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http://hdl.handle.net/1942/35376
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DC Field | Value | Language |
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dc.contributor.author | Alonso, Ricardo | - |
dc.contributor.author | Silva, Berenice | - |
dc.contributor.author | Garcea, Orlando | - |
dc.contributor.author | Correa Diaz, Patricio E. | - |
dc.contributor.author | dos Passos, Giordani Rodrigues | - |
dc.contributor.author | Ramirez Navarro, Deyanira A. | - |
dc.contributor.author | Garcia Valle, Luis A. | - |
dc.contributor.author | Rodriguez Salinas, Luis C. | - |
dc.contributor.author | Negrotto, Laura | - |
dc.contributor.author | Luetic, Geraldine | - |
dc.contributor.author | Tkachuk, Veronica A. | - |
dc.contributor.author | Miguez, Jimena | - |
dc.contributor.author | Diaz de Bedoya, Fernando Hamuy | - |
dc.contributor.author | Goiry, Lorna Galleguillos | - |
dc.contributor.author | Ramirez Sanchez, Nicia E. | - |
dc.contributor.author | Burgos, Marcos | - |
dc.contributor.author | Steinberg, Judith | - |
dc.contributor.author | Balbuena, Maria E. | - |
dc.contributor.author | Monterrey Alvarez, Priscilla | - |
dc.contributor.author | Lopez, Pablo A. | - |
dc.contributor.author | Ysrraelit, Maria C. | - |
dc.contributor.author | Leon, Rosalba A. | - |
dc.contributor.author | Cohen, Aron Benzadon | - |
dc.contributor.author | Gracia, Fernando | - |
dc.contributor.author | Molina, Omaira | - |
dc.contributor.author | Casas, Magdalena | - |
dc.contributor.author | Deri, Norma H. | - |
dc.contributor.author | Pappolla, Agustin | - |
dc.contributor.author | Patrucco, Liliana | - |
dc.contributor.author | Cristiano, Edgardo | - |
dc.contributor.author | Tavolini, Dario | - |
dc.contributor.author | Nadur, Debora | - |
dc.contributor.author | Granda, Ana M. Toral | - |
dc.contributor.author | Weiser, Roberto | - |
dc.contributor.author | Cassara, Fatima Pagani | - |
dc.contributor.author | Sinay, Vladimiro | - |
dc.contributor.author | Carcamo Rodriguez, Claudia | - |
dc.contributor.author | Lazaro, Luciana G. | - |
dc.contributor.author | Menichini, Maria L. | - |
dc.contributor.author | Piedrabuena, Raul | - |
dc.contributor.author | Orozco Escobar, Geraldine | - |
dc.contributor.author | Carra, Adriana | - |
dc.contributor.author | Chertcoff, Anibal | - |
dc.contributor.author | Santos Pujols, Biany | - |
dc.contributor.author | Vrech, Carlos | - |
dc.contributor.author | Tarulla, Adriana | - |
dc.contributor.author | Carvajal, Rene | - |
dc.contributor.author | Mainella, Carolina | - |
dc.contributor.author | Becker, Jefferson | - |
dc.contributor.author | PEETERS, Liesbet | - |
dc.contributor.author | Walton, Clare | - |
dc.contributor.author | Alonso Serena, Marina | - |
dc.contributor.author | Nunez, Sebastian | - |
dc.contributor.author | Rojas, Juan, I | - |
dc.date.accessioned | 2021-09-15T09:43:04Z | - |
dc.date.available | 2021-09-15T09:43:04Z | - |
dc.date.issued | 2021 | - |
dc.date.submitted | 2021-09-09T13:13:18Z | - |
dc.identifier.citation | Multiple sclerosis and related disorders (Print), 51 (Art N° 102886) | - |
dc.identifier.uri | http://hdl.handle.net/1942/35376 | - |
dc.description.abstract | Background: There is no data regarding COVID-19 in Multiple Sclerosis (MS) and neuromyelitis optica spectrum disorder (NMOSD) patients in Latin America. Objective: The objective of this study was to describe the clinical characteristics and outcomes of patients included in RELACOEM, a LATAM registry of MS and NMOSD patients infected with COVID-19. Methods: RELACOEM is a longitudinal, strictly observational registry of MS and NMOSD patients who suffer COVID-19 and Dengue in LATAM. Inclusion criteria to the registry were either: (1) a biologically confirmed COVID-19 diagnosis based on a positive result of a COVID-19 polymerase chain reaction (PCR) test on a naso-pharyngeal swab; or (2) COVID-19-typical symptoms (triad of cough, fever, and asthenia) in an epidemic zone of COVID-19. Descriptive statistics were performed on demographic and clinical variables. The cohort was later stratified for MS and NMOSD and univariate and multivariate logistic regression analysis was performed to identify variables associated with hospitalizations/intensive critical units (ICU) admission. Results: 145 patients were included in the registry from 15 countries and 51 treating physicians. A total of 129 (89%) were MS patients and 16 (11%) NMOSD. 