Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS

Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/32447

Title:	Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS
Authors:	Perna, Eluisa Aguilera-Lizarraga, Javier Florens, Morgane V Jain, Piyush Theofanous, Stavroula A Hanning, Nikita De Man, Joris G Berg, Maya De Winter, Benedicte AGUIAR ALPIZAR, Yeranddy Talavera, Karel Vanden Berghe, Pieter Wouters, Mira Boeckxstaens, Guy
Issue Date:	2021
Publisher:	BMJ PUBLISHING GROUP
Source:	Gut, 70 (7), p. 1275 - 1286
Abstract:	Resolvins (RvD1, RvD2 and RvE1) are endogenous anti-inflammatory lipid mediators that display potent analgesic properties in somatic pain by modulating transient receptor potential vanilloid 1 (TRPV1) activation. To what extent these molecules could also have a beneficial effect on TRPV1 sensitisation and visceral hypersensitivity (VHS), mechanisms involved in IBS, remains unknown.
Keywords:	ION channels;abdominal pain;irritable bowel syndrome;neurogastroenterology;visceral hypersensitivity
Document URI:	http://hdl.handle.net/1942/32447
ISSN:	0017-5749
e-ISSN:	1468-3288
DOI:	10.1136/gutjnl-2020-321530
ISI #:	000667248900010
Rights:	Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ.
Category:	A1
Type:	Journal Contribution
Validations:	ecoom 2022
Appears in Collections:	Research publications

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