Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/37473
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dc.contributor.authorVrijheid, Martine-
dc.contributor.authorBasagana, Xavier-
dc.contributor.authorGonzalez, Juan R.-
dc.contributor.authorJaddoe, Vincent W. V.-
dc.contributor.authorJensen, Genon-
dc.contributor.authorKeun, Hector C.-
dc.contributor.authorMcEachan, Rosemary R. C.-
dc.contributor.authorPorcel, Joana-
dc.contributor.authorSiroux, Valerie-
dc.contributor.authorSwertz, Morris A.-
dc.contributor.authorThomsen, Cathrine-
dc.contributor.authorAasvang, Gunn Marit-
dc.contributor.authorAndrusaityte, Sandra-
dc.contributor.authorAngeli, Karine-
dc.contributor.authorAvraam, Demetris-
dc.contributor.authorBallester, Ferran-
dc.contributor.authorBurton, Paul-
dc.contributor.authorBustamante, Mariona-
dc.contributor.authorCasas, Maribel-
dc.contributor.authorChatzi, Leda-
dc.contributor.authorChevrier, Cecile-
dc.contributor.authorCingotti, Natacha-
dc.contributor.authorConti, David-
dc.contributor.authorCrepet, Amelie-
dc.contributor.authorDadvand, Payam-
dc.contributor.authorDuijts, Liesbeth-
dc.contributor.authorvan Enckevort, Esther-
dc.contributor.authorEsplugues, Ana-
dc.contributor.authorFossati, Serena-
dc.contributor.authorGarlantezec, Ronan-
dc.contributor.authorGomez Roig, Maria Dolores-
dc.contributor.authorGrazuleviciene, Regina-
dc.contributor.authorGuetzkow, Kristine B.-
dc.contributor.authorGuxens, Monica-
dc.contributor.authorHaakma, Sido-
dc.contributor.authorHessel, Ellen V. S.-
dc.contributor.authorHoyles, Lesley-
dc.contributor.authorHyde, Eleanor-
dc.contributor.authorKlanova, Jana-
dc.contributor.authorvan Klaveren, Jacob D.-
dc.contributor.authorKortenkamp, Andreas-
dc.contributor.authorLe Brusquet, Laurent-
dc.contributor.authorLeenen, Ivonne-
dc.contributor.authorLertxundi, Aitana-
dc.contributor.authorLertxundi, Nerea-
dc.contributor.authorLionis, Christos-
dc.contributor.authorLlop, Sabrina-
dc.contributor.authorLopez-Espinosa, Maria-Jose-
dc.contributor.authorLyon-Caen, Sarah-
dc.contributor.authorMaitre, Lea-
dc.contributor.authorMason, Dan-
dc.contributor.authorMathy, Sandrine-
dc.contributor.authorMazarico, Edurne-
dc.contributor.authorNAWROT, Tim-
dc.contributor.authorNieuwenhuijsen, Mark-
dc.contributor.authorOrtiz, Rodney-
dc.contributor.authorPedersen, Marie-
dc.contributor.authorPerello, Josep-
dc.contributor.authorPerez-Cruz, Miriam-
dc.contributor.authorPhilippat, Claire-
dc.contributor.authorPiler, Pavel-
dc.contributor.authorPizzi, Costanza-
dc.contributor.authorQuentin, Joane-
dc.contributor.authorRichiardi, Lorenzo-
dc.contributor.authorRODRIGUEZ, Adrian-
dc.contributor.authorRoumeliotaki, Theano-
dc.contributor.authorSabin Capote, Jose Manuel-
dc.contributor.authorSantiago, Leonardo-
dc.contributor.authorSantos, Susana-
dc.contributor.authorSiskos, Alexandros P.-
dc.contributor.authorStrandberg-Larsen, Katrine-
dc.contributor.authorStratakis, Nikos-
dc.contributor.authorSunyer, Jordi-
dc.contributor.authorTenenhaus, Arthur-
dc.contributor.authorVafeiadi, Marina-
dc.contributor.authorWilson, Rebecca C.-
dc.contributor.authorWright, John-
dc.contributor.authorYANG, Tiffany-
dc.contributor.authorSlama, Remy-
