Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/17126
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dc.contributor.authorZhang, Xue-
dc.contributor.authorWoolley, Daniel G.-
dc.contributor.authorSwinnen, Stephan P.-
dc.contributor.authorFeys, Hilde-
dc.contributor.authorMEESEN, Raf-
dc.contributor.authorWenderoth, Nicole-
dc.date.accessioned2014-09-04T09:51:57Z-
dc.date.available2014-09-04T09:51:57Z-
dc.date.issued2014-
dc.identifier.citationPLOS ONE, 9 (7)-
dc.identifier.issn1932-6203-
dc.identifier.urihttp://hdl.handle.net/1942/17126-
dc.description.abstractObjective: Previous studies have investigated how tDCS over the primary motor cortex modulates excitability in the intrinsic hand muscles. Here, we tested if tDCS changes corticomotor excitability and/or cortical inhibition when measured in the extensor carpi radialis (ECR) and if these aftereffects can be successfully assessed during controlled muscle contraction. Methods: We implemented a double blind cross-over design in which participants (n = 16) completed two sessions where the aftereffects of 20 min of 1 mA (0.04 mA/cm(2)) anodal vs sham tDCS were tested in a resting muscle, and two more sessions where the aftereffects of anodal vs sham tDCS were tested in an active muscle. Results: Anodal tDCS increased corticomotor excitability in ECR when aftereffects were measured with a low-level controlled muscle contraction. Furthermore, anodal tDCS decreased short interval intracortical inhibition but only when measured at rest and after non-responders (n = 2) were removed. We found no changes in the cortical silent period. Conclusion: These findings suggest that targeting more proximal muscles in the upper limb with anodal tDCS is achievable and corticomotor excitability can be assessed in the presence of a low-level controlled contraction of the target muscle.-
dc.description.sponsorshipThis work was funded by the Flanders Fund for Scientific Research (Project G. 0758.10). Xue Zhang is a pre-doctoral fellow of the Flanders Fund for Scientific Research. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.-
dc.language.isoen-
dc.rights© 2014 Zhang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.-
dc.titleChanges in Corticomotor Excitability and Intracortical Inhibition of the Primary Motor Cortex Forearm Area Induced by Anodal tDCS-
dc.typeJournal Contribution-
dc.identifier.issue7-
dc.identifier.volume9-
local.format.pages10-
local.bibliographicCitation.jcatA1-
dc.description.notesWenderoth, N (reprint author), Katholieke Univ Leuven, Dept Kinesiol, Motor Control Lab, Movement Control & Neuroplast Res Grp, Leuven, Belgium.nicole.wenderoth@hest.ethz.ch-
local.type.refereedRefereed-
local.type.specifiedArticle-
dc.identifier.doi10.1371/journal.pone.0101496-
dc.identifier.isi000338637300050-
item.contributorMEESEN, Raf-
item.contributorWenderoth, Nicole-
item.contributorWoolley, Daniel G.-
item.contributorSwinnen, Stephan P.-
item.contributorFeys, Hilde-
item.contributorZhang, Xue-
item.validationecoom 2015-
item.fulltextWith Fulltext-
item.fullcitationZhang, Xue; Woolley, Daniel G.; Swinnen, Stephan P.; Feys, Hilde; MEESEN, Raf & Wenderoth, Nicole (2014) Changes in Corticomotor Excitability and Intracortical Inhibition of the Primary Motor Cortex Forearm Area Induced by Anodal tDCS. In: PLOS ONE, 9 (7).-
item.accessRightsOpen Access-
crisitem.journal.issn1932-6203-
crisitem.journal.eissn1932-6203-
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