Please use this identifier to cite or link to this item:
|Title:||Changes in Corticomotor Excitability and Intracortical Inhibition of the Primary Motor Cortex Forearm Area Induced by Anodal tDCS||Authors:||Zhang, Xue
Woolley, Daniel G.
Swinnen, Stephan P.
|Issue Date:||2014||Source:||PLOS ONE, 9 (7)||Abstract:||Objective: Previous studies have investigated how tDCS over the primary motor cortex modulates excitability in the intrinsic hand muscles. Here, we tested if tDCS changes corticomotor excitability and/or cortical inhibition when measured in the extensor carpi radialis (ECR) and if these aftereffects can be successfully assessed during controlled muscle contraction. Methods: We implemented a double blind cross-over design in which participants (n = 16) completed two sessions where the aftereffects of 20 min of 1 mA (0.04 mA/cm(2)) anodal vs sham tDCS were tested in a resting muscle, and two more sessions where the aftereffects of anodal vs sham tDCS were tested in an active muscle. Results: Anodal tDCS increased corticomotor excitability in ECR when aftereffects were measured with a low-level controlled muscle contraction. Furthermore, anodal tDCS decreased short interval intracortical inhibition but only when measured at rest and after non-responders (n = 2) were removed. We found no changes in the cortical silent period. Conclusion: These findings suggest that targeting more proximal muscles in the upper limb with anodal tDCS is achievable and corticomotor excitability can be assessed in the presence of a low-level controlled contraction of the target muscle.||Notes:||Wenderoth, N (reprint author), Katholieke Univ Leuven, Dept Kinesiol, Motor Control Lab, Movement Control & Neuroplast Res Grp, Leuven, Belgium.firstname.lastname@example.org||Document URI:||http://hdl.handle.net/1942/17126||ISSN:||1932-6203||e-ISSN:||1932-6203||DOI:||10.1371/journal.pone.0101496||ISI #:||000338637300050||Rights:||© 2014 Zhang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.||Category:||A1||Type:||Journal Contribution||Validations:||ecoom 2015|
|Appears in Collections:||Research publications|
Show full item record
checked on Sep 5, 2020
WEB OF SCIENCETM
checked on May 13, 2022
checked on May 15, 2022
checked on May 15, 2022
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.