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Title: | Impact of the French Infectious Diseases Society's (SPILF) proposals for shorter antibiotic therapies | Authors: | Macheda, G. Luc, A. BERAUD, Guillaume Castan, B. Gauzit, R. Lesprit, P. Tattevin, P. Thilly, N. Pulcini, C. |
Issue Date: | 2019 | Publisher: | ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER | Source: | MEDECINE ET MALADIES INFECTIEUSES, 49(6), p. 456-462 | Abstract: | Objective. - To compare the practices of French infection specialists related to antibiotic therapy duration between 2016 and 2018. Methods. - We conducted two identical surveys (in 2016 and 2018) targeting hospital-based infection specialists (medical physicians, pharmacists) who gave at least weekly advice on antibiotic prescriptions. The questionnaire included 15 clinical vignettes. Part A asked about the durations of antibiotic therapies they would usually advise to prescribers, and part B asked about the shortest duration they would be willing to advise for the same clinical situations. Results. - We included 325 specialists (165 in 2016 and 160 in 2018), mostly infectious disease specialists (82.4%, 268/325), members of antibiotic stewardship teams in 72% (234/325) of cases. Shorter antibiotic treatments (as compared with the literature) were advised to prescribers in more than half of the vignettes by 71% (105/147) of respondents in 2018, versus 46% (69/150) in 2016 (P<0.001). Guidelines used by participants displayed fixed durations for 77% (123/160) of cases in 2018 versus 21% (35/165) in 2016. Almost all respondents (89%, 131/160) declared they were aware of the 2017 SPILF's proposal. Conclusion. - The release of guidelines promoting shorter durations of antibiotic therapy seems to have had a favourable impact on practices of specialists giving advice on antibiotic prescriptions. (C) 2019 Elsevier Masson SAS. All rights reserved. | Notes: | [Macheda, G.; Pulcini, C.] Univ Lorraine, CHRU Nancy, Infect Dis Dept, F-54000 Nancy, France. [Luc, A.; Thilly, N.] CHRU Nancy, Plateforme Aide Rech Clin, F-54000 Nancy, France. [Beraud, G.] CHU Poitiers, Med Interne & Malad Infect, F-86021 Poitiers, France. [Beraud, G.] Univ Laval, CHU Quebec, Hop St Sacrement, Ctr Rech, Chemin St Foy, PQ, Canada. [Beraud, G.] Hasselt Univ, Interuniv Inst Biostat & Stat Bioinformat, Hasselt, Belgium. [Castan, B.] Ctr Hosp Ajaccio, Unite Fonct Infectiol Reg, F-20303 Ajaccio, France. [Gauzit, R.] Univ Paris 05, Hop Univ Paris Ctr, AP HP, Equipe Mobile Infectiol, Site Cochin, F-75014 Paris, France. [Lesprit, P.] Hop Foch, F-92151 Suresnes, France. [Tattevin, P.] CHU Rennes, Hop Pontchaillou, Malad Infect & Reanimat Med, F-35033 Rennes, France. [Thilly, N.; Pulcini, C.] Univ Lorraine, APEMAC, F-54000 Nancy, France. [Gauzit, R.; Lesprit, P.; Tattevin, P.; Pulcini, C.] SPILF, Vandoeuvre Les Nancy, France. [Beraud, G.; Pulcini, C.] ESCMID Study Grp Antimicrobial Stewardship ESGAP, Basel, Switzerland. | Keywords: | Antibiotic stewardship; Antibiotic; Guidelines;Infectious Diseases | Document URI: | http://hdl.handle.net/1942/29870 | ISSN: | 0399-077X | DOI: | 10.1016/j.medmal.2019.07.005 | ISI #: | 000487349300006 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2020 |
Appears in Collections: | Research publications |
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