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Title: | Muscle wasting after coronary artery bypass graft surgery: impact on post-operative clinical status and effect of exercise-based rehabilitation | Authors: | HANSEN, Dominique BOUJEMAA, Hajar VERBOVEN, Kenneth HENDRIKX, Marc RUMMENS, Jean-Luc FREDERIX, Ines OP 'T EIJNDE, Bert DENDALE, Paul |
Issue Date: | 2020 | Publisher: | TAYLOR & FRANCIS LTD | Source: | Acta cardiologica, 75 (5), p. 406-410 | Abstract: | Background: Coronary artery bypass graft (CABG) surgery is known to induce significant muscle wasting. It remains to be investigated whether muscle wasting after CABG surgery relates to a worse clinical status at entry of rehabilitation and exercise-based rehabilitation remediates such muscle wasting. Design: Prospective observational study. Methods: In 21 males, changes in lean tissue mass (LTM) after CABG surgery were assessed and during a 12-week endurance exercise-based rehabilitation intervention. Changes in blood parameters and cardiopulmonary exercise capcity were assessed, and relations with changes in LTM were analyzed. Results: LTM decreased by -1.9±2.5kg (p<0.05) within 3 weeks after CABG surgery: greater LTM loss related to a lower ventilatory threshold at entry of rehabilitation (r=0.58-0.61, p<0.05). LTM was fully restored (+2.1±2.4kg, p<0.05) during rehabilitation. Conclusion: In males, CABG-induced LTM reduction was associated with a worse aerobic exercise tolerance at entry of rehabilitation, but this LTM reduction was fully remediated by endurance exercise-based rehabilitation. | Keywords: | Coronary bypass surgery;lean tissue mass;rehabilitation | Document URI: | http://hdl.handle.net/1942/28020 | ISSN: | 0001-5385 | e-ISSN: | 1784-973X | DOI: | 10.1080/00015385.2019.1598035 | ISI #: | WOS:000575195300004 | Rights: | 2019 Belgian Society of Cardiology | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2021 |
Appears in Collections: | Research publications |
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