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http://hdl.handle.net/1942/31291
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DC Field | Value | Language |
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dc.contributor.author | Crutsen, Mieke R. C. | - |
dc.contributor.author | Keene, Spencer J. | - |
dc.contributor.author | Janssen, Daisy J. A. | - |
dc.contributor.author | Nakken, Nienke | - |
dc.contributor.author | Groenen, Miriam T. | - |
dc.contributor.author | van Kuijk, Sander M. J. | - |
dc.contributor.author | Franssen, Frits M. E. | - |
dc.contributor.author | Wouters, Emiel F. M. | - |
dc.contributor.author | SPRUIT, Martijn A. | - |
dc.date.accessioned | 2020-06-16T11:22:25Z | - |
dc.date.available | 2020-06-16T11:22:25Z | - |
dc.date.issued | 2020 | - |
dc.date.submitted | 2020-06-02T13:03:40Z | - |
dc.identifier.citation | JOURNAL OF CLINICAL MEDICINE, 9 (3) (Art° 636) | - |
dc.identifier.uri | http://hdl.handle.net/1942/31291 | - |
dc.description.abstract | Background and objective: Exacerbation(s) of chronic obstructive pulmonary disease (eCOPD) entail important events describing an acute deterioration of respiratory symptoms. Changes in medication and/or hospitalization are needed to gain control over the event. However, an exacerbation leading to hospitalization is associated with a worse prognosis for the patient. The objective of this study is to explore factors that could predict the probability of an eCOPD-related hospitalization. Methods: Data from 128 patients with COPD included in a prospective, longitudinal study were used. At baseline, physical, emotional, and social status of the patients were assessed. Moreover, hospital admission during a one year follow-up was captured. Different models were made based on univariate analysis, literature, and practice. These models were combined to come to one final overall prediction model. Results: During follow-up, 31 (24.2%) participants were admitted for eCOPD. The overall model contained six significant variables: currently smoking (OR = 3.93), forced vital capacity (FVC; OR = 0.97), timed-up-and-go time (TUG-time) (OR = 14.16), knowledge (COPD knowledge questionnaire, percentage correctly answered questions (CIROPD%correct)) (<60% (OR = 1.00); 60%-75%: (OR = 0.30); >75%: (OR = 1.94), eCOPD history (OR = 9.98), and care dependency scale (CDS) total score (OR = 1.12). This model was well calibrated (goodness-of-fit test: p = 0.91) and correctly classified 79.7% of the patients. Conclusion: A combination of TUG-time, eCOPD-related admission(s) prior to baseline, currently smoking, FVC, CDS total score, and CIROPD%correct allows clinicians to predict the probability of an eCOPD-related hospitalization. | - |
dc.language.iso | en | - |
dc.publisher | MDPI | - |
dc.rights | 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | - |
dc.subject.other | chronic obstructive pulmonary disease | - |
dc.subject.other | hospitalization | - |
dc.subject.other | disease progression | - |
dc.subject.other | prognosis | - |
dc.subject.other | predictors | - |
dc.title | Physical, Psychological, and Social Factors Associated with Exacerbation-Related Hospitalization in Patients with COPD | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 3 | - |
dc.identifier.volume | 9 | - |
local.format.pages | 13 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Crutsen, MRC (reprint author), MUMC, Dept Pulm Functioning, NL-6229 HX Maastricht, Netherlands.; Crutsen, MRC (reprint author), CIRO, Dept Res & Dev, NL-6058 NM Horn, Netherlands. | - |
dc.description.notes | mieke.crutsen@mumc.nl; spncrkn044@gmail.com; daisyjanssen@ciro-horn.nl; | - |
dc.description.notes | nienkenakken@ciro-horn.nl; miriamgroenen@ciro-horn.nl; | - |
dc.description.notes | sander.van.kuijk@mumc.nl; fritsfranssen@ciro-horn.nl; | - |
dc.description.notes | ewouters@ciro-horn.nl; martijnspruit@ciro-horn.nl | - |
dc.description.other | Crutsen, MRC (reprint author), MUMC, Dept Pulm Functioning, NL-6229 HX Maastricht, Netherlands; CIRO, Dept Res & Dev, NL-6058 NM Horn, Netherlands. mieke.crutsen@mumc.nl; spncrkn044@gmail.com; daisyjanssen@ciro-horn.nl; nienkenakken@ciro-horn.nl; miriamgroenen@ciro-horn.nl; sander.van.kuijk@mumc.nl; fritsfranssen@ciro-horn.nl; ewouters@ciro-horn.nl; martijnspruit@ciro-horn.nl | - |
local.publisher.place | ST ALBAN-ANLAGE 66, CH-4052 BASEL, SWITZERLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 636 | - |
dc.source.type | Article | - |
dc.identifier.doi | 10.3390/jcm9030636 | - |
dc.identifier.pmid | 32120911 | - |
dc.identifier.isi | WOS:000527278800025 | - |
dc.contributor.orcid | Janssen, Daisy/0000-0002-1827-9869 | - |
dc.identifier.eissn | 2077-0383 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.uhasselt.international | yes | - |
item.fullcitation | Crutsen, Mieke R. C.; Keene, Spencer J.; Janssen, Daisy J. A.; Nakken, Nienke; Groenen, Miriam T.; van Kuijk, Sander M. J.; Franssen, Frits M. E.; Wouters, Emiel F. M. & SPRUIT, Martijn A. (2020) Physical, Psychological, and Social Factors Associated with Exacerbation-Related Hospitalization in Patients with COPD. In: JOURNAL OF CLINICAL MEDICINE, 9 (3) (Art° 636). | - |
item.fulltext | With Fulltext | - |
item.validation | ecoom 2021 | - |
item.contributor | Crutsen, Mieke R. C. | - |
item.contributor | Keene, Spencer J. | - |
item.contributor | Janssen, Daisy J. A. | - |
item.contributor | Nakken, Nienke | - |
item.contributor | Groenen, Miriam T. | - |
item.contributor | van Kuijk, Sander M. J. | - |
item.contributor | Franssen, Frits M. E. | - |
item.contributor | Wouters, Emiel F. M. | - |
item.contributor | SPRUIT, Martijn A. | - |
item.accessRights | Open Access | - |
crisitem.journal.eissn | 2077-0383 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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jcm-09-00636-v2.pdf | Published version | 286.12 kB | Adobe PDF | View/Open |
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