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http://hdl.handle.net/1942/38086
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DC Field | Value | Language |
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dc.contributor.author | van Oorschot, Eva | - |
dc.contributor.author | KOC, Ozgur | - |
dc.contributor.author | Lashof, Astrid Ml Oude | - |
dc.contributor.author | van Loo, Inge Hm | - |
dc.contributor.author | Ackens, Robin | - |
dc.contributor.author | Posthouwer, Dirk | - |
dc.contributor.author | Koek, Ger H. | - |
dc.date.accessioned | 2022-09-15T07:29:50Z | - |
dc.date.available | 2022-09-15T07:29:50Z | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2022-08-25T09:09:40Z | - |
dc.identifier.citation | Journal of Virus Eradication, 8 (2) | - |
dc.identifier.uri | http://hdl.handle.net/1942/38086 | - |
dc.description.abstract | Background & aims: There are approximately 49,000 people (0.34%) in the Netherlands with a chronic hepatitis B virus (HBV) infection. It is unclear how many are linked to care and under follow-up in hepatitis outpatient clinics. This study determined the cascade of care and identified predictors for not being linked to care and loss to follow-up in Maastricht, the Netherlands. Methods: All hepatitis B surface antigen (HBsAg)-positive patients between December 1, 1996 and September 30, 2018 were retrospectively identified. Results: In total, 644 HBsAg-positive patients were identified; of whom 75 had acute HBV infection, 471 chronic HBV infection and 98 unknown. Out of 569 individuals with a chronic/unknown HBV status, 134/569 (23.6%) were not linked to care and 58.7% (195/332 after excluding those who died or achieved HBsAg-seroclearance) were loss to follow-up (LTFU). A predictor for not being linked to care was Caucasian ethnicity (odds ratio (OR) = 2.76 (95% Confidence Interval (CI) = 1.21-6.29); p =.015). Predictors for LTFU were older age (OR = 0.97 (CI = 0.94-0.99); p =.008), HBV DNA >20,000 IU/mL (OR = 0.44 (CI = 0.21 - 0.93); p =.033) and Asian ethnicity (OR = 0.46, (CI = 0.21-1.00); p =.050). Rates of not being linked to care and LTFU decreased over time from 12.7% in 1996 to 4.4% in 2018 and from 79.2% in 1996 to 37.2% in 2018, respectively. Conclusions: A considerable amount of HBsAg-positive individuals were not linked to care or LTFU. This study indicates that ethnicity plays a role in linkage to care and follow-up. Further research is needed to elaborate on those results. | - |
dc.description.sponsorship | This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors. | - |
dc.language.iso | en | - |
dc.publisher | MEDISCRIPT LTD | - |
dc.rights | 2022 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | - |
dc.subject.other | Hepatitis B | - |
dc.subject.other | Cascade of care | - |
dc.subject.other | Linkage to care | - |
dc.subject.other | Loss to follow-up | - |
dc.subject.other | Ethnicity The Netherlands | - |
dc.title | Cascade of care among hepatitis B patients in Maastricht, the Netherlands, 1996 to 2018 | - |
dc.type | Journal Contribution | - |
dc.identifier.issue | 2 | - |
dc.identifier.volume | 8 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | van Oorschot, E (corresponding author), Maastricht UMC, P Debyelaan 25, NL-6229 HX Maastricht, Netherlands. | - |
dc.description.notes | eva.van.oorschot@mumc.nl; o.kuc@mumc.nl; a.oudelashof@mumc.nl; | - |
dc.description.notes | ihm.van.loo@mumc.nl; r.sckens@mumc.nl; d.posthouwer@mumc.nl; | - |
dc.description.notes | gh.koek@mumc.nl | - |
local.publisher.place | 1 MOUNTVIEW CT, 310 FRIERN BARNET LN, LONDON, N20 0LD, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
dc.identifier.doi | 10.1016/j.jve.2022.100075 | - |
dc.identifier.pmid | 35784678 | - |
dc.identifier.isi | 000836448600005 | - |
dc.contributor.orcid | van Oorschot, Eva/0000-0001-5291-4320 | - |
local.provider.type | wosris | - |
local.description.affiliation | [van Oorschot, Eva] Maastricht Univ, Fac Hlth Med & Life Sci, Maastricht, Netherlands. | - |
local.description.affiliation | [van Oorschot, Eva] Maastricht Univ Med Ctr, Dept Internal Med, Div Gastroenterol & Hepatol, Maastricht, Netherlands. | - |
local.description.affiliation | [Koc, Ozgur M.; Lashof, Astrid Ml Oude; van Loo, Inge Hm; Posthouwer, Dirk] Maastricht Univ Med Ctr, Sch Nutr & Translat Res Metab NUTRIM, Dept Med Microbiol, Maastricht, Netherlands. | - |
local.description.affiliation | [Koc, Ozgur M.] Ziekenhuis Oost Limburg, Dept Gastroenterol & Hepatol, Genk, Belgium. | - |
local.description.affiliation | [Koc, Ozgur M.] Hasselt Univ, Fac Med & Life Sci, Hasselt, Belgium. | - |
local.description.affiliation | [Lashof, Astrid Ml Oude; Posthouwer, Dirk] Maastricht Univ Med Ctr, Dept Internal Med, Div Infect Dis, Maastricht, Netherlands. | - |
local.description.affiliation | [van Loo, Inge Hm] Maastricht Univ, Care & Publ Hlth Res Inst CAPHRI, Maastricht, Netherlands. | - |
local.description.affiliation | [Ackens, Robin] Maastricht Univ Med Ctr, Dept Integrated Care, Maastricht, Netherlands. | - |
local.description.affiliation | [Koek, Ger H.] Maastricht Univ, Sch Nutr & Translat Res Metab Nutrim, Maastricht, Netherlands. | - |
local.description.affiliation | [Koek, Ger H.] Rhein Westfal TH Aachen, Dept Visceral & Transplantat Surg, Klinikum, Aachen, Germany. | - |
local.description.affiliation | [Koek, Ger H.] Maastricht Univ, Dept Internal Med, Div Gastroenterol & Hepatol, Maastricht, Netherlands. | - |
local.uhasselt.international | yes | - |
item.validation | ecoom 2023 | - |
item.fulltext | With Fulltext | - |
item.fullcitation | van Oorschot, Eva; KOC, Ozgur; Lashof, Astrid Ml Oude; van Loo, Inge Hm; Ackens, Robin; Posthouwer, Dirk & Koek, Ger H. (2022) Cascade of care among hepatitis B patients in Maastricht, the Netherlands, 1996 to 2018. In: Journal of Virus Eradication, 8 (2). | - |
item.accessRights | Open Access | - |
item.contributor | van Oorschot, Eva | - |
item.contributor | KOC, Ozgur | - |
item.contributor | Lashof, Astrid Ml Oude | - |
item.contributor | van Loo, Inge Hm | - |
item.contributor | Ackens, Robin | - |
item.contributor | Posthouwer, Dirk | - |
item.contributor | Koek, Ger H. | - |
crisitem.journal.issn | 2055-6640 | - |
crisitem.journal.eissn | 2055-6659 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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Cascade of care among hepatitis B patients in Maastricht, the Netherlands, 1996 to 2018.pdf | Published version | 2.06 MB | Adobe PDF | View/Open |
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