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http://hdl.handle.net/1942/3654
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DC Field | Value | Language |
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dc.contributor.author | CUYPERS, Y | - |
dc.contributor.author | McConaghey, P. | - |
dc.contributor.author | STEELS, Paul | - |
dc.date.accessioned | 2007-11-29T11:52:50Z | - |
dc.date.available | 2007-11-29T11:52:50Z | - |
dc.date.issued | 1993 | - |
dc.identifier.citation | RENAL PHYSIOLOGY AND BIOCHEMISTRY, 16(6). p. 325-332 | - |
dc.identifier.issn | 1011-6524 | - |
dc.identifier.uri | http://hdl.handle.net/1942/3654 | - |
dc.description.abstract | Taking advantage of the particular renal vascular arrangement in cocks, angiotensin II was injected (0.12-0.96 mu g/min) into the portal system of one kidney in order to increase the angiotensin-II concentration in the physiological nanomolar range at the level. of the renal tubules. Angiotensin II induced an increase in blood pressure of 5% and a bilateral rise in glomerular filtration rate and effective renal plasma now of 28 and 22%, respectively. The urine volume increased five times on the infused side and three times on the control side. The Na+ excretion increased 14 times on the infused side and only seven times on the control side. During angiotensin infusion, the fractional water excretion was 4.9% on the infused side and 2.9% on th e control side versus 1.1 and 1.2% during the control period. For the fractional Na+ excretion, the respective values were 2 and 1.2% versus 0.2 and 0.2% during the control period. The differences between the two kidneys demonstrate the direct tubular action of angiotensin II, inhibiting the tubular Na+ and water reabsorption at physiological nanomolar concentrations. Angiotensin seems thus to play an important intrarenal role. | - |
dc.language.iso | en | - |
dc.publisher | KARGER | - |
dc.subject.other | ANGIOTENSIN II; EFFECTIVE RENAL PLASMA FLOW; GLOMERULAR FILTRATION RATE; K+ EXCRETION; NA+ EXCRETION; RENAL TUBULAR TRANSPORT; SPERBER TECHNIQUE | - |
dc.title | The direct renal tubular effect of angiotensin-II in chicken | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 332 | - |
dc.identifier.issue | 6 | - |
dc.identifier.spage | 325 | - |
dc.identifier.volume | 16 | - |
local.format.pages | 8 | - |
dc.description.notes | LIMBURGS UNIV CENTRUM,FYSIOL LAB,B-3390 DIEPENBEEK,BELGIUM. | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.bibliographicCitation.oldjcat | A1 | - |
dc.identifier.isi | A1993MJ67300004 | - |
item.fulltext | No Fulltext | - |
item.contributor | CUYPERS, Y | - |
item.contributor | McConaghey, P. | - |
item.contributor | STEELS, Paul | - |
item.accessRights | Closed Access | - |
item.fullcitation | CUYPERS, Y; McConaghey, P. & STEELS, Paul (1993) The direct renal tubular effect of angiotensin-II in chicken. In: RENAL PHYSIOLOGY AND BIOCHEMISTRY, 16(6). p. 325-332. | - |
Appears in Collections: | Research publications |
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