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Title: Recommendations for the Management of Hepatitis C Virus Infection Among People Who Inject Drugs
Authors: ROBAEYS, Geert 
Grebely, Jason
Mauss, Stefan
Bruggmann, Philip
Moussalli, Joseph
De Gottardi, Andrea
Swan, Tracy
ARAIN, Amber 
Kautz, Achim
Stoever, Heino
Wedemeyer, Heiner
Schaefer, Martin
Taylor, Lynn
Backmund, Markus
Dalgard, Olav
Prins, Maria
Dore, Gregory J.
Issue Date: 2013
Abstract: In the developed world, the majority of new and existing hepatitis C virus (HCV) infections occur among people who inject drugs (PWID). The burden of HCV-related liver disease in this group is increasing, but treatment uptake among PWID remains low. Among PWID, there are a number of barriers to care that should be considered and systematically addressed, but these barriers should not exclude PWID from HCV treatment. Furthermore, it has been clearly demonstrated that HCV treatment is safe and effective across a broad range of multidisciplinary healthcare settings. Given the burden of HCV-related disease among PWID, strategies to enhance HCV assessment and treatment in this group are urgently needed. These recommendations demonstrate that treatment among PWID is feasible and provides a framework for HCV assessment, management, and treatment. Further research is needed to evaluate strategies to enhance assessment, adherence, and SVR among PWID, particularly as new treatments for HCV infection become available.
Notes: [Robaeys, Geert; Arain, Amber] Ziekenhuis Oost Limburg, Dept Gastroenterol & Hepatol, B-3600 Genk, Belgium. [Robaeys, Geert] Hasselt Univ, UZ Leuven, Dept Hepatol, Louvain, Belgium. [Robaeys, Geert; Arain, Amber] Hasselt Univ, Limburg Clin Res Program, Fac Med & Life Sci, Louvain, Belgium. [Grebely, Jason; Dore, Gregory J.] Univ New S Wales, Kirby Inst, Sydney, NSW, Australia. [Mauss, Stefan] Ctr HIV & Hepatogastroenterol, Dusseldorf, Germany. [Bruggmann, Philip] Arud Ctr Addict Med, Zurich, Switzerland. [Moussalli, Joseph] Hop La Pitie Salpetriere, Paris, France. [Moussalli, Joseph] Univ Paris 06, Paris, France. [De Gottardi, Andrea] Univ Bern, Inselspital, Clin Visceral Surg & Med, CH-3010 Bern, Switzerland. [Swan, Tracy] Treatment Act Grp, New York, NY USA. [Kautz, Achim] European Liver Patients Assoc, Cologne, Germany. [Stoever, Heino] Univ Appl Sci, Inst Addict Res, Frankfurt, Germany. [Wedemeyer, Heiner] Leibniz Univ Hannover, Dept Gastroenterol Hepatol & Endocrinol, Hannover, Germany. [Schaefer, Martin] Kliniken Essen Mitte, Dept Psychiat Psychotherapy & Addict Med, Essen, Germany. [Schaefer, Martin] Charite Univ Med Berlin, Dept Psychiat & Psychotherapy CCM, Berlin, Germany. [Taylor, Lynn] Brown Univ, Dept Med, Providence, RI 02912 USA. [Backmund, Markus] Univ Munich, Munich, Germany. [Backmund, Markus] Praxiszentrum Tal Munich, Munich, Germany. [Dalgard, Olav] Akershus Univ Hosp, Dept Infect Dis, Lorenskog, Norway. [Prins, Maria] Univ Amsterdam, Acad Med Ctr, Dept Res, Cluster Infect Dis,Publ Hlth Serv Amsterdam, NL-1105 AZ Amsterdam, Netherlands. [Prins, Maria] Univ Amsterdam, Acad Med Ctr, Dept Internal Med, Ctr Infect & Immun Amsterdam, NL-1105 AZ Amsterdam, Netherlands. [Dore, Gregory J.] St Vincents Hosp, HIV Immunol Infect Dis Clin Serv Unit, Sydney, NSW 2010, Australia.
Keywords: drug users; injecting; injection; guidelines; HCV; HIV;Immunology; Infectious Diseases; Microbiology
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ISSN: 1058-4838
e-ISSN: 1537-6591
DOI: 10.1093/cid/cit302
ISI #: 000322378900017
Category: A1
Type: Journal Contribution
Validations: ecoom 2014
Appears in Collections:Research publications

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