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http://hdl.handle.net/1942/1958
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DC Field | Value | Language |
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dc.contributor.author | Mossong, J | - |
dc.contributor.author | Putz, L | - |
dc.contributor.author | SHKEDY, Ziv | - |
dc.contributor.author | Schneider, F | - |
dc.date.accessioned | 2007-11-09T15:14:07Z | - |
dc.date.available | 2007-11-09T15:14:07Z | - |
dc.date.issued | 2006 | - |
dc.identifier.citation | EPIDEMIOLOGY AND INFECTION, 134(3). p. 573-578 | - |
dc.identifier.issn | 0950-2688 | - |
dc.identifier.uri | http://hdl.handle.net/1942/1958 | - |
dc.description.abstract | A large serosurvey was carried out in Luxembourg in 2000-2001, to determine the population immunity against a number of vaccine-preventable infections including diphtheria and pertussis. Immunity to diphtheria and pertussis was assessed using an in-house neutralization assay and a commercial ELISA test respectively. Mean pertussis antibody activity decreased from 4 to 8 years of age, reflecting the effects of waning of vaccine-induced immunity. Mean pertussis antibody activity increased during adolescence due to infection in previously vaccinated individuals and levelled out after approximately 20 years of age. For adults > 25 years age, a statistically significant 30% difference in mean antibody activity between men and women was observed. The proportion of seronegatives for diphtheria among children and adolescents aged < 20 years was 2(.)5% reflecting the high vaccination coverage. The proportion seronegative for diphtheria tended to increase with age such that 42% of individuals aged > 40 years were seronegative. Our study supports the recently introduced acellular pertussis vaccine booster at 6 years to reduce pertussis transmission in school-aged children and adolescents. | - |
dc.language | English | - |
dc.language.iso | en | - |
dc.publisher | CAMBRIDGE UNIV PRESS | - |
dc.title | Seroepidemiology of diphtheria and pertussis in Luxembourg in 2000 | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 578 | - |
dc.identifier.issue | 3 | - |
dc.identifier.spage | 573 | - |
dc.identifier.volume | 134 | - |
local.format.pages | 6 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Lab Natl Sante, L-1011 Luxembourg, Luxembourg. CRP Sante, Luxembourg, Luxembourg. Limburgs Univ Ctr, Ctr Stat, Diepenbeek, Belgium.Mossong, J, Lab Natl Sante, POB 1102, L-1011 Luxembourg, Luxembourg.joel.mossong@lns.etat.lu | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.bibliographicCitation.oldjcat | A1 | - |
dc.identifier.doi | 10.1017/S0950268805005662 | - |
dc.identifier.isi | 000237786200018 | - |
item.fullcitation | Mossong, J; Putz, L; SHKEDY, Ziv & Schneider, F (2006) Seroepidemiology of diphtheria and pertussis in Luxembourg in 2000. In: EPIDEMIOLOGY AND INFECTION, 134(3). p. 573-578. | - |
item.fulltext | With Fulltext | - |
item.validation | ecoom 2007 | - |
item.contributor | Mossong, J | - |
item.contributor | Putz, L | - |
item.contributor | SHKEDY, Ziv | - |
item.contributor | Schneider, F | - |
item.accessRights | Restricted Access | - |
crisitem.journal.issn | 0950-2688 | - |
crisitem.journal.eissn | 1469-4409 | - |
Appears in Collections: | Research publications |
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yy.pdf Restricted Access | Published version | 6.28 MB | Adobe PDF | View/Open Request a copy |
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