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Title: | Schistocerca neuropeptides – An update | Authors: | Ragionieri, Lapo VERDONCK, Rik Verlinden, Heleen Marchal, Elisabeth Vanden Broeck, Jozef Predel, Reinhard |
Issue Date: | 2022 | Publisher: | PERGAMON-ELSEVIER SCIENCE LTD | Source: | JOURNAL OF INSECT PHYSIOLOGY, 136 (Art N° 104326) | Abstract: | We compiled a comprehensive list of 67 precursor genes encoding neuropeptides and neuropeptide-like peptides using the Schistocerca gregaria genome and several transcriptome datasets. 11 of these 67 precursor genes have alternative transcripts, bringing the total number of S. gregaria precursors identified in this study to 81. Based on this precursor information, we used different mass spectrometry approaches to identify the putative mature, bioactive peptides processed in the nervous system of S. gregaria. The thereby generated dataset for S. gregaria confirms significant conservation of the entire neuropeptidergic gene set typical of insects and also contains precursors typical of Polyneoptera only. This is in striking contrast to the substantial losses of peptidergic systems in some holometabolous species. The neuropeptidome of S. gregaria, apart from species-specific sequences within the known range of variation, is quite similar to that of Locusta migratoria and even to that of less closely related Polyneoptera. With the S. gregaria peptidomics data presented here, we have thus generated a very useful source of information that could also be relevant for the study of other polyneopteran species. | Notes: | Ragionieri, L; Predel, R (corresponding author), Univ Cologne, Dept Biol, Inst Zool, Zulpicher Str 47b, D-50674 Cologne, Germany.; Vanden Broeck, J (corresponding author), Katholieke Univ Leuven, Zool Inst, Div Anim Physiol & Neurobiol, B-3000 Leuven, Belgium. lapo.ragionieri@unikoeln.de; jozef.vandenbroeck@kuleuven.be; rpredel@uni-koeln.de and to JVB], and the Research Foundation of Flanders (FWO) [G0F2417N, G090919N] to JVB. |
Keywords: | Locust;Mass spectrometry;Peptidomics;Genome;Transcriptome | Document URI: | http://hdl.handle.net/1942/37403 | ISSN: | 0022-1910 | e-ISSN: | 1879-1611 | DOI: | 10.1016/j.jinsphys.2021.104326 | ISI #: | WOS:000787580200003 | Rights: | 2021 Elsevier Ltd. All rights reserved. | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2023 |
Appears in Collections: | Research publications |
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Schistocerca neuropeptides – An update.pdf Restricted Access | Published version | 3.46 MB | Adobe PDF | View/Open Request a copy |
Ragionieri et al.pdf | Peer-reviewed author version | 2.62 MB | Adobe PDF | View/Open |
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