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Title: | Clinical Validation of a New Enhanced Stent Imaging Method | Authors: | Ghafari, Chadi Houissa, Khalil DENS, Jo Ungureanu, Claudiu Kayaert, Peter Constant, Cyril Carlier, Stephane |
Issue Date: | 2023 | Publisher: | MDPI | Source: | Algorithms, 16 (6) (Art N° 276) | Abstract: | (1) Background: Stent underexpansion is the main cause of stent thrombosis and restenosis. Coronary angiography has limitations in the assessment of stent expansion. Enhanced stent imaging (ESI) methods allow a detailed visualization of stent deployment. We qualitatively compare image results from two ESI system vendors (StentBoost & TRADE; (SB) and CAAS StentEnhancer & TRADE; (SE)) and report quantitative results of deployed stents diameters by quantitative coronary angiography (QCA) and by SE. (2) Methods: The ESI systems from SB and SE were compared and graded by two blinded observers for different characteristics: 1 visualization of the proximal and distal edges of the stents; 2 visualization of the stent struts; 3 presence of underexpansion and 4 calcifications. Stent diameters were quantitatively measured using dedicated QCA and SE software and compared to chart diameters according to the pressure of implantation. (3) Results: A total of 249 ESI sequences were qualitatively compared. Inter-observer variability was noted for strut visibility and total scores. Inter-observer agreement was found for the assessment of proximal stent edge and stent underexpansion. The predicted chart diameters were 0.31 & PLUSMN; 0.30 mm larger than SE diameters (p < 0.05). Stent diameters by SE after post-dilatation were 0.47 & PLUSMN; 0.31 mm smaller than the post-dilation balloon diameter (p < 0.05). SE-derived diameters significantly differed from QCA; by Bland-Altman analysis the bias was -0.37 & PLUSMN; 0.42 mm (p < 0.001). (4) Conclusions: SE provides an enhanced visualization and allows precise quantitative assessment of stent expansion without the limitations of QCA when overlapping coronary side branches are present. | Notes: | Carlier, S (corresponding author), Univ Mons UMONS, Dept Cardiol, B-7000 Mons, Belgium.; Carlier, S (corresponding author), CHU Ambroise Pare, Cardiol Dept, B-7000 Mons, Belgium. chadi.ghafari@umons.ac.be; khalilhouissa@gmail.com; jo.dens@zol.be; claudiu-mih.ungureanu@jolimont.be; peter.kayaert@jessazh.be; cyril.constant@ulb.ac.be; stephane.carlier@umons.ac.be |
Keywords: | stent;percutaneous coronary intervention;quantitative coronary angiography | Document URI: | http://hdl.handle.net/1942/40560 | e-ISSN: | 1999-4893 | DOI: | 10.3390/a16060276 | ISI #: | 001013888200001 | Rights: | 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/). | Category: | A1 | Type: | Journal Contribution |
Appears in Collections: | Research publications |
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Clinical Validation of a New Enhanced Stent Imaging Method.pdf | Published version | 2.02 MB | Adobe PDF | View/Open |
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