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http://hdl.handle.net/1942/28866
Title: | Chondroid metaplasia of paraspinal connective tissue in the degenerative spine | Authors: | STEVENS, Sjoerd AGTEN, Anouk Wisanto, Erika LO MONACO, Melissa VERBRUGGHE, Jonas TIMMERMANS, Annick LAMBRICHTS, Ivo VANDENABEELE, Frank |
Issue Date: | 2019 | Source: | Anatomy & Cell Biology, 52(2), p. 204-207 | Abstract: | A 51-year-old male was routinely biopsied during a paraspinal muscle study. The biopsy sample was taken from the right erector spinae muscle at the fourth lumbar vertebra. The patient had no history of (diagnosed) major back trauma. The obtained sample was histologically analyzed (hematoxylin and eosin, safranin O), and complementary magnetic resonance imaging was performed. The biopsied sample contained chondroid tissue. Based on its location, the biopsy sample was appointed as chondroid metaplasia. Although chondroid metaplasia is not uncommon in humans, this is the first report of chondroid metaplasia within the paraspinal connective tissue. We propose a novel mechanism to explain the paraspinal chrondrogenic changes, related to spinal degeneration. | Keywords: | Chondroid metaplasia; Paraspinal; Lumbar spine; Degeneration; Muscle biopsy | Document URI: | http://hdl.handle.net/1942/28866 | ISSN: | 2093-3665 | e-ISSN: | 2093-3673 | DOI: | 10.5115/acb.2019.52.2.204 | ISI #: | 000476464200014 | Rights: | This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. | Category: | A1 | Type: | Journal Contribution | Validations: | vabb 2022 |
Appears in Collections: | Research publications |
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Stevens et al. 2019.pdf | Published version | 611.21 kB | Adobe PDF | View/Open |
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