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http://hdl.handle.net/1942/8363
Title: | Performance of gene selection and classification methods in a microarray setting: A simulation study | Authors: | VAN SANDEN, Suzy LIN, Dan BURZYKOWSKI, Tomasz |
Issue Date: | 2008 | Publisher: | TAYLOR & FRANCIS INC | Source: | COMMUNICATIONS IN STATISTICS-SIMULATION AND COMPUTATION, 37(2). p. 409-424 | Abstract: | In a previous article, we investigated the performance of several classification methods for cDNA-microarrays. Via simulations, various experimental settings could be explored without having to conduct expensive microarray studies. For the selection of genes, on which classification was based, one particular method was applied. Gene selection is, however, a very important aspect of classification. We extend the previous study by considering several gene selection methods. Furthermore, the stability of the methods with respect to distributional assumptions is examined by also considering data simulated from a symmetric and asymmetric Laplace distribution, in addition to normally distributed microarray data. | Notes: | Hasselt Univ, Ctr Stat, B-3590 Diepenbeek, Belgium. | Keywords: | cDNA microarray; class prediction; gene selection; simulation study | Document URI: | http://hdl.handle.net/1942/8363 | ISSN: | 0361-0918 | e-ISSN: | 1532-4141 | ISI #: | 000256386400014 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2009 |
Appears in Collections: | Research publications |
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File | Description | Size | Format | |
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PERFORMANCE OF GENE SELECTION AND CLASSIFICATION METHODS.pdf | Peer-reviewed author version | 327.24 kB | Adobe PDF | View/Open |
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