dc.date.accessioned2022-06-09T10:34:26Z-
dc.date.available2022-06-09T10:34:26Z-
dc.date.issued2021-
dc.date.submitted2022-05-19T09:02:44Z-
dc.identifier.citationEnvironmental Epidemiology, 5 (5) (Art N° e166)-
dc.identifier.urihttp://hdl.handle.net/1942/37473-
dc.description.abstractEarly life stages are vulnerable to environmental hazards and present important windows of opportunity for lifelong disease prevention. This makes early life a relevant starting point for exposome studies. The Advancing Tools for Human Early Lifecourse Exposome Research and Translation (ATHLETE) project aims to develop a toolbox of exposome tools and a Europe-wide exposome cohort that will be used to systematically quantify the effects of a wide range of community- and individual-level environmental risk factors on mental, cardiometabolic, and respiratory health outcomes and associated biological pathways, longitudinally from early pregnancy through to adolescence. Exposome tool and data development include as follows: (1) a findable, accessible, interoperable, reusable (FAIR) data infrastructure for early life exposome cohort data, including 16 prospective birth cohorts in 11 European countries; (2) targeted and nontargeted approaches to measure a wide range of environmental exposures (urban, chemical, physical, behavioral, social); (3) advanced statistical and toxicological strategies to analyze complex multidimensional exposome data; (4) estimation of associations between the exposome and early organ development, health trajectories, and biological (metagenomic, metabolomic, epigenetic, aging, and stress) pathways; (5) intervention strategies to improve early life urban and chemical exposomes, co-produced with local communities; and (6) child health impacts and associated costs related to the exposome. Data, tools, and results will be assembled in an openly accessible toolbox, which will provide great opportunities for researchers, policy-makers, and other stakeholders, beyond the duration of the project. ATHLETE'S results will help to better understand and prevent health damage from environmental exposures and their mixtures from the earliest parts of the life course onward.-
dc.description.sponsorshipThis project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement number 874583—the Advancing Tools for Human Early Lifecourse Exposome Research and Translation (ATHLETE) project. This publication reflects only the authors’ view and the European Commission is not responsible for any use that may be made of the information it contains. Dr. Dadvand is funded by a Ramón y Cajal fellowship (RYC2012-10995) awarded by the Spanish Ministry of Economy and Finance. Drs. Casas and Guxens are funded by the Instituto de Salud Carlos III (MS16/00128, CPII18/00018). Drs. Chatzi and Conti were supported by the National Institute of Environmental Health Sciences (R21ES029681, R01ES029944, R01ES030364, R01ES030691, and P30ES007048). Additional funding from National Institutes of Health supported Dr. Conti (P01CA196569, R01CA140561) and Dr. Stratakis (P30DK048522). Investigators Drs. McEachan and Wright receive funding from the National Institute for Health Research under its Applied Research Collaboration Yorkshire and