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http://hdl.handle.net/1942/19159
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DC Field | Value | Language |
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dc.contributor.author | SAENEN, Eline | - |
dc.contributor.author | HOREMANS, Nele | - |
dc.contributor.author | VANHOUDT, Nathalie | - |
dc.contributor.author | VANDENHOVE, Hildegarde | - |
dc.contributor.author | BIERMANS, Geert | - |
dc.contributor.author | Van Hees, May | - |
dc.contributor.author | Wannijn, Jean | - |
dc.contributor.author | VANGRONSVELD, Jaco | - |
dc.contributor.author | CUYPERS, Ann | - |
dc.date.accessioned | 2015-09-15T11:42:06Z | - |
dc.date.available | 2015-09-15T11:42:06Z | - |
dc.date.issued | 2015 | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 16 (6), p. 12405-12423 | - |
dc.identifier.issn | 1422-0067 | - |
dc.identifier.uri | http://hdl.handle.net/1942/19159 | - |
dc.description.abstract | To evaluate the environmental impact of uranium (U) contamination, it is important to investigate the effects of U at ecologically relevant conditions. Since U speciation, and hence its toxicity, strongly depends on environmental pH, the present study aimed to investigate dose-dependent effects of U at pH 7.5. Arabidopsis thaliana plants (Mouse-ear Cress) were exposed for three days to different U concentrations at pH 7.5. In the roots, the increased capacities of ascorbate peroxidase and glutathione reductase indicate an important role for the ascorbate-glutathione cycle during U-induced stress. However, a significant decrease in the ascorbate redox state was observed after exposure to 75 and 100 mu M U, indicating that those roots are severely stressed. In accordance with the roots, the ascorbate-glutathione cycle plays an important role in the antioxidative defence systems in A. thaliana leaves exposed to U at pH 7.5 as the ascorbate and glutathione biosynthesis were upregulated. In addition, small inductions of enzymes of the antioxidative defence system were observed at lower U concentrations to counteract the U-induced stress. However, at higher U concentrations it seems that the antioxidative defence system of the leaves collapses as reductions in enzyme activities and gene expression levels were observed. | - |
dc.description.sponsorship | This work was supported by a grant for Eline Saenen from the Belgian Nuclear Research Centre (SCK center dot CEN). | - |
dc.language.iso | en | - |
dc.publisher | MDPI AG | - |
dc.rights | © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/). | - |
dc.subject.other | uranium toxicity; Arabidopsis thaliana; oxidative stress; gene expression; ascorbate-glutathione cycle | - |
dc.title | Induction of Oxidative Stress and Antioxidative Mechanisms in Arabidopsis thaliana after Uranium Exposure at pH 7.5 | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 12423 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 12405 | - |
dc.identifier.volume | 16 | - |
local.format.pages | 19 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Saenen, Eline; Horemans, Nele; Vanhoudt, Nathalie; Vandenhove, Hildegarde; Biermans, Geert; Van Hees, May; Wannijn, Jean] Belgian Nucl Res Ctr SCK CEN, Biosphere Impact Studies, B-2400 Mol, Belgium. [Saenen, Eline; Biermans, Geert; Vangronsveld, Jaco; Cuypers, Ann] Hasselt Univ, Ctr Environm Sci, B-3590 Diepenbeek, Belgium. | - |
local.publisher.place | BASEL | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.3390/ijms160612405 | - |
dc.identifier.isi | 000357492800035 | - |
item.fulltext | With Fulltext | - |
item.accessRights | Open Access | - |
item.contributor | SAENEN, Eline | - |
item.contributor | HOREMANS, Nele | - |
item.contributor | VANHOUDT, Nathalie | - |
item.contributor | VANDENHOVE, Hildegarde | - |
item.contributor | BIERMANS, Geert | - |
item.contributor | Van Hees, May | - |
item.contributor | Wannijn, Jean | - |
item.contributor | VANGRONSVELD, Jaco | - |
item.contributor | CUYPERS, Ann | - |
item.fullcitation | SAENEN, Eline; HOREMANS, Nele; VANHOUDT, Nathalie; VANDENHOVE, Hildegarde; BIERMANS, Geert; Van Hees, May; Wannijn, Jean; VANGRONSVELD, Jaco & CUYPERS, Ann (2015) Induction of Oxidative Stress and Antioxidative Mechanisms in Arabidopsis thaliana after Uranium Exposure at pH 7.5. In: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 16 (6), p. 12405-12423. | - |
item.validation | ecoom 2016 | - |
crisitem.journal.issn | 1661-6596 | - |
crisitem.journal.eissn | 1422-0067 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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saenen 1.pdf | Published version | 924.8 kB | Adobe PDF | View/Open |
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