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http://hdl.handle.net/1942/32447| Title: | Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS | Authors: | Perna, Eluisa Aguilera-Lizarraga, Javier Florens, Morgane V Jain, Piyush Theofanous, Stavroula A Hanning, Nikita De Man, Joris G Berg, Maya De Winter, Benedicte AGUIAR ALPIZAR, Yeranddy Talavera, Karel Vanden Berghe, Pieter Wouters, Mira Boeckxstaens, Guy |
Issue Date: | 2021 | Publisher: | BMJ PUBLISHING GROUP | Source: | Gut, 70 (7), p. 1275 - 1286 | Abstract: | Resolvins (RvD1, RvD2 and RvE1) are endogenous anti-inflammatory lipid mediators that display potent analgesic properties in somatic pain by modulating transient receptor potential vanilloid 1 (TRPV1) activation. To what extent these molecules could also have a beneficial effect on TRPV1 sensitisation and visceral hypersensitivity (VHS), mechanisms involved in IBS, remains unknown. | Keywords: | ION channels;abdominal pain;irritable bowel syndrome;neurogastroenterology;visceral hypersensitivity | Document URI: | http://hdl.handle.net/1942/32447 | ISSN: | 0017-5749 | e-ISSN: | 1468-3288 | DOI: | 10.1136/gutjnl-2020-321530 | ISI #: | 000667248900010 | Rights: | Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ. | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2022 |
| Appears in Collections: | Research publications |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS.pdf | Peer-reviewed author version | 1.17 MB | Adobe PDF | View/Open |
| Effect of resolvins on sensitisation of TRPV1 and visceral hypersensitivity in IBS.pdf Restricted Access | Published version | 3.61 MB | Adobe PDF | View/Open Request a copy |
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