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http://hdl.handle.net/1942/24229
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DC Field | Value | Language |
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dc.contributor.author | THIJSSEN, Annelies | - |
dc.contributor.author | CREEMERS, An | - |
dc.contributor.author | VAN DER ELST, Wim | - |
dc.contributor.author | Creemers, Eva | - |
dc.contributor.author | Vandormael, Eva | - |
dc.contributor.author | Dhont, Nathalie | - |
dc.contributor.author | OMBELET, Willem | - |
dc.date.accessioned | 2017-08-16T13:56:56Z | - |
dc.date.available | 2017-08-16T13:56:56Z | - |
dc.date.issued | 2017 | - |
dc.identifier.citation | REPRODUCTIVE BIOMEDICINE ONLINE, 34(5), p. 463-472 | - |
dc.identifier.issn | 1472-6483 | - |
dc.identifier.uri | http://hdl.handle.net/1942/24229 | - |
dc.description.abstract | The aim was to examine the value of different covariates in the prediction of intrauterine insemination (IUI) success. Between July 2011 and September 2015, data from 1401 IUI cycles with homologous semen in 556 couples were collected prospectively, by questionnaire, in a tertiary referral infertility centre. Statistical analysis was performed using generalized estimating equations (GEEs). GEEs were used instead of an ordinary logistic regression model to take into account the correlation between observations from the same person. The primary outcome parameter was clinical pregnancy rate (CPR), confirmed with a gestational sac and fetal heartbeat on ultrasonography at 7-8 weeks. An overall CPR of 9.5% per cycle was observed. Uni-variate statistical analysis revealed female and male age, male smoking, female body mass index, ovarian stimulation and inseminating motile count (IMC) as covariates significantly influencing CPR per cycle. Multivariate GEE analysis revealed that the only valuable prognostic covariates included female age, male smoking and infertility status (i.e. primary/secondary infertility). IMC showed a significant curvilinear relationship, with first an increase and then a decrease in pregnancy rate. (C) 2017 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved. | - |
dc.description.sponsorship | This study is part of the 'Limburg Clinical Research Program (LCRP) UHasselt-ZOL-Jessa', supported by the foundation Limburg Sterk Merk, province of Limburg, Flemish government, Hasselt University, Ziekenhuis Oost-Limburg and Jessa Hospital. | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.rights | © 2017 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved. | - |
dc.subject.other | Homologous semen; Intrauterine insemination; Prognostic factor; Prospective cohort study; Success rate | - |
dc.subject.other | homologous semen; intrauterine insemination; prognostic factor; prospective cohort study; success rate | - |
dc.title | Predictive value of different covariates influencing pregnancy rate following intrauterine insemination with homologous semen: a prospective cohort study | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 472 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 463 | - |
dc.identifier.volume | 34 | - |
local.format.pages | 10 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Thijssen, Annelies; Creemers, Eva; Vandormael, Eva; Dhont, Nathalie; Ombelet, Willem] Genk Inst Fertil Technol, Ziekenhuis Oost Limburg, Dept Obstet & Gynecol, Schiepse Bos 6, B-3600 Genk, Belgium. [Thijssen, Annelies; Ombelet, Willem] Hasselt Univ, Dept Physiol, Martelarenlaan 42, B-3500 Hasselt, Belgium. [Creemers, An; Van der Elst, Wim] Hasselt Univ, Ctr Stat CENSTAT, Agoralaan Bldg D, B-3590 Diepenbeek, Belgium. | - |
local.publisher.place | OXFORD | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.rbmo.2017.01.016 | - |
dc.identifier.isi | 000401128200004 | - |
item.validation | ecoom 2018 | - |
item.accessRights | Restricted Access | - |
item.fullcitation | THIJSSEN, Annelies; CREEMERS, An; VAN DER ELST, Wim; Creemers, Eva; Vandormael, Eva; Dhont, Nathalie & OMBELET, Willem (2017) Predictive value of different covariates influencing pregnancy rate following intrauterine insemination with homologous semen: a prospective cohort study. In: REPRODUCTIVE BIOMEDICINE ONLINE, 34(5), p. 463-472. | - |
item.fulltext | With Fulltext | - |
item.contributor | THIJSSEN, Annelies | - |
item.contributor | CREEMERS, An | - |
item.contributor | VAN DER ELST, Wim | - |
item.contributor | Creemers, Eva | - |
item.contributor | Vandormael, Eva | - |
item.contributor | Dhont, Nathalie | - |
item.contributor | OMBELET, Willem | - |
crisitem.journal.issn | 1472-6483 | - |
crisitem.journal.eissn | 1472-6491 | - |
Appears in Collections: | Research publications |
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thijssen 1.pdf Restricted Access | Published version | 443.63 kB | Adobe PDF | View/Open Request a copy |
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