Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/47462
Title: Personalizing transcranial electrical stimulation
Authors: VAN HOORNWEDER, Sybren 
Stagg, Charlotte J.
Wischnewski, Miles
Issue Date: 2025
Publisher: CELL PRESS
Source: Trends in neurosciences, 48 (9) , p. 663 -678
Abstract: Transcranial electrical stimulation (tES) encompasses non-invasive neuromodulation techniques, such as transcranial direct and alternating current stimulation, which modulate the central nervous system to probe causal links between the brain and behavior and treat disorders. Unfortunately, fixed stimulation paradigms induce variable effects due to intra-and interindividual factors. Consequently, personalized approaches to tES are increasingly used. In this review, we highlight this emerging domain of human brain stimulation, examining strategies for the personalization of stimulation parameters and their underlying rationales. Multiparameter personalization and the identification of markers indicating tES efficacy represent promising directions. Personalization is not a panacea for all the challenges of tES, but marks an essential step toward reducing the variability of this technique.
Notes: Van Hoornweder, S (corresponding author), Univ Hasselt, Fac Rehabil Sci, REVAL Rehabil Res Ctr, B-3590 Diepenbeek, Belgium.
sybren.vanhoornweder@uhasselt.be
Keywords: dosing strategies;individual variability;non-invasive brain stimulation;precision neuromodulation;transcranial alternating current stimulation (tACS);transcranial direct current stimulation (tDCS);Humans;Transcranial Direct Current Stimulation;Brain;Precision Medicine
Document URI: http://hdl.handle.net/1942/47462
ISSN: 0166-2236
e-ISSN: 1878-108X
DOI: 10.1016/j.tins.2025.07.007
ISI #: 001568986300001
Rights: 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies. Open access
Category: A1
Type: Journal Contribution
Appears in Collections:Research publications

Files in This Item:
File Description SizeFormat 
Personalizing transcranial electrical stimulation.pdfPublished version1.25 MBAdobe PDFView/Open
Show full item record

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.