81.4% patients had confirmed COVID-19 and 18.6% were suspected cases. 23 (15.8%) patients were hospitalized, 9 (6.2%) required ICU and 5 (3.4 %) died due to COVID-19. In MS patients, greater age (OR 1.17, 95% CI 1.05 - 1.25) and disease duration (OR 1.39, 95%CI 1.14-1.69) were associated with hospitalization/ICU. In NMOSD patients, a greater age (54.3 vs. 36 years, p=<0.001), increased EDSS (5.5 vs 2.9, p=0.0012) and disease duration (18.5 vs. 10.3 years, p=0.001) were significantly associated with hospitalization/ICU. Conclusion: we found that in MS patients, age and disease duration was associated with hospitalization and ICU admission requirement, while age, disease duration and EDSS was associated in NMOSD. | - |
dc.description.sponsorship | The authors thank everyone who actively participated in any of the teleconferences, webinars, and task force meetings. We would like to thank all the MS patients and healthcare professionals who already contributed to the different data collection efforts. | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCI LTD | - |
dc.rights | 2021 Elsevier B.V. All rights reserved. | - |
dc.subject.other | multiple sclerosis | - |
dc.subject.other | NMOSD | - |
dc.subject.other | COVID-19 | - |
dc.subject.other | registries | - |
dc.subject.other | Latin America | - |
dc.title | COVID-19 in multiple sclerosis and neuromyelitis optica spectrum disorder patients in Latin America COVID-19 in MS and NMOSD patients in LATAM | - |
dc.type | Journal Contribution | - |
dc.identifier.volume | 51 | - |
local.format.pages | 7 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Alonso, R (corresponding author), Univ Buenos Aires, Fac Med, Hosp Ramos Mejia, Ctr Univ Esclemsis Multiple CUEM, Urquiza 609,C1221 ADC, Caba, Argentina. | - |
local.publisher.place | THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.bibliographicCitation.artnr | 102886 | - |
dc.identifier.doi | 10.1016/j.msard.2021.102886 | - |
dc.identifier.isi | WOS:000689354300013 | - |
local.provider.type | wosris | - |
local.uhasselt.uhpub | yes | - |
local.description.affiliation | [Alonso, Ricardo] Hosp Ramos Mejia, Ctr Univ Esclerosis Multiple, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Alonso, Ricardo; Silva, Berenice; Garcea, Orlando; Lazaro, Luciana G.] Hosp Univ Sanatorio Guemes, Serv Neurol, Caba, Argentina. | - |
local.description.affiliation | [Correa Diaz, Patricio E.] Hosp Carlos Andrade Main, Quito, Ecuador. | - |
local.description.affiliation | [dos Passos, Giordani Rodrigues; Becker, Jefferson] Pontificia Univ Catolica Rio Grande do Sul, Hosp Sao Lucas, Porto Alegre, RS, Brazil. | - |
local.description.affiliation | [Ramirez Navarro, Deyanira A.] Hosp Docente Padre Billini, Santo Domingo, Dominican Rep. | - |
local.description.affiliation | [Garcia Valle, Luis A.] Hosp Mil Escuela Managua, Managua, Nicaragua. | - |
local.description.affiliation | [Rodriguez Salinas, Luis C.] Inst Hondureno Seguridad Social, Comayagua, Honduras. | - |
local.description.affiliation | [Negrotto, Laura; Ysrraelit, Maria C.] FLENI, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Luetic, Geraldine] Inst Neurociencias Rosario, Rosario, Argentina. | - |
local.description.affiliation | [Tkachuk, Veronica A.; Balbuena, Maria E.] Hosp Clin Jose San Martin, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Miguez, Jimena; Pappolla, Agustin; Patrucco, Liliana; Alonso Serena, Marina] Hosp Italian Buenos Aires, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Diaz de Bedoya, Fernando Hamuy] Hosp IMT, Dept Neurol, Asuncion, Paraguay. | - |
