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http://hdl.handle.net/1942/29956
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DC Field | Value | Language |
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dc.contributor.author | CLAESEN, Jurgen | - |
dc.contributor.author | VALKENBORG, Dirk | - |
dc.contributor.author | BURZYKOWSKI, Tomasz | - |
dc.date.accessioned | 2019-11-13T11:02:19Z | - |
dc.date.available | 2019-11-13T11:02:19Z | - |
dc.date.issued | 2019 | - |
dc.identifier.citation | JOURNAL OF MASS SPECTROMETRY, | - |
dc.identifier.issn | 1076-5174 | - |
dc.identifier.uri | http://hdl.handle.net/1942/29956 | - |
dc.description.abstract | Identification of peptides and proteins is a common task in mass spectrometry-based proteomics but often fails to deliver a comprehensive list of identifications. Downstream analysis, quantitative or qualitative, depends on the outcome of this process. Despite continuous improvement of computational methods, a large fraction of the screened peptides and/or proteins remains unidentified. We introduce here pacMASS, a method that de novo predicts the elemental composition of peptides and small proteins based on a single accurate mass, ie, the observed monoisotopic or average mass. This novel approach returns in a fast and memory efficient manner a limited number of elemental compositions per queried peptide or protein. | - |
dc.description.sponsorship | The authors would like to thank Romano Hebeler and Frank Aerts from Bruker for providing us with the bovine serum album in A data | - |
dc.language.iso | en | - |
dc.publisher | WILEY | - |
dc.rights | 2019 John Wiley & Sons,Ltd. | - |
dc.subject.other | bioinformatics; identification; mass spectrometry; MS1; proteomics | - |
dc.subject.other | bioinformatics; identification; massspectrometry; MS1; proteomics | - |
dc.title | De novo prediction of the elemental composition of peptides and proteins based on a single mass | - |
dc.type | Journal Contribution | - |
local.format.pages | 10 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | [Claesen, Jurgen; Valkenborg, Dirk; Burzykowski, Tomasz] Hasselt Univ, I BioStat, Hasselt, Belgium. | - |
local.publisher.place | HOBOKEN | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1002/jms.4367 | - |
dc.identifier.isi | 000489216400001 | - |
item.validation | ecoom 2020 | - |
item.contributor | CLAESEN, Jurgen | - |
item.contributor | VALKENBORG, Dirk | - |
item.contributor | BURZYKOWSKI, Tomasz | - |
item.accessRights | Open Access | - |
item.fullcitation | CLAESEN, Jurgen; VALKENBORG, Dirk & BURZYKOWSKI, Tomasz (2019) De novo prediction of the elemental composition of peptides and proteins based on a single mass. In: JOURNAL OF MASS SPECTROMETRY,. | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 1076-5174 | - |
crisitem.journal.eissn | 1096-9888 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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claesen 1.pdf Restricted Access | Published version | 1.34 MB | Adobe PDF | View/Open Request a copy |
pacMASS_full_resubmitted_JMS_v2.pdf | Peer-reviewed author version | 430.25 kB | Adobe PDF | View/Open |
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