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http://hdl.handle.net/1942/34599
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DC Field | Value | Language |
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dc.contributor.author | de Faria, Ana Paula | - |
dc.contributor.author | Modolo, Rodrigo | - |
dc.contributor.author | Chichareon, Ply | - |
dc.contributor.author | Chang, Chun-Chin | - |
dc.contributor.author | Kogame, Norihiro | - |
dc.contributor.author | Tomaniak, Mariusz | - |
dc.contributor.author | Takahashi, Kuniaki | - |
dc.contributor.author | Rademaker-Havinga, Tessa | - |
dc.contributor.author | Wykrzykowska, Joanna | - |
dc.contributor.author | de Winter, Rob J. | - |
dc.contributor.author | Ferreira, Rui C. | - |
dc.contributor.author | Sousa, Amanda | - |
dc.contributor.author | Lemos, Pedro A. | - |
dc.contributor.author | Garg, Scot | - |
dc.contributor.author | Hamm, Christian | - |
dc.contributor.author | Juni, Peter | - |
dc.contributor.author | VRANCKX, Pascal | - |
dc.contributor.author | Valgimigli, Marco | - |
dc.contributor.author | Windecker, Stephan | - |
dc.contributor.author | Onuma, Yoshinobu | - |
dc.contributor.author | Steg, Philippe Gabriel | - |
dc.contributor.author | Serruys, Patrick W. | - |
dc.date.accessioned | 2021-07-30T13:49:00Z | - |
dc.date.available | 2021-07-30T13:49:00Z | - |
dc.date.issued | 2020 | - |
dc.date.submitted | 2021-07-08T13:39:52Z | - |
dc.identifier.citation | Canadian journal of cardiology (Print) = Journal canadienne de cardiologie, 36 (5) , p. 747 -755 | - |
dc.identifier.uri | http://hdl.handle.net/1942/34599 | - |
dc.description.abstract | Background: We evaluated the association of pulse pressure (PP) and different antiplatelet regimes with clinical and safety outcomes in an all-comers percutaneous coronary intervention (PCI) population. Methods: In this analysis of GLOBAL LEADERS (n = 15,936) we compared the experimental therapy of 23 months of ticagrelor after 1 month of dual-antiplatelet therapy (DAPT) vs standard DAPT for 12 months followed by aspirin monotherapy in subjects who underwent PCI and were divided into 2 groups according to the median PP (60 mm Hg). The primary end point (all-cause death or new Q-wave myocardial infarction) and the composite end points: patient-oriented composite end points (POCE), Bleeding Academic Research Consortium (BARC) 3 or 5, and net adverse clinical events (NACE) were evaluated. Results: At 2 years, subjects in the high-PP group (n = 7971) had similar rates of the primary end point (4.3% vs 3.9%; P = 0.058), POCE (14.9% vs 12.7%; P = 0.051), and BARC 3 or 5 (2.5% vs 1.7%; P = 0.355) and higher rates of NACE (16.4% vs 13.7%; P = 0.037) compared with the low-PP group (n = 7965). Among patients with PP < 60 mm Hg, the primary end point (3.4% vs 4.4%, adjusted hazard ratio [aHR] 0.77, 95% confidence interval [CI] 0.61-0.96), POCE (11.8% vs 13.5%, aHR 0.86, 95% | - |
dc.language.iso | en | - |
dc.title | Association of Pulse Pressure With Clinical Outcomes in Patients Under Different Antiplatelet Strategies After Percutaneous Coronary Intervention: Analysis of GLOBAL LEADERS | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 755 | - |
dc.identifier.issue | 5 | - |
dc.identifier.spage | 747 | - |
dc.identifier.volume | 36 | - |
local.bibliographicCitation.jcat | A1 | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.cjca.2019.10.015 | - |
dc.identifier.isi | WOS:000532690200016 | - |
dc.contributor.orcid | Wykrzykowska, Joanna/0000-0001-7577-4084 | - |
local.provider.type | wosris | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.accessRights | Restricted Access | - |
item.fullcitation | de Faria, Ana Paula; Modolo, Rodrigo; Chichareon, Ply; Chang, Chun-Chin; Kogame, Norihiro; Tomaniak, Mariusz; Takahashi, Kuniaki; Rademaker-Havinga, Tessa; Wykrzykowska, Joanna; de Winter, Rob J.; Ferreira, Rui C.; Sousa, Amanda; Lemos, Pedro A.; Garg, Scot; Hamm, Christian; Juni, Peter; VRANCKX, Pascal; Valgimigli, Marco; Windecker, Stephan; Onuma, Yoshinobu; Steg, Philippe Gabriel & Serruys, Patrick W. (2020) Association of Pulse Pressure With Clinical Outcomes in Patients Under Different Antiplatelet Strategies After Percutaneous Coronary Intervention: Analysis of GLOBAL LEADERS. In: Canadian journal of cardiology (Print) = Journal canadienne de cardiologie, 36 (5) , p. 747 -755. | - |
item.contributor | de Faria, Ana Paula | - |
item.contributor | Modolo, Rodrigo | - |
item.contributor | Chichareon, Ply | - |
item.contributor | Chang, Chun-Chin | - |
item.contributor | Kogame, Norihiro | - |
item.contributor | Tomaniak, Mariusz | - |
item.contributor | Takahashi, Kuniaki | - |
item.contributor | Rademaker-Havinga, Tessa | - |
item.contributor | Wykrzykowska, Joanna | - |
item.contributor | de Winter, Rob J. | - |
item.contributor | Ferreira, Rui C. | - |
item.contributor | Sousa, Amanda | - |
item.contributor | Lemos, Pedro A. | - |
item.contributor | Garg, Scot | - |
item.contributor | Hamm, Christian | - |
item.contributor | Juni, Peter | - |
item.contributor | VRANCKX, Pascal | - |
item.contributor | Valgimigli, Marco | - |
item.contributor | Windecker, Stephan | - |
item.contributor | Onuma, Yoshinobu | - |
item.contributor | Steg, Philippe Gabriel | - |
item.contributor | Serruys, Patrick W. | - |
crisitem.journal.issn | 0828-282X | - |
crisitem.journal.eissn | 1916-7075 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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1-s2.0-S0828282X19313509-main.pdf Restricted Access | Published version | 1.14 MB | Adobe PDF | View/Open Request a copy |
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