|
| | Issue Date | Title | Contributor(s) | Type | Cat. |
| 1 | 2024 | Novel insights in phosphodiesterase 4 subtype inhibition to target neuroinflammation and stimulate remyelination | SCHEPERS, Melissa; VANMIERLO, Tim | Journal Contribution | A2 |
| 2 | 2024 | The sphingosine-1-phosphate receptor 1 modulator ponesimod repairs cuprizone-induced demyelination and induces oligodendrocyte differentiation | WILLEMS, Emily; SCHEPERS, Melissa; PICCART, Elisabeth; WOLFS, Esther; HELLINGS, Niels; Ait-Tihyaty, Maria; VANMIERLO, Tim | Journal Contribution | A1 |
| 3 | 2024 | Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays | VAN VEGGEL, Lieve; Mocking, Tamara A. M.; Sijben, Hubert J.; Liu, Rongfang; Gonzalez, Marina Gorostiola; Dilweg, Majlen A.; Royakkers, Jeroen; Li, Anna; Kumar, Vijay; Dong, Yin Yao; Bullock, Alex; Sauer, David B.; Dilien , Hanne; van Westen, Gerard J. P.; Schreiber, Rudy; Heitman, Laura H.; VANMIERLO, Tim | Journal Contribution | A1 |
| 4 | 2024 | The Impact of Sample Storage on Blood Methylation: Towards Assessing Myelin Gene Methylation as a Biomarker for Progressive Multiple Sclerosis | TIANE, Assia; SOMERS, Veerle; HELLINGS, Niels; van den Hove, DLA; VANMIERLO, Tim | Journal Contribution | A1 |
| 5 | 2023 | Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury | Mussen, Femke; VAN BROECKHOVEN, Jana; HELLINGS, Niels; SCHEPERS, Melissa; VANMIERLO, Tim | Journal Contribution | A1 |
| 6 | 2023 | Phosphodiesterase (PDE) 4 inhibition boosts Schwann cell myelination in a 3D regeneration model | SCHEPERS, Melissa; Malheiro, Afonso; Gamardo, Adrian Seijas; HELLINGS, Niels; Prickaerts, Jos; Moroni, Lorenzo; VANMIERLO, Tim; Wieringa, Paul | Journal Contribution | A1 |
| 7 | 2023 | Identification of Side Chain Oxidized Sterols as Novel Liver X Receptor Agonists with Therapeutic Potential in the Treatment of Cardiovascular and Neurodegenerative Diseases | ZHAN, Na; Wang, Boyang; MARTENS, Nikita; Liu , Yankai; Zhao, Shangge; Voortman, Gardi; Van Rooij, Jeroen; Leijten, Frank; VANMIERLO, Tim; Kuipers, Folkert; Jonker, Johan W.; Bloks, Vincent W.; Luetjohann, Dieter; Palumbo, Marcella; Zimetti, Francesca; Adorni, Maria Pia; Liu, Hongbing; Mulder, Monique T. | Journal Contribution | A1 |
| 8 | 2023 | sGC modulators as cognitive enhancers: neuronal and/ or vascular? | Prickaerts, Jos; NELISSEN, Ellis; VANMIERLO, Tim; Sandner, Peter | Journal Contribution | M |
| 9 | 2023 | Brain-penetrant sGC stimulator BAY-747 and activator runcaciguat act as cognitive enhancers via differential neuroplastic mechanisms | NELISSEN, Ellis; VANMIERLO, Tim; Sandner, Peter; Prickaerts, Jos | Journal Contribution | M |
| 10 | 2023 | Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-beta pathology | PAES, Dean; SCHEPERS, Melissa; WILLEMS, Emily; ROMBAUT, Ben; TIANE, Assia; Solomina, Yevgeniya; Tibbo, Amy; Blair, Connor; Kyurkchieva, Elka; Baillie, George S.; Ricciarelli, Roberta; Brullo, Chiara; Fedele, Ernesto; Bruno, Olga; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos | Journal Contribution | A1 |
| 11 | 2023 | From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions | TIANE, Assia; SCHEPERS, Melissa; Reijnders, Rick A.; VAN VEGGEL, Lieve; CHENINE, Sarah; ROMBAUT, Ben; Dempster, Emma; Verfaillie, Catherine; Wasner, Kobi; Gruenewald, Anne; Prickaerts, Jos; Pishva, Ehsan; HELLINGS, Niels; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A1 |
| 12 | 2023 | Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment | Manukjan, Narek; Majcher, Daria; Leenders, Peter; Caiment, Florian; van Herwijnen, Marcel; Smeets, Hubert J. J.; Suidgeest, Ernst; van der Weerd, Louise; VANMIERLO, Tim; Jansen, Jacobus F. A.; Backes, Walter H. H.; van Oostenbrugge, Robert J. J.; Staals, Julie; Fulton, Daniel; Ahmed, Zubair; Blankesteijn, W. Matthijs; Foulquier, Sebastien | Journal Contribution | A1 |