Humber. Dr. Jaddoe received funding from a Consolidator Grant from the European Research Council (ERC-2014-CoG-648916). Dr. Duijts received funding from the European Union’s Horizon 2020 co-funded programme European Research Area Net on Biomarkers for Nutrition and Health (European Research Area Healthy Diet for a Healthy Life) (Early life programming of childhood health project [number 696295; 2017], ZonMW, The Netherlands [number 529051014; 2017]). Dr. Guxens received funding from the Agence Nationale de Securite Sanitaire de l’Alimentation de l’Environnement et du Travail (EST-18 RF-25). The views expressed are those of the author(s) and not necessarily those of the National Institute for Health Research or the Department of Health and Social Care.-
dc.language.isoen-
dc.publisherLIPPINCOTT WILLIAMS & WILKINS-
dc.rights© 2021 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The Environmental Epidemiology. All rights reserved. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.-
dc.subject.otherExposome-
dc.subject.otherEarly life-
dc.subject.otherExposure assessment-
dc.subject.otherChild health-
dc.subject.otherAdolescent health-
dc.titleAdvancing tools for human early lifecourse exposome research and translation (ATHLETE)-
dc.typeJournal Contribution-
dc.identifier.issue5-
dc.identifier.volume5-
local.format.pages15-
local.bibliographicCitation.jcatA1-
dc.description.notesVrijheid, M (corresponding author), Inst Global Hlth, ISGlobal, C Doctor Aiguader 88, Barcelona 08003, Spain.-
dc.description.notesmartine.vrijheid@isglobal.org-
local.publisher.placeTWO COMMERCE SQ, 2001 MARKET ST, PHILADELPHIA, PA 19103 USA-
local.type.refereedRefereed-
local.type.specifiedReview-
local.bibliographicCitation.artnre166-
local.type.programmeH2020-
local.relation.h2020874583-
dc.identifier.doi10.1097/EE9.0000000000000166-
dc.identifier.isiWOS:000784742100005-
dc.contributor.orcidBasagana, Xavier/0000-0002-8457-1489; Stratakis,-
dc.contributor.orcidNikos/0000-0003-4613-0989; Yang, Tiffany/0000-0003-4549-7850;-
dc.contributor.orcidAndrusaityte, Sandra/0000-0002-4309-0208; McEachan,-
dc.contributor.orcidRosemary/0000-0003-1302-6675; Hoyles, Lesley/0000-0002-6418-342X;-
dc.contributor.orcidLERTXUNDI MANTEROLA, AITANA/0000-0002-9421-6237; Lopez-Espinosa,-
dc.contributor.orcidMaria-Jose/0000-0003-1202-8740; Santos, Susana/0000-0003-0613-3181;-
dc.contributor.orcidNawrot, Tim/0000-0002-3583-3593; Wilson, Becca/0000-0003-2294-593X-
local.provider.typewosris-
local.description.affiliation[Vrijheid, Martine; Basagana, Xavier; Gonzalez, Juan R.; Porcel, Joana; Bustamante, Mariona; Casas, Maribel; Dadvand, Payam; Fossati, Serena; Guxens, Monica; Maitre, Lea; Nieuwenhuijsen, Mark; Ortiz, Rodney; Stratakis, Nikos; Sunyer, Jordi] AISGlobal, Barcelona, Spain.-
local.description.affiliation[Vrijheid, Martine; Basagana, Xavier; Gonzalez, Juan R.; Porcel, Joana; Ballester, Ferran; Bustamante, Mariona; Casas, Maribel; Dadvand, Payam; Esplugues, Ana; Fossati, Serena; Guxens, Monica; Lertxundi, Aitana; Llop, Sabrina; Lopez-Espinosa, Maria-Jose; Maitre, Lea; Nieuwenhuijsen, Mark; Ortiz, Rodney; Sunyer, Jordi] Spanish Consortium Res Epidemiol & Publ Hlth CIB, Madrid, Spain.-
