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http://hdl.handle.net/1942/38804
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DC Field | Value | Language |
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dc.contributor.author | Churchill, Timothy W. | - |
dc.contributor.author | Yucel, Evin | - |
dc.contributor.author | DEFERM, Sebastien | - |
dc.contributor.author | Levine, Robert A. | - |
dc.contributor.author | Hung, Judy | - |
dc.contributor.author | BERTRAND, Philippe | - |
dc.date.accessioned | 2022-10-24T10:56:38Z | - |
dc.date.available | 2022-10-24T10:56:38Z | - |
dc.date.issued | 2022 | - |
dc.date.submitted | 2022-10-20T12:52:21Z | - |
dc.identifier.citation | JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 80 (7) , p. 739 -751 | - |
dc.identifier.issn | 0735-1097 | - |
dc.identifier.uri | http://hdl.handle.net/1942/38804 | - |
dc.description.abstract | Mitral annular calcification (MAC) is a common clinical finding and is associated with adverse clinical outcomes, but the clinical impact of MAC-related mitral valve (MV) dysfunction remains underappreciated. Patients with MAC frequently have stenotic, regurgitant, or mixed valvular disease, and this valvular dysfunction is increasingly recognized to be independently associated with worse prognosis. MAC-related MV dysfunction is a distinct pathophysiologic entity, and importantly much of the diagnostic and therapeutic paradigm from published rheumatic MV disease research cannot be applied in this context, leaving important gaps in our knowledge. This review summarizes the current epidemiology, pathophysiology, diagnosis, and classification of MAC-related MV dysfunction and proposes both an integrative definition and an overarching approach to this important and increasingly recognized clinical condition. (J Am Coll Cardiol 2022;80:739-751) (C) 2022 by the American College of Cardiology Foundation. | - |
dc.description.sponsorship | This study was supported in part by a grant from the Ellison Foundation and by National Institutes of Health grant R01 HL141917 (Drs Levine and Hung). The authors have reported that they have no relationships relevant to the contents of this paper to disclose. | - |
dc.language.iso | en | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.subject.other | MAC-related mitral valve dysfunction | - |
dc.subject.other | mitral annular calcification | - |
dc.subject.other | mitral regurgitation | - |
dc.subject.other | mitral stenosis | - |
dc.subject.other | transcatheter mitral valve replacement | - |
dc.title | Mitral Valve Dysfunction in Patients With Annular Calcification | - |
dc.type | Journal Contribution | - |
dc.identifier.epage | 751 | - |
dc.identifier.issue | 7 | - |
dc.identifier.spage | 739 | - |
dc.identifier.volume | 80 | - |
local.format.pages | 13 | - |
local.bibliographicCitation.jcat | A1 | - |
dc.description.notes | Bertrand, PB (corresponding author), Ziekenhuis Oost Limburg, Schiepse Bos 6, Genk, Belgium. | - |
dc.description.notes | philippe.bertrand@zol.be | - |
local.publisher.place | STE 800, 230 PARK AVE, NEW YORK, NY 10169 USA | - |
local.type.refereed | Refereed | - |
local.type.specified | Review | - |
dc.identifier.doi | 10.1016/j.jacc.2022.05.032 | - |
dc.identifier.pmid | 35953139 | - |
dc.identifier.isi | 000863527100007 | - |
dc.identifier.eissn | 1558-3597 | - |
local.provider.type | wosris | - |
local.description.affiliation | [Churchill, Timothy W.; Yucel, Evin; Levine, Robert A.; Hung, Judy; Bertrand, Philippe B.] Harvard Med Sch, Massachusetts Gen Hosp, Boston, MA 02115 USA. | - |
local.description.affiliation | [Deferm, Sebastien; Bertrand, Philippe B.] Ziekenhuis Oost Limburg, Dept Cardiol, Genk, Belgium. | - |
local.description.affiliation | [Deferm, Sebastien; Bertrand, Philippe B.] Hasselt Univ, Fac Med & Life Sci, Hasselt, Belgium. | - |
local.uhasselt.international | yes | - |
item.fullcitation | Churchill, Timothy W.; Yucel, Evin; DEFERM, Sebastien; Levine, Robert A.; Hung, Judy & BERTRAND, Philippe (2022) Mitral Valve Dysfunction in Patients With Annular Calcification. In: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 80 (7) , p. 739 -751. | - |
item.contributor | Churchill, Timothy W. | - |
item.contributor | Yucel, Evin | - |
item.contributor | DEFERM, Sebastien | - |
item.contributor | Levine, Robert A. | - |
item.contributor | Hung, Judy | - |
item.contributor | BERTRAND, Philippe | - |
item.validation | ecoom 2023 | - |
item.accessRights | Open Access | - |
item.fulltext | With Fulltext | - |
crisitem.journal.issn | 0735-1097 | - |
crisitem.journal.eissn | 1558-3597 | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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Mitral Valve Dysfunction in Patients With Annular Calcification.pdf | Published version | 3.27 MB | Adobe PDF | View/Open |
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