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http://hdl.handle.net/1942/14310| Title: | The Prevention and Treatment of Missing Data in Clinical Trials | Authors: | Little, Roderick J. D'Agostino, Ralph Cohen, Michael L. Dickersin, Kay Emerson, Scott S. Farrar, John T. Frangakis, Constantine Hogan, Joseph W. MOLENBERGHS, Geert Murphy, Susan A. Neaton, James D. Rotnitzky, Andrea Scharfstein, Daniel Shih, Weichung J. Siegel, Jay P. Stern, Hal |
Issue Date: | 2012 | Publisher: | MASSACHUSETTS MEDICAL SOC | Source: | NEW ENGLAND JOURNAL OF MEDICINE, 367 (14), p. 1355-1360 | Abstract: | Missing data in clinical trials can have a major effect on the validity of the inferences that can be drawn from the trial. This article reviews methods for preventing missing data and, failing that, dealing with data that are missing. | Notes: | [Little, Roderick J.] Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA. [Murphy, Susan A.] Univ Michigan, Dept Stat, Ann Arbor, MI 48109 USA. [D'Agostino, Ralph] Boston Univ, Dept Math & Stat, Boston, MA 02215 USA. [Cohen, Michael L.] Natl Res Council Natl Acad, Washington, DC USA. [Dickersin, Kay] Johns Hopkins Univ, Dept Epidemiol, Baltimore, MD USA. [Frangakis, Constantine; Scharfstein, Daniel] Johns Hopkins Univ, Dept Biostat, Baltimore, MD 21205 USA. [Emerson, Scott S.] Univ Washington, Dept Biostat, Seattle, WA 98195 USA. [Farrar, John T.] Univ Penn, Sch Med, Dept Biostat & Epidemiol, Philadelphia, PA 19104 USA. [Hogan, Joseph W.] Brown Univ, Ctr Stat Sci, Program Publ Hlth, Providence, RI 02912 USA. [Molenberghs, Geert] Univ Hasselt, Int Inst Biostat & Stat Bioinformat, Louvain, Belgium. [Molenberghs, Geert] Katholieke Univ Leuven, Louvain, Belgium. [Neaton, James D.] Univ Minnesota, Sch Publ Hlth, Minneapolis, MN USA. [Rotnitzky, Andrea] Univ Torcuato Di Tella, Dept Econ, Buenos Aires, DF, Argentina. [Shih, Weichung J.] Univ Med & Dent New Jersey, Sch Publ Hlth, Dept Biostat, New Brunswick, NJ USA. [Siegel, Jay P.] Johnson & Johnson Consumer Prod Inc, Radnor, PA USA. [Stern, Hal] Univ Calif Irvine, Dept Stat, Irvine, CA USA. | Keywords: | Medicine, General & Internal | Document URI: | http://hdl.handle.net/1942/14310 | ISSN: | 0028-4793 | e-ISSN: | 1533-4406 | DOI: | 10.1056/NEJMsr1203730 | ISI #: | 000309406100016 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2013 |
| Appears in Collections: | Research publications |
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| File | Description | Size | Format | |
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| nejmrev2fin-jmd.pdf Restricted Access | Peer-reviewed author version | 191.81 kB | Adobe PDF | View/Open Request a copy |
| nejmsr1203730.pdf | Published version | 409.11 kB | Adobe PDF | View/Open |
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