local.description.affiliation[Guxens, Monica] Univ Pompeu Fabra, Barcelona, Spain.-
local.description.affiliation[Jaddoe, Vincent W. V.; Duijts, Liesbeth; Santos, Susana] Erasmus Univ, Generat R Study Grp, Med Ctr, Rotterdam, Netherlands.-
local.description.affiliation[Jaddoe, Vincent W. V.; Duijts, Liesbeth; Santos, Susana] Erasmus Univ, Dept Pediat, Med Ctr, Rotterdam, Netherlands.-
local.description.affiliation[Jensen, Genon; Cingotti, Natacha; Leenen, Ivonne] Health Environm Alliance HEAL, Brussels, Belgium.-
local.description.affiliation[Keun, Hector C.; Siskos, Alexandros P.] Imperial Coll London, Dept Surg Canc & Dept Metab, Digest Reprod, London, England.-
local.description.affiliation[McEachan, Rosemary R. C.; Mason, Dan; Wright, John; Yang, Tiffany] Bradford Teaching Hosp NHS Fdn Trust, Bradford Inst Hlth Res, Bradford, W Yorkshire, England.-
local.description.affiliation[Siroux, Valerie; Lyon-Caen, Sarah; Philippat, Claire; Quentin, Joane; Slama, Remy] Univ Grenoble Alpes, CNRS, IAB Inst Adv Biosciences Joint Res Ctr, INSERM, Grenoble, France.-
local.description.affiliation[Swertz, Morris A.; van Enckevort, Esther; Haakma, Sido; Hyde, Eleanor] Univ Groningen, Univ Med Ctr Groningen, Genom Coordinat Ctr, Groningen, Netherlands.-
local.description.affiliation[Swertz, Morris A.; van Enckevort, Esther; Haakma, Sido; Hyde, Eleanor] Univ Groningen, Univ Med Ctr Groningen, Dept Genet, Groningen, Netherlands.-
local.description.affiliation[Thomsen, Cathrine; Aasvang, Gunn Marit; Guetzkow, Kristine B.] Norwegian Inst Publ Hlth, Dept Environm Hlth, Oslo, Norway.-
local.description.affiliation[Andrusaityte, Sandra; Grazuleviciene, Regina] Vytautas Magnus Univ, Dept Environm Sci, Kaunas, Lithuania.-
local.description.affiliation[Angeli, Karine; Crepet, Amelie] French Agcy Food Environm & Occupat Hlth & Safety, Risk Assessment Dept, Maisons Alfort, France.-
local.description.affiliation[Avraam, Demetris; Burton, Paul] Newcastle Univ, Populat Hlth Sci Inst, Newcastle, NSW, Australia.-
local.description.affiliation[Ballester, Ferran; Esplugues, Ana; Llop, Sabrina; Lopez-Espinosa, Maria-Jose] FISABIO Univ Jaume Univ Valencia, Epidemiol & Environm Hlth Joint Res Unit, Valencia, Spain.-
local.description.affiliation[Ballester, Ferran; Esplugues, Ana; Lopez-Espinosa, Maria-Jose] Univ Valencia, Fac Nursing & Chiropody, Valencia, Spain.-
local.description.affiliation[Chatzi, Leda; Conti, David; Stratakis, Nikos] Univ Southern Calif, Keck Sch Med, Dept Prevent Med, Los Angeles, CA USA.-
local.description.affiliation[Chevrier, Cecile] Univ Rennes, Irset Inst Rech sante, INSERM, EHESP,UMRS 1085, Rennes, France.-
local.description.affiliation[Garlantezec, Ronan] Univ Rennes, Irset Inst Rech sante, TCHU Rennes, INSERM,UMR S 1085, Rennes, France.-
local.description.affiliation[Gomez Roig, Maria Dolores; Mazarico, Edurne; Perez-Cruz, Miriam] Inst Recerca Sant Joan Deu IR SJD, Barcelona, Spain.-
local.description.affiliation[Gomez Roig, Maria Dolores; Mazarico, Edurne; Perez-Cruz, Miriam] Inst Salud Carlos III ISCIII, Maternal & Child Hlth & Dev Network II SAMID II, Madrid, Spain.-
local.description.affiliationHosp San Juan Dios, BCNatal Barcelona Ctr Maternal Fetal & Neonatal, Barcelona, Spain.-
