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http://hdl.handle.net/1942/28742
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DC Field | Value | Language |
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dc.contributor.author | Coorevits, L. | - |
dc.contributor.author | Traen, A. | - |
dc.contributor.author | Binge, L. | - |
dc.contributor.author | Van Dorpe, J. | - |
dc.contributor.author | Praet, M. | - |
dc.contributor.author | Boelens, J. | - |
dc.contributor.author | PADALKO, Elizaveta | - |
dc.date.accessioned | 2019-07-16T14:41:31Z | - |
dc.date.available | 2019-07-16T14:41:31Z | - |
dc.date.issued | 2018 | - |
dc.identifier.citation | Clinical microbiology and infection (Print), 24(12), p. 1328-1332 | - |
dc.identifier.issn | 1198-743X | - |
dc.identifier.uri | http://hdl.handle.net/1942/28742 | - |
dc.description.abstract | Objectives: Sexually transmitted infections (STIs) are a global cause of acute illness. Early detection plays a crucial role in interrupting transmission and preventing complications. However, the accessibility of STI testing is curbed by the lack of an overall preferred sample type. By means of a prospective study in female sex workers (FSW), we compared the sensitivity of samples from different anatomical sites in detecting Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, Mycoplasma genitalium and human papillomavirus. Besides, we documented the prevalence of each STI in this high-risk population. Methods: We selected 303 FSW and tested them for each STI by nucleic acid amplification testing on two vaginal and cervical swabs from different manufacturers, cervical smear and first-void urine. The sensitivity of each sample type was compared for each infectious agent in order to identify a consensus sample type. Results: Vaginal swabs were superior to all other sample types, with an overall sensitivity of 86%. The sensitivity was the lowest for first-void urine, detecting only 63% of positive cases. The prevalence was 3.3% (10/299) for Neisseria gonorrhoeae; 9.0% (27/299) for Chlamydia trachomatis; 7.4% (22/298) for Trichomonas vaginalis; 10.8% (32/296) for Mycoplasma genitalium and 55.6% (158/284) for human papillomavirus. Conclusions: When testing for STIs, vaginal swabs are the sample of choice and first-void urine should be avoided. Designating (self-sampled) vaginal swabs as a consensus sample type enables harmonization of STI testing and extension of testing to large numbers of unscreened females. (C) 2018 European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. All rights reserved. | - |
dc.description.sponsorship | The FWO (Fonds Wetenschappelijk Onderzoek - Vlaanderen) has granted this study, embedded in a PhD Clinical Fellowship with application number 1700417N. | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.rights | ELSEVIER SCI LTD | - |
dc.subject.other | sexually transmitted infections; laboratory diagnosis; genital samples; chlamydia trachomatis; neisseria gonorrhoeae; human papillomavirus; mycoplasma genitalium; trichomonas vaginalis | - |
dc.subject.other | Chlamydia trachomatis; Genital samples; Human papillomavirus; Laboratory diagnosis; Mycoplasma genitalium; Neisseria gonorrhoeae; Sexually transmitted infections; Trichomonas vaginalis | - |
dc.title | Identifying a consensus sample type to test for Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Trichomonas vaginalis and human papillomavirus | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 1332 | - |
dc.identifier.issue | 12 | - |
dc.identifier.spage | 1328 | - |
dc.identifier.volume | 24 | - |
local.format.pages | 5 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Coorevits, L.; Boelens, J.; Padalko, E.] Ghent Univ Hosp, Dept Lab Med, Ghent, Belgium. [Coorevits, L.; Boelens, J.; Padalko, E.] Univ Ghent, Dept Clin Chem Microbiol & Immunol, Ghent, Belgium. [Traen, A.; Binge, L.] Pasop VZW, Ghent, Belgium. [Van Dorpe, J.; Praet, M.] Univ Ghent, Dept Pathol, Ghent, Belgium. [Praet, M.; Boelens, J.] Ghent Univ Hosp, Ghent, Belgium. [Padalko, E.] Hasselt Univ, Sch Life Sci, Diepenbeek, Belgium. | - |
local.publisher.place | OXFORD | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.cmi.2018.03.013 | - |
dc.identifier.isi | 000451052700019 | - |
local.uhasselt.international | no | - |
item.contributor | Coorevits, L. | - |
item.contributor | Traen, A. | - |
item.contributor | Binge, L. | - |
item.contributor | Van Dorpe, J. | - |
item.contributor | Praet, M. | - |
item.contributor | Boelens, J. | - |
item.contributor | PADALKO, Elizaveta | - |
item.fullcitation | Coorevits, L.; Traen, A.; Binge, L.; Van Dorpe, J.; Praet, M.; Boelens, J. & PADALKO, Elizaveta (2018) Identifying a consensus sample type to test for Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Trichomonas vaginalis and human papillomavirus. In: Clinical microbiology and infection (Print), 24(12), p. 1328-1332. | - |
item.accessRights | Open Access | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 1198-743X | - |
crisitem.journal.eissn | 1469-0691 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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coorevits2018.pdf | Peer-reviewed author version | 618.95 kB | Adobe PDF | View/Open |
PIIS1198743X18302234.pdf Restricted Access | Published version | 844.83 kB | Adobe PDF | View/Open Request a copy |
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