Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/29110
Title: | Microdosimetry at the CATANA 62 MeV proton beam with a sealed miniaturized TEPC | Authors: | Conte, Valeria BIANCHI, Anna Selva, Anna Petringa, Giada Cirrone, G. A. Pablo Parisi, Alessio Vanhavere, Filip Colautti, Paolo |
Issue Date: | 2019 | Publisher: | ELSEVIER SCI LTD | Source: | Physica Medica-European Journal of Medical Physics, 64(3), p. 114-122 | Abstract: | A new mini-TEPC with cylindrical sensitive volume of 0.9mm in diameter and height, and with external diameter of 2.7 mm, has been developed to work without gas flow. With such a mini counter we have measured the physical quality of the 62 MeV therapeutic proton beam of CATANA (Catania, Italy). Measurements were performed at six precise positions along the Spread-Out Bragg Peak (SOBP): 1.4, 19.4, 24.6, 29.0, 29.7 and 30.8 mm, corresponding to positions of clinical relevance (entrance, proximal, central, and distal-edge of the SOBP) or of high lineal energy transfer (LET) increment (distal-dose drop off). Without refilling the microdosimeter with new gas, the measurements were repeated at the same positions 4 months later, in order to study the stability of the response in sealed-mode operation. From the microdosimetric spectra the frequency-mean lineal energy yF and the dose-mean lineal energy yD were derived and compared with average LET values calculated by means of Geant4 simulations. The comparison points out, in particular, a good agreement between microdosimetric yD and the total dose-average LET_d, which is the average LET of the mixed radiation field, including the contribution by nuclear reactions. | Keywords: | TEPC; Microdosimetry; Proton therapy; Proton RBE | Document URI: | http://hdl.handle.net/1942/29110 | ISSN: | 1120-1797 | e-ISSN: | 1724-191X | DOI: | 10.1016/j.ejmp.2019.06.011 | ISI #: | WOS:000485006200016 | Rights: | 2019 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2020 |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
1-s2.0-S1120179719301474-main.pdf Restricted Access | Published version | 2.1 MB | Adobe PDF | View/Open Request a copy |
SCOPUSTM
Citations
3
checked on Sep 7, 2020
WEB OF SCIENCETM
Citations
38
checked on May 8, 2024
Page view(s)
128
checked on Sep 7, 2022
Download(s)
112
checked on Sep 7, 2022
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.