local.description.affiliation | [Diaz de Bedoya, Fernando Hamuy] Dept Neurol Diagnost Codas Thompson, Asuncion, Paraguay. | - |
local.description.affiliation | [Goiry, Lorna Galleguillos] Clin Alemana Santiago, Santiago, Chile. | - |
local.description.affiliation | [Ramirez Sanchez, Nicia E.] Hosp Dr Mario C Rivas San Pedro Sula, San Pedro Sula, Honduras. | - |
local.description.affiliation | [Burgos, Marcos] Hosp San Bernardo, Salta, Argentina. | - |
local.description.affiliation | [Steinberg, Judith; Carra, Adriana; Chertcoff, Anibal] Hosp Britan Buenos Aires, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Monterrey Alvarez, Priscilla] Hosp San Rafael, Alajuela, Costa Rica. | - |
local.description.affiliation | [Lopez, Pablo A.] Hosp Aleman Buenos Aires, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Cohen, Aron Benzadon] MD Complejo Hosp CSS, Panama City, Panama. | - |
local.description.affiliation | [Gracia, Fernando] Hosp Santo Tomas, Panama City, Panama. | - |
local.description.affiliation | [Molina, Omaira] Policlin Maracaibo, Maracaibo, Venezuela. | - |
local.description.affiliation | [Casas, Magdalena] Hosp JM Ramos Mejia, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Deri, Norma H.] Diabaid, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Cristiano, Edgardo; Rojas, Juan, I] Ctr Esclerosis Multiple Buenos Aires, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Tavolini, Dario] INECO Neurociencias Orono, Rosario, Argentina. | - |
local.description.affiliation | [Nadur, Debora] Hosp Clin Buenos Aires, Hosp Naval, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Granda, Ana M. Toral] Hosp Jose Carrasco Arteaga, Cuenca, Ecuador. | - |
local.description.affiliation | [Weiser, Roberto] Hosp Horacio Oduber, Caya Punta Brabo, Aruba. | - |
local.description.affiliation | [Cassara, Fatima Pagani] Hosp Univ Austral, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Cassara, Fatima Pagani; Sinay, Vladimiro] Fdn Favaloro, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Carcamo Rodriguez, Claudia] Univ Catolica Chile, Santiago, Chile. | - |
local.description.affiliation | [Menichini, Maria L.] Sanatorio Britan Rosario, Rosario, Argentina. | - |
local.description.affiliation | [Piedrabuena, Raul] Clin Reina Fabiola, Cordoba, Argentina. | - |
local.description.affiliation | [Piedrabuena, Raul] Inst Lennox, Cordoba, Argentina. | - |
local.description.affiliation | [Orozco Escobar, Geraldine] Hosp Patrocinio P Ruiz, San Cristobal, Venezuela. | - |
local.description.affiliation | [Santos Pujols, Biany] Hosp Reg Univ Jose Ma Cabral & Baez, Cordoba, Argentina. | - |
local.description.affiliation | [Vrech, Carlos] Sanatorio Allende, Cordoba, Argentina. | - |
local.description.affiliation | [Tarulla, Adriana] Hosp Agudos P Pinero, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Carvajal, Rene] Hosp Univ Nacl Colombia, Bogota, Colombia. | - |
local.description.affiliation | [Mainella, Carolina] Hosp Espanol Rosario, Rosario, Argentina. | - |
local.description.affiliation | [Peeters, Liesbet M.] Hasselt Univ, Univ Multiple Sclerosis Ctr, Hasselt, Belgium. | - |
local.description.affiliation | [Peeters, Liesbet M.] Hasselt Univ, Biomed Res Inst, Hasselt, Belgium. | - |
local.description.affiliation | [Peeters, Liesbet M.] Hasselt Univ, Data Sci Inst, Hasselt, Belgium. | - |
local.description.affiliation | [Walton, Clare] MS Int Federat, London, England. | - |
local.description.affiliation | [Nunez, Sebastian] Infect Dis Unit Sanatorio Guemes, Buenos Aires, DF, Argentina. | - |
local.description.affiliation | [Rojas, Juan, I] Hosp Univ CEMIC, Serv Neurol, Buenos Aires, DF, Argentina. | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.accessRights | Open Access | - |
