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Title: | Model-based disease mapping using primary care registry data | Authors: | JANSSENS, Arne Vaes, Bert Van Pottelbergh, Gijs LIBIN, Pieter NEYENS, Thomas |
Issue Date: | 2024 | Publisher: | ELSEVIER SCI LTD | Source: | Spatial and spatio-temporal epidemiology (Print), 49 (Art N° 100654) | Abstract: | Background: Spatial modeling of disease risk using primary care registry data is promising for public health surveillance. However, it remains unclear to which extent challenges such as spatially disproportionate sampling and practice-specific reporting variation affect statistical inference. Methods: Using lower respiratory tract infection data from the INTEGO registry, modeled with a logistic model incorporating patient characteristics, a spatially structured random effect at municipality level, and an unstructured random effect at practice level, we conducted a case and simulation study to assess the impact of these challenges on spatial trend estimation. Results: Even with spatial imbalance and practice-specific reporting variation, the model performed well. Performance improved with increasing spatial sample balance and decreasing practice-specific variation. Conclusion: Our findings indicate that, with correction for reporting efforts, primary care registries are valuable for spatial trend estimation. The diversity of patient locations within practice populations plays an important role. | Notes: | Janssens, A (corresponding author), Kapucijnenvoer 7 Blok H,Bus 7001, B-3000 Leuven, Belgium. arne.janssens@kuleuven.be; bert.vaes@kuleuven.be; gijs.vanpottelbergh@kuleuven.be; pieter.libin@vub.be; thomas.neyens@uhasselt.be |
Keywords: | Primary care registry data;Spatial epidemiology;Bayesian spatial modeling;Lower respiratory tract infections;Passive sentinel surveillance;Simulation study | Document URI: | http://hdl.handle.net/1942/43322 | ISSN: | 1877-5845 | e-ISSN: | 1877-5853 | DOI: | 10.1016/j.sste.2024.100654 | ISI #: | 001242912800001 | Rights: | 2024 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/bync/4.0/) | Category: | A1 | Type: | Journal Contribution |
Appears in Collections: | Research publications |
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Model-based disease mapping using primary care registry data.pdf | Published version | 11.71 MB | Adobe PDF | View/Open |
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