment options are available for preterms suffering from HIE. In this translational research project, we hypothesize that Mesenchymal Stem Cells (MSC) and Granulocyte-Colony Stimulating Factor (G-CSF) therapies can reduce hypoxic-ischemic related synapse loss, neurodegeneration, microglial proliferation and damage to pre-oligodendrocytes in a fetal sheep model, thereby limiting preterm HIE.
Notes: master in de biomedische wetenschappen-klinische moleculaire wetenschappen
Document URI:
Category: T2
Type: Theses and Dissertations
Appears in Collections:Master theses

Files in This Item:
File Description SizeFormat 
08265992011249.pdf4.14 MBAdobe PDFView/Open
Show full item record

Page view(s)

checked on May 20, 2022


checked on May 20, 2022

Google ScholarTM


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.