item.fullcitation | Alonso, Ricardo; Silva, Berenice; Garcea, Orlando; Correa Diaz, Patricio E.; dos Passos, Giordani Rodrigues; Ramirez Navarro, Deyanira A.; Garcia Valle, Luis A.; Rodriguez Salinas, Luis C.; Negrotto, Laura; Luetic, Geraldine; Tkachuk, Veronica A.; Miguez, Jimena; Diaz de Bedoya, Fernando Hamuy; Goiry, Lorna Galleguillos; Ramirez Sanchez, Nicia E.; Burgos, Marcos; Steinberg, Judith; Balbuena, Maria E.; Monterrey Alvarez, Priscilla; Lopez, Pablo A.; Ysrraelit, Maria C.; Leon, Rosalba A.; Cohen, Aron Benzadon; Gracia, Fernando; Molina, Omaira; Casas, Magdalena; Deri, Norma H.; Pappolla, Agustin; Patrucco, Liliana; Cristiano, Edgardo; Tavolini, Dario; Nadur, Debora; Granda, Ana M. Toral; Weiser, Roberto; Cassara, Fatima Pagani; Sinay, Vladimiro; Carcamo Rodriguez, Claudia; Lazaro, Luciana G.; Menichini, Maria L.; Piedrabuena, Raul; Orozco Escobar, Geraldine; Carra, Adriana; Chertcoff, Anibal; Santos Pujols, Biany; Vrech, Carlos; Tarulla, Adriana; Carvajal, Rene; Mainella, Carolina; Becker, Jefferson; PEETERS, Liesbet; Walton, Clare; Alonso Serena, Marina; Nunez, Sebastian & Rojas, Juan, I (2021) COVID-19 in multiple sclerosis and neuromyelitis optica spectrum disorder patients in Latin America COVID-19 in MS and NMOSD patients in LATAM. In: Multiple sclerosis and related disorders (Print), 51 (Art N° 102886). | - |
item.validation | ecoom 2022 | - |
item.contributor | Alonso, Ricardo | - |
item.contributor | Silva, Berenice | - |
item.contributor | Garcea, Orlando | - |
item.contributor | Correa Diaz, Patricio E. | - |
item.contributor | dos Passos, Giordani Rodrigues | - |
item.contributor | Ramirez Navarro, Deyanira A. | - |
item.contributor | Garcia Valle, Luis A. | - |
item.contributor | Rodriguez Salinas, Luis C. | - |
item.contributor | Negrotto, Laura | - |
item.contributor | Luetic, Geraldine | - |
item.contributor | Tkachuk, Veronica A. | - |
item.contributor | Miguez, Jimena | - |
item.contributor | Diaz de Bedoya, Fernando Hamuy | - |
item.contributor | Goiry, Lorna Galleguillos | - |
item.contributor | Ramirez Sanchez, Nicia E. | - |
item.contributor | Burgos, Marcos | - |
item.contributor | Steinberg, Judith | - |
item.contributor | Balbuena, Maria E. | - |
item.contributor | Monterrey Alvarez, Priscilla | - |
item.contributor | Lopez, Pablo A. | - |
item.contributor | Ysrraelit, Maria C. | - |
item.contributor | Leon, Rosalba A. | - |
item.contributor | Cohen, Aron Benzadon | - |
item.contributor | Gracia, Fernando | - |
item.contributor | Molina, Omaira | - |
item.contributor | Casas, Magdalena | - |
item.contributor | Deri, Norma H. | - |
item.contributor | Pappolla, Agustin | - |
item.contributor | Patrucco, Liliana | - |
item.contributor | Cristiano, Edgardo | - |
item.contributor | Tavolini, Dario | - |
item.contributor | Nadur, Debora | - |
item.contributor | Granda, Ana M. Toral | - |
item.contributor | Weiser, Roberto | - |
item.contributor | Cassara, Fatima Pagani | - |
item.contributor | Sinay, Vladimiro | - |
item.contributor | Carcamo Rodriguez, Claudia | - |
item.contributor | Lazaro, Luciana G. | - |
item.contributor | Menichini, Maria L. | - |
item.contributor | Piedrabuena, Raul | - |
item.contributor | Orozco Escobar, Geraldine | - |
item.contributor | Carra, Adriana | - |
item.contributor | Chertcoff, Anibal | - |
item.contributor | Santos Pujols, Biany | - |
item.contributor | Vrech, Carlos | - |
item.contributor | Tarulla, Adriana | - |
item.contributor | Carvajal, Rene | - |
item.contributor | Mainella, Carolina | - |
item.contributor | Becker, Jefferson | - |
item.contributor | PEETERS, Liesbet | - |
item.contributor | Walton, Clare | - |
item.contributor | Alonso Serena, Marina | - |
item.contributor | Nunez, Sebastian | - |
item.contributor | Rojas, Juan, I | - |
crisitem.journal.issn | 2211-0348 | - |
crisitem.journal.eissn | 2211-0356 | - |
Appears in Collections: | Research publications |
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1-s20-S221103482100153X-main.pdf | Published version | 935.43 kB | Adobe PDF | View/Open |
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