Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/15512
Title: Is Motor Learning Mediated by tDCS Intensity?
Authors: CUYPERS, Koen 
LEENUS, Daphnie 
van den Berg, Femke E.
Nitsche, Michael A.
THIJS, Herbert 
Wenderoth, Nicole
MEESEN, Raf 
Issue Date: 2013
Publisher: PUBLIC LIBRARY SCIENCE
Source: PLOS ONE, 8 (6)
Abstract: Although tDCS has been shown to improve motor learning, previous studies reported rather small effects. Since physiological effects of tDCS depend on intensity, the present study evaluated this parameter in order to enhance the effect of tDCS on skill acquisition. The effect of different stimulation intensities of anodal tDCS (atDCS) was investigated in a double blind, sham controlled crossover design. In each condition, thirteen healthy subjects were instructed to perform a unimanual motor (sequence) learning task. Our results showed (1) a significant increase in the slope of the learning curve and (2) a significant improvement in motor performance at retention for 1.5 mA atDCS as compared to sham tDCS. No significant differences were reported between 1 mA atDCS and sham tDCS; and between 1.5 mA atDCS and 1 mA atDCS.
Notes: [Cuypers, Koen; Leenus, Daphnie J. F.; Meesen, Raf L. J.] Hasselt Univ, BIOMED Biomed Res Inst, Diepenbeek, Belgium. [Cuypers, Koen; Leenus, Daphnie J. F.; Thijs, Herbert; Meesen, Raf L. J.] PHL Univ Coll, REVAL Res Inst, Diepenbeek, Belgium. [Cuypers, Koen; van den Berg, Femke E.; Wenderoth, Nicole; Meesen, Raf L. J.] Katholieke Univ Leuven, Dept Biomed Kinesiol, Motor Control Lab, B-3001 Heverlee, Belgium. [Nitsche, Michael A.] Univ Gottingen, Dept Clin Neurophysiol, D-37073 Gottingen, Germany. [Thijs, Herbert] Hasselt Univ, I BioStat Interuniv Inst Biostat & Stat Bioinfir, Diepenbeek, Belgium. [Thijs, Herbert] Katholieke Univ Leuven, Louvain, Belgium. [Wenderoth, Nicole; Meesen, Raf L. J.] ETH, Neural Control Movement Lab, Dept Hlth Sci & Technol, Zurich, Switzerland.
Keywords: Multidisciplinary Sciences
Document URI: http://hdl.handle.net/1942/15512
ISSN: 1932-6203
e-ISSN: 1932-6203
DOI: 10.1371/journal.pone.0067344
ISI #: 000321738400136
Category: A1
Type: Journal Contribution
Validations: ecoom 2014
Appears in Collections:Research publications

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