local.description.affiliation[Guxens, Monica] Univ Med Ctr, Dept Child & Adolescence Psychiat, Erasmus MC, Rotterdam, Netherlands.-
local.description.affiliation[Hessel, Ellen V. S.; van Klaveren, Jacob D.] Nat Inst Publ Hlth & Environm RIVM, Bilthoven, Netherlands.-
local.description.affiliation[Hoyles, Lesley] Nottingham Trent Univ, Dept Biosci, Nottingham, England.-
local.description.affiliation[Klanova, Jana; Piler, Pavel] Masaryk Univ, RECETOX Ctr, Fac Sci, Brno, Czech Republic.-
local.description.affiliation[Kortenkamp, Andreas] Brunel Univ London, Coll Hlth Med & Life Sci, Uxbridge, Middx, England.-
local.description.affiliation[Le Brusquet, Laurent; Tenenhaus, Arthur] Univ Paris Saclay, CNRS, CentraleSupelec, Lab Signaux & Syst, Gif Sur Yvette, France.-
local.description.affiliation[Lertxundi, Aitana; Lertxundi, Nerea] Univ Basque Country UPV EHU, Bilbao, Spain.-
local.description.affiliation[Lertxundi, Aitana; Lertxundi, Nerea] Biodonostia Res Hlth Inst, Donostia San Sebastian, Spain.-
local.description.affiliation[Lionis, Christos; Roumeliotaki, Theano; Vafeiadi, Marina] Univ Crete, Sch Med, Dept Social Med, Iraklion, Greece.-
local.description.affiliation[Mathy, Sandrine] Univ Grenoble Alpes, CNRS, INRAE, Grenoble, France.-
local.description.affiliation[Nawrot, Tim] Hasselt Univ, Ctr Environm Sci, Hasselt, Belgium.-
local.description.affiliation[Nawrot, Tim] Leuven Univ, Ctr Hlth & Environm, Leuven, Belgium.-
local.description.affiliation[Pedersen, Marie; Strandberg-Larsen, Katrine] Univ Copenhagen, Dept Publ Hlth, Copenhagen, Denmark.-
local.description.affiliation[Perello, Josep; Rodriguez, Adrian; Sabin Capote, Jose Manuel; Santiago, Leonardo] Bettair Cities SL, Barcelona, Spain.-
local.description.affiliation[Pizzi, Costanza; Richiardi, Lorenzo] Univ Turin, Dept Med Sci, Canc Epidemiol Unit, Turin, Italy.-
local.description.affiliation[Wilson, Rebecca C.] Univ Liverpool, Dept Publ Hlth Policy & Syst, Liverpool, Merseyside, England.-
local.uhasselt.internationalyes-
item.validationvabb 2024-
item.fulltextWith Fulltext-
item.fullcitationVrijheid, Martine; Basagana, Xavier; Gonzalez, Juan R.; Jaddoe, Vincent W. V.; Jensen, Genon; Keun, Hector C.; McEachan, Rosemary R. C.; Porcel, Joana; Siroux, Valerie; Swertz, Morris A.; Thomsen, Cathrine; Aasvang, Gunn Marit; Andrusaityte, Sandra; Angeli, Karine; Avraam, Demetris; Ballester, Ferran; Burton, Paul; Bustamante, Mariona; Casas, Maribel; Chatzi, Leda; Chevrier, Cecile; Cingotti, Natacha; Conti, David; Crepet, Amelie; Dadvand, Payam; Duijts, Liesbeth; van Enckevort, Esther; Esplugues, Ana; Fossati, Serena; Garlantezec, Ronan; Gomez Roig, Maria Dolores; Grazuleviciene, Regina; Guetzkow, Kristine B.; Guxens, Monica; Haakma, Sido; Hessel, Ellen V. S.; Hoyles, Lesley; Hyde, Eleanor; Klanova, Jana; van Klaveren, Jacob D.; Kortenkamp, Andreas; Le Brusquet, Laurent; Leenen, Ivonne; Lertxundi, Aitana; Lertxundi, Nerea; Lionis, Christos; Llop, Sabrina; Lopez-Espinosa, Maria-Jose; Lyon-Caen, Sarah; Maitre, Lea; Mason, Dan; Mathy, Sandrine; Mazarico, Edurne; NAWROT, Tim; Nieuwenhuijsen, Mark; Ortiz, Rodney; Pedersen, Marie; Perello, Josep; Perez-Cruz, Miriam; Philippat, Claire; Piler, Pavel; Pizzi, Costanza; Quentin, Joane; Richiardi, Lorenzo; RODRIGUEZ, Adrian; Roumeliotaki, Theano; Sabin Capote, Jose Manuel; Santiago, Leonardo; Santos, Susana; Siskos, Alexandros P.; Strandberg-Larsen, Katrine; Stratakis, Nikos; Sunyer, Jordi; Tenenhaus, Arthur; Vafeiadi, Marina; Wilson, Rebecca C.; Wright, John; YANG, Tiffany & Slama, Remy (2021) Advancing tools for human early lifecourse exposome research and translation (ATHLETE). In: Environmental Epidemiology, 5 (5) (Art N° e166).-
