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http://hdl.handle.net/1942/38128
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DC Field | Value | Language |
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dc.contributor.author | Bedenic, Branka | - |
dc.contributor.author | Likic, Sasa | - |
dc.contributor.author | Zizek, Marta | - |
dc.contributor.author | Bratic, Vesna | - |
dc.contributor.author | D'ONOFRIO, Valentino | - |
dc.contributor.author | Cavric, Gordana | - |
dc.contributor.author | Pavlisa, Gordana | - |
dc.contributor.author | Vodanovic, Marijo | - |
dc.contributor.author | GYSSENS, Inge | - |
dc.contributor.author | Barisic, Ivan | - |
dc.date.accessioned | 2022-09-21T08:13:58Z | - |
dc.date.available | 2022-09-21T08:13:58Z | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2022-09-07T13:34:28Z | - |
dc.identifier.citation | JOURNAL OF CHEMOTHERAPY, 35 (4) , p. 281-291 | - |
dc.identifier.uri | http://hdl.handle.net/1942/38128 | - |
dc.description.abstract | Blood samples were collected alongside with routine blood cultures (BC) from patients with suspected sepsis, to evaluate the prevalence of different causative agents in patients with bacteraemia. Among 667 blood samples, there were 122 positive BC (18%). Haemoglobin content, platelet number, and systolic blood pressure values were significantly lower in patients with positive BC, whereas serum lactate levels, CRP, creatinine and urea content were significantly higher in patients with positive BC. The rate of multidrug (MDR) or extensively drug resistant (XDR) bacteria was 24% (n = 29): Klebsiella pneumoniae (9), Pseudomonas aeruginosa (9), Acinetobacter baumannii (4), Escherichia coli (1), vancomycin resistant Enterococcus spp (VRE) (3), and methicillin-resistant Staphylococcus aureus MRSA (3). The dominant resistance mechanisms were the production of extended-spectrum beta-lactamases, OXA-48 carbapenemase, and colistin resistance in K. pneumoniae, VIM metallo-beta-lactamases in P. aeruginosa and OXA-23-like oxacillinases in A. baumannii. The study revealed high rate of MDR strains among positive BCs in Zagreb, Croatia. | - |
dc.description.sponsorship | The study was funded by project FAPIC (Fast assay for pathogen identification and characterization, Horizon 2020 programme, number: 634137). | - |
dc.language.iso | en | - |
dc.publisher | TAYLOR & FRANCIS LTD | - |
dc.subject.other | Multidrug-resistant bacteria | - |
dc.subject.other | Klebsiella pneumonia | - |
dc.subject.other | eAcinetobacter baumannii | - |
dc.subject.other | bloodstream infections | - |
dc.subject.other | extended-spectrum beta-lactamases | - |
dc.title | Causative agents of bloodstream infections in two Croatian hospitals and their resistance mechanisms | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 291 | - |
dc.identifier.issue | 4 | - |
dc.identifier.spage | 281 | - |
dc.identifier.volume | 35 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Bedenic, B (corresponding author), Univ Zagreb, Univ Hosp Ctr Zagreb, Sch Med, Clin Dept Clin & Mol Microbiol, Zagreb, Croatia. | - |
dc.description.notes | branka.bedenic@kbc-zagreb.hr | - |
local.publisher.place | 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND | - |
local.type.refereed | Refereed | - |
local.type.specified | Article | - |
local.type.programme | H2020 | - |
local.relation.h2020 | 634137 | - |
dc.identifier.doi | 10.1080/1120009X.2022.2104294 | - |
dc.identifier.pmid | 35975598 | - |
dc.identifier.isi | 000842550500001 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Bedenic, Branka; Likic, Sasa; Pavlisa, Gordana] Univ Zagreb, Sch Med, Zagreb, Croatia. | - |
local.description.affiliation | [Bedenic, Branka] Univ Hosp Ctr Zagreb, Zagreb, Croatia. | - |
local.description.affiliation | [Zizek, Marta] Univ Zagreb, Fac Sci, Zagreb, Croatia. | - |
local.description.affiliation | [Bratic, Vesna; D'Onofrio, Valentino; Gyssens, Inge] Hasselt Univ, Fac Med & Life Sci, Hasselt, Belgium. | - |
local.description.affiliation | [Bratic, Vesna; D'Onofrio, Valentino] Jessa Hosp, Dept Infect Dis & Immun, Hasselt, Belgium. | - |
local.description.affiliation | [Bratic, Vesna; D'Onofrio, Valentino] Radboud Univ Nijmegen, Med Ctr, Nijmegen, Netherlands. | - |
local.description.affiliation | [Cavric, Gordana; Gyssens, Inge] Univ Hosp Merkur, Dept Internal Med, Zagreb, Croatia. | - |
local.description.affiliation | [Cavric, Gordana; Gyssens, Inge] Univ Hosp Merkur, Intens Care Unit, Zagreb, Croatia. | - |
local.description.affiliation | [Pavlisa, Gordana] Univ Hosp Ctr Zagreb, Clin Pulm Dis, Zagreb, Croatia. | - |
local.description.affiliation | [Vodanovic, Marijo] Univ Hosp Ctr Zagreb, Dept Internal Med, Div Hematol, Zagreb, Croatia. | - |
local.description.affiliation | [Vodanovic, Marijo] Univ Appl Hlth Sci, Zagreb, Croatia. | - |
local.description.affiliation | [Barisic, Ivan] Austrian Inst Technol, Vienna, Austria. | - |
local.uhasselt.international | yes | - |
item.fulltext | With Fulltext | - |
item.fullcitation | Bedenic, Branka; Likic, Sasa; Zizek, Marta; Bratic, Vesna; D'ONOFRIO, Valentino; Cavric, Gordana; Pavlisa, Gordana; Vodanovic, Marijo; GYSSENS, Inge & Barisic, Ivan (2022) Causative agents of bloodstream infections in two Croatian hospitals and their resistance mechanisms. In: JOURNAL OF CHEMOTHERAPY, 35 (4) , p. 281-291. | - |
item.accessRights | Restricted Access | - |
item.contributor | Bedenic, Branka | - |
item.contributor | Likic, Sasa | - |
item.contributor | Zizek, Marta | - |
item.contributor | Bratic, Vesna | - |
item.contributor | D'ONOFRIO, Valentino | - |
item.contributor | Cavric, Gordana | - |
item.contributor | Pavlisa, Gordana | - |
item.contributor | Vodanovic, Marijo | - |
item.contributor | GYSSENS, Inge | - |
item.contributor | Barisic, Ivan | - |
item.validation | ecoom 2023 | - |
crisitem.journal.issn | 1120-009X | - |
crisitem.journal.eissn | 1973-9478 | - |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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Causative agents of bloodstream infections in two Croatian hospitals and their resistance mechanisms.pdf Restricted Access | Early view | 1.17 MB | Adobe PDF | View/Open Request a copy |
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