Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/32831
Title: | Stable HEV IgG seroprevalence in Belgium between 2006 and 2014 | Authors: | Ho, Erwin SCHENK, Julie Hutse, Veronik Suin, Vanessa Litzroth, Amber Blaizot, Stephanie HERZOG, Sereina Verburgh, Vera Jacques, Marjorie Rahman, Abbas Michielsen, Peter Van Damme, Pierre Van Gucht, Steven Theeten, Heidi HENS, Niel Vanwolleghem, Thomas |
Issue Date: | 2020 | Publisher: | WILEY | Source: | Journal of viral hepatitis (Print), 27 (11) , p. 1253 -1260 | Abstract: | Recent European studies suggest an emergence of hepatitis E virus (HEV) infection. We evaluated trends in birth cohort-specific HEV seroprevalence and regional differences in Belgium. HEV IgG seroprevalence was analysed on national serum banks (1579 and 2087 samples for 2006 and 2014, respectively. Hepatitis E virus antigen was tested on positive samples. Observed data were modelled using a generalized additive model with a complementary log-log link. No significant differences between birth cohorts or sexes were found. Modelling identified the individual's age and province as relevant factors. The probability of HEV seropositivity increases significantly with age. An estimated total of 434 819 (yearly rate of 54,352) (sero-)infections were found between 2006 and 2014. Overall, HEV IgG seroprevalences were 4.1% (64/1579, 95% CI 3.1-5.1) and 5.8% (121/2087, CI 4.8-6.9) in 2006 and 2014, respectively. Observed HEV antigen seroprevalence was 0.027% (1/3666) for the entire cohort. These results show stable HEV IgG seroprevalence in Belgium. | Notes: | Vanwolleghem, T (corresponding author), Antwerp Univ Hosp, Dept Gastroenterol & Hepatol, Edegem, Belgium. thomas.vanwolleghem@uza.be |
Other: | Vanwolleghem, T (corresponding author), Antwerp Univ Hosp, Dept Gastroenterol & Hepatol, Edegem, Belgium. thomas.vanwolleghem@uza.be | Keywords: | Belgium;epidemiology;Europe;hepatitis E | Document URI: | http://hdl.handle.net/1942/32831 | ISSN: | 1352-0504 | e-ISSN: | 1365-2893 | DOI: | 10.1111/jvh.13347 | ISI #: | WOS:000575345200016 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2021 |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
jvh.13347.pdf Restricted Access | Published version | 908.05 kB | Adobe PDF | View/Open Request a copy |
a169866.pdf | Peer-reviewed author version | 3.46 MB | Adobe PDF | View/Open |
WEB OF SCIENCETM
Citations
4
checked on Apr 15, 2024
Page view(s)
38
checked on Aug 9, 2022
Download(s)
6
checked on Aug 9, 2022
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.