Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/38888
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dc.contributor.authorVANDORMAEL, Patrick-
dc.contributor.authorPUES, Astrid-
dc.contributor.authorSLEURS, Ellen-
dc.contributor.authorLIESENBORGS, Jori-
dc.contributor.authorVerschueren, P.-
dc.contributor.authorSOMERS, Veerle-
dc.date.accessioned2022-11-21T08:05:08Z-
dc.date.available2022-11-21T08:05:08Z-
dc.date.issued2022-
dc.date.submitted2022-11-03T17:33:39Z-
dc.identifier.citationANNALS OF THE RHEUMATIC DISEASES, 81 , p. 299-
dc.identifier.urihttp://hdl.handle.net/1942/38888-
dc.description.abstractScientific Abstracts 299 ANOSIM). Detailly, at the genera level, IIM patients had a higher abundance of Ente-rococcus, Veillonella, Streptococcus, et al. and a lower abundance of Roseburia, Lachnospira, Klebsiella, et al(Figure 1D, p < 0.05). In IIM patients, Fusobacteriota correlated positively with the ratio of Th1 cells (Figure 1E, p < 0.01), and there was a significant positive correlation between Synergistota and B lymphocyte (Figure 1E, p < 0.01). Besides, Euryarchaeota and Cyanobacteria were both positively and significantly related to IL-6, IFN-γ and C-reactive protein (CRP) (Figure 1E, p < 0.001). Conclusion: Richness and diversity of intestinal flora in IIM patients were impaired, which might participate in the pathogenesis of IIM by disturbing lym-phocyte subpopulations and cytokines. Regulating intestinal flora and restoring homeostasis might become a critical therapeutic methods of IIM. REFERENCES: [1] Xu Y, Sun J, Wan K, et al. Multiparametric cardiovascular magnetic resonance characteristics and dynamic changes in myocardial and skeletal muscles in idiopathic inflammatory cardiomyopathy. J Cardiovasc Magn Reson 2020;22(1):22.-
dc.description.sponsorshipPatrick Vandormael: None declared, Astrid Pues: None declared, Ellen Sleurs: None declared, Jori Liesenborgs: None declared, Patrick Verschueren Speakers bureau: Eli Lilly, MSD, Galapagos, Roularta, Consultant of: Galapagos, Gilead, Pfizer, Sidekick Health, Eli Lilly, Nordic Pharma, ABBVIE, Celltrion, BMS, UCB, Grant/research support from: Holder of the Pfizer Chair Management of Early Rheumatoid Arthritis at KU Leuven, Veerle Somers Grant/ research support from: research grant from Pfizer.-
dc.language.isoen-
dc.publisherBMJ PUBLISHING GROUP-
dc.titleNOVEL ANTIBODY BIOMARKERS THAT PREDICT FAILURE TO ACHIEVE EARLY AND SUSTAINED DISEASE REMISSION OR LOW DISEASE ACTIVITY AFTER INTENSIVE FIRST-LINE THERAPY IN RHEUMATOID ARTHRITIS-
dc.typeJournal Contribution-
dc.identifier.spage299-
dc.identifier.volume81-
local.format.pages1-
local.bibliographicCitation.jcatM-
local.publisher.placeBRITISH MED ASSOC HOUSE, TAVISTOCK SQUARE, LONDON WC1H 9JR, ENGLAND-
local.type.refereedRefereed-
local.type.specifiedMeeting Abstract-
dc.identifier.doi10.1136/annrheumdis-2022-eular.2388-
dc.identifier.isi000850279001084-
local.provider.typewosris-
local.description.affiliation[Vandormael, P.; Pues, A.; Sleurs, E.; Somers, V.] Hasselt Univ, Biomed Res Inst, Immunol & Infect, Diepenbeek, Belgium.-
local.description.affiliation[Liesenborgs, J.] Hasselt Univ, Expertise Ctr Digital Media, Computat Sci, Diepenbeek, Belgium.-
local.description.affiliation[Verschueren, P.] Univ Hosp Leuven, KULeuven, Rheumatol, Leuven, Belgium.-
local.uhasselt.internationalno-
item.fulltextWith Fulltext-
item.accessRightsRestricted Access-
item.fullcitationVANDORMAEL, Patrick; PUES, Astrid; SLEURS, Ellen; LIESENBORGS, Jori; Verschueren, P. & SOMERS, Veerle (2022) NOVEL ANTIBODY BIOMARKERS THAT PREDICT FAILURE TO ACHIEVE EARLY AND SUSTAINED DISEASE REMISSION OR LOW DISEASE ACTIVITY AFTER INTENSIVE FIRST-LINE THERAPY IN RHEUMATOID ARTHRITIS. In: ANNALS OF THE RHEUMATIC DISEASES, 81 , p. 299.-
item.contributorVANDORMAEL, Patrick-
item.contributorPUES, Astrid-
item.contributorSLEURS, Ellen-
item.contributorLIESENBORGS, Jori-
item.contributorVerschueren, P.-
item.contributorSOMERS, Veerle-
crisitem.journal.issn0003-4967-
crisitem.journal.eissn1468-2060-
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