Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/28020
Title: Muscle wasting after coronary artery bypass graft surgery: impact on post-operative clinical status and effect of exercise-based rehabilitation
Authors: HANSEN, Dominique 
BOUJEMAA, Hajar 
VERBOVEN, Kenneth 
HENDRIKX, Marc 
RUMMENS, Jean-Luc 
FREDERIX, Ines 
OP 'T EIJNDE, Bert 
DENDALE, Paul 
Issue Date: 2020
Publisher: TAYLOR & FRANCIS LTD
Source: Acta cardiologica, 75 (5), p. 406-410
Abstract: Background: Coronary artery bypass graft (CABG) surgery is known to induce significant muscle wasting. It remains to be investigated whether muscle wasting after CABG surgery relates to a worse clinical status at entry of rehabilitation and exercise-based rehabilitation remediates such muscle wasting. Design: Prospective observational study. Methods: In 21 males, changes in lean tissue mass (LTM) after CABG surgery were assessed and during a 12-week endurance exercise-based rehabilitation intervention. Changes in blood parameters and cardiopulmonary exercise capcity were assessed, and relations with changes in LTM were analyzed. Results: LTM decreased by -1.9±2.5kg (p<0.05) within 3 weeks after CABG surgery: greater LTM loss related to a lower ventilatory threshold at entry of rehabilitation (r=0.58-0.61, p<0.05). LTM was fully restored (+2.1±2.4kg, p<0.05) during rehabilitation. Conclusion: In males, CABG-induced LTM reduction was associated with a worse aerobic exercise tolerance at entry of rehabilitation, but this LTM reduction was fully remediated by endurance exercise-based rehabilitation.
Keywords: Coronary bypass surgery;lean tissue mass;rehabilitation
Document URI: http://hdl.handle.net/1942/28020
ISSN: 0001-5385
e-ISSN: 1784-973X
DOI: 10.1080/00015385.2019.1598035
ISI #: WOS:000575195300004
Rights: 2019 Belgian Society of Cardiology
Category: A1
Type: Journal Contribution
Validations: ecoom 2021
Appears in Collections:Research publications

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