item.accessRightsOpen Access-
item.contributorVrijheid, Martine-
item.contributorBasagana, Xavier-
item.contributorGonzalez, Juan R.-
item.contributorJaddoe, Vincent W. V.-
item.contributorJensen, Genon-
item.contributorKeun, Hector C.-
item.contributorMcEachan, Rosemary R. C.-
item.contributorPorcel, Joana-
item.contributorSiroux, Valerie-
item.contributorSwertz, Morris A.-
item.contributorThomsen, Cathrine-
item.contributorAasvang, Gunn Marit-
item.contributorAndrusaityte, Sandra-
item.contributorAngeli, Karine-
item.contributorAvraam, Demetris-
item.contributorBallester, Ferran-
item.contributorBurton, Paul-
item.contributorBustamante, Mariona-
item.contributorCasas, Maribel-
item.contributorChatzi, Leda-
item.contributorChevrier, Cecile-
item.contributorCingotti, Natacha-
item.contributorConti, David-
item.contributorCrepet, Amelie-
item.contributorDadvand, Payam-
item.contributorDuijts, Liesbeth-
item.contributorvan Enckevort, Esther-
item.contributorEsplugues, Ana-
item.contributorFossati, Serena-
item.contributorGarlantezec, Ronan-
item.contributorGomez Roig, Maria Dolores-
item.contributorGrazuleviciene, Regina-
item.contributorGuetzkow, Kristine B.-
item.contributorGuxens, Monica-
item.contributorHaakma, Sido-
item.contributorHessel, Ellen V. S.-
item.contributorHoyles, Lesley-
item.contributorHyde, Eleanor-
item.contributorKlanova, Jana-
item.contributorvan Klaveren, Jacob D.-
item.contributorKortenkamp, Andreas-
item.contributorLe Brusquet, Laurent-
item.contributorLeenen, Ivonne-
item.contributorLertxundi, Aitana-
item.contributorLertxundi, Nerea-
item.contributorLionis, Christos-
item.contributorLlop, Sabrina-
item.contributorLopez-Espinosa, Maria-Jose-
item.contributorLyon-Caen, Sarah-
item.contributorMaitre, Lea-
item.contributorMason, Dan-
item.contributorMathy, Sandrine-
item.contributorMazarico, Edurne-
item.contributorNAWROT, Tim-
item.contributorNieuwenhuijsen, Mark-
item.contributorOrtiz, Rodney-
item.contributorPedersen, Marie-
item.contributorPerello, Josep-
item.contributorPerez-Cruz, Miriam-
item.contributorPhilippat, Claire-
item.contributorPiler, Pavel-
item.contributorPizzi, Costanza-
item.contributorQuentin, Joane-
item.contributorRichiardi, Lorenzo-
item.contributorRODRIGUEZ, Adrian-
item.contributorRoumeliotaki, Theano-
item.contributorSabin Capote, Jose Manuel-
item.contributorSantiago, Leonardo-
item.contributorSantos, Susana-
item.contributorSiskos, Alexandros P.-
item.contributorStrandberg-Larsen, Katrine-
item.contributorStratakis, Nikos-
item.contributorSunyer, Jordi-
item.contributorTenenhaus, Arthur-
item.contributorVafeiadi, Marina-
item.contributorWilson, Rebecca C.-
item.contributorWright, John-
item.contributorYANG, Tiffany-
item.contributorSlama, Remy-
crisitem.journal.eissn2474-7882-
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