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http://hdl.handle.net/1942/27695
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DC Field | Value | Language |
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dc.contributor.author | PIETERS, Zoe | - |
dc.contributor.author | Saad, Neil J. | - |
dc.contributor.author | Antillon, Marina | - |
dc.contributor.author | Pitzer, Virginia E. | - |
dc.contributor.author | Bilcke, Joke | - |
dc.date.accessioned | 2019-02-11T11:02:10Z | - |
dc.date.available | 2019-02-11T11:02:10Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | CLINICAL INFECTIOUS DISEASES, 67(4), p. 628-638 | - |
dc.identifier.issn | 1058-4838 | - |
dc.identifier.uri | http://hdl.handle.net/1942/27695 | - |
dc.description.abstract | Enteric fever is a febrile illness, occurring mostly in Asia and Africa, which can present as a severe and possibly fatal disease. Currently, a case fatality rate (CFR) of 1% is assumed when evaluating the global burden of enteric fever. Until now, no meta-analysis has been conducted to summarize mortality from enteric fever. Therefore, we conducted a systematic review and meta-analysis to aggregate all available evidence. We estimated an overall CFR of 2.49% (95% confidence interval, 1.65%-3.75%; n = 44), and a CFR in hospitalized patients of 4.45% (2.85%-6.88%; n = 21 of 44). There was considerably heterogeneity in estimates of the CFR from individual studies. Neither age nor antimicrobial resistance were significant prognostic factors, but limited data were available for these analyses. The combined estimate of the CFR for enteric fever is higher than previously estimated, and the evaluation of prognostic factors, including antimicrobial resistance, urgently requires more data. | - |
dc.description.sponsorship | Bill & Melinda Gates Foundation [OPP1116967]; Research Foundation-Flanders (FWO); Belgian American Educational Foundation; Antwerp Study Centre for Infectious Diseases, University of Antwerp | - |
dc.language.iso | en | - |
dc.publisher | OXFORD UNIV PRESS INC | - |
dc.rights | © The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. | - |
dc.subject.other | typhoid fever; Salmonella enterica serovar Typhi; Salmonella enterica serovar Paratyphi; mortality; antimicrobial resistance | - |
dc.subject.other | typhoid fever; Salmonella enterica serovar Typhi; Salmonella enterica serovar Paratyphi; mortality; antimicrobial resistance | - |
dc.title | Case Fatality Rate of Enteric Fever in Endemic Countries: A Systematic Review and Meta-analysis | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 638 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 628 | - |
dc.identifier.volume | 67 | - |
local.format.pages | 11 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Pieters, Zoe; Bilcke, Joke] Univ Antwerp, Vaccine & Infect Dis Inst, Antwerp, Belgium. [Pieters, Zoe] Hasselt Univ, Dept Math & Stat, Diepenbeek, Belgium. [Saad, Neil J.; Antillon, Marina; Pitzer, Virginia E.] Yale Sch Publ Hlth, Dept Epidemiol Microbial Dis, New Haven, CT USA. | - |
local.publisher.place | CARY | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
dc.identifier.doi | 10.1093/cid/ciy190 | - |
dc.identifier.isi | 000441000000030 | - |
item.validation | ecoom 2019 | - |
item.fulltext | With Fulltext | - |
item.fullcitation | PIETERS, Zoe; Saad, Neil J.; Antillon, Marina; Pitzer, Virginia E. & Bilcke, Joke (2018) Case Fatality Rate of Enteric Fever in Endemic Countries: A Systematic Review and Meta-analysis. In: CLINICAL INFECTIOUS DISEASES, 67(4), p. 628-638. | - |
item.accessRights | Open Access | - |
item.contributor | PIETERS, Zoe | - |
item.contributor | Saad, Neil J. | - |
item.contributor | Antillon, Marina | - |
item.contributor | Pitzer, Virginia E. | - |
item.contributor | Bilcke, Joke | - |
crisitem.journal.issn | 1058-4838 | - |
crisitem.journal.eissn | 1537-6591 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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pieters 1.pdf | Published version | 1.28 MB | Adobe PDF | View/Open |
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