| 13 | 2023 | Presynaptic Release-Regulating Sphingosine 1-Phosphate 1/3 Receptors in Cortical Glutamatergic Terminals: Adaptations in EAE Mice and Impact of Therapeutic FTY720 | Roggeri, Alessandra; Olivero, Guendalina; Usai, Cesare; VANMIERLO, Tim; Pittaluga, Anna | Journal Contribution | A1 |
| 14 | 2023 | Generation of a ST3GAL3 null mutant induced pluripotent stem cell (iPSC) line (UKWMPi002-A-3) by CRISPR/Cas9 genome editing | DIOUF, David; Vitale, Maria Rosaria; Zoeller, Johanna Eva Maria; Pineau, Ana -Magdalena; Klopocki, Eva; Hamann, Catharina; Ziegler, Georg Christoph; VANMIERLO, Tim; Van den Hove, Daniel; Lesch, Klaus-Peter | Journal Contribution | A1 |
| 15 | 2023 | Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment? | NELISSEN, Ellis; SCHEPERS, Melissa; PONSAERTS, Laura; Foulquier, Sebastien; BRONCKAERS, Annelies; VANMIERLO, Tim; Sandner, Peter; Prickaerts, Jos | Journal Contribution | A1 |
| 16 | 2023 | A perspective on causality assessment in epigenetic research on neurodegenerative disorders | KOULOUSAKIS, Philippos; TIANE, Assia; HELLINGS, Niels; Prickaerts, Jos; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A2 |
| 17 | 2023 | Exogenous Oxytocin Administration Restores Memory in Female APP/PS1 Mice | KOULOUSAKIS, Philippos; WILLEMS, Emily; SCHEPERS, Melissa; ROMBAUT, Ben; Prickaerts, Jos; VANMIERLO, Tim; van den Hove, Daniel | Journal Contribution | A1 |
| 18 | 2023 | Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis | SCHEPERS, Melissa; PAES, Dean; TIANE, Assia; ROMBAUT, Ben; PICCART, Elisabeth; VAN VEGGEL, Lieve; GERVOIS, Pascal; Brullo, Chiara; Bruno, Olga; Fedele, Ernesto; Ricciarelli, Roberta; Ffrench-Constant, Charles; Bechler, Marie E.; Schaik, Pauline van; WOLFS, Esther; LAMBRICHTS, Ivo; Baron, Wia; LEFEVERE, Evy; Wasner, Kobi; Gruenewald, Anne; Verfaillie, Catherine; Wieringa, Paul; Prickaerts, Jos; BROUX, Bieke; BAETEN, Paulien; HELLINGS, Niels; VANMIERLO, Tim | Journal Contribution | A1 |
| 19 | 2023 | Cerebral microvascular endothelial cell-derived extracellular vesicles regulate blood - brain barrier function | HOSSEINKHANI, Baharak; DURAN, Gayel; HOEKS, Cindy; HERMANS, Doryssa; SCHEPERS, Melissa; BAETEN, Paulien; POELMANS, Joren; Coenen, Britt; Bekar, Kuebra; Pintelon, Isabel; Timmermans , Jean-Pierre; VANMIERLO, Tim; MICHIELS, Luc; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | A1 |
| 20 | 2023 | Shortening arthrodesis combined with limited fasciectomy in severe recurrent Dupuytren's disease of the fifth finger | VANMIERLO, Bert; Van Eecke, Eduard; Decramer, Arne; VANMIERLO, Tim; Van Royen, Kjell; Goubau, Jean | Journal Contribution | A1 |
| 21 | 2023 | Therapeutic administration of mouse mast cell protease 6 improves functional recovery after traumatic spinal cord injury in mice by promoting remyelination and reducing glial scar formation | VANGANSEWINKEL, Tim; LEMMENS, Stefanie; TIANE, Assia; GEURTS, Nathalie; DOOLEY, Dearbhaile; VANMIERLO, Tim; Pejler, Gunnar; HENDRIX, Sven | Journal Contribution | A1 |
| 22 | 2023 | Activation of Liver X Receptors and Peroxisome Proliferator-Activated Receptors by Lipid Extracts of Brown Seaweeds: A Potential Application in Alzheimer's Disease? | MARTENS, Nikita; ZHAN, Na; Voortman, Gardi; Leijten, Frank P. J.; van Rheenen, Connor; van Leerdam, Suzanne; Geng, Xicheng; HUYBRECHTS, Michiel; Liu, Hongbing; Jonker, Johan W. W.; Kuipers, Folkert; Lutjohann, Dieter; VANMIERLO, Tim; Mulder, Monique T. T. | Journal Contribution | A1 |
| 23 | 2023 | Carnosine synthase deficiency aggravates neuroinflammation in multiple sclerosis | SPAAS, Jan; Van der Stede, Thibaux; de Jager, Sarah; VAN DE WATERWEG BERENDS, Annet; TIANE, Assia; Baelde, Hans; Baba, Shahid P.; Eckhardt, Matthias; WOLFS, Esther; VANMIERLO, Tim; HELLINGS, Niels; OP 'T EIJNDE, Bert; Derave, Wim | Journal Contribution | A1 |
| 24 | 2022 | Ponesimod, mono-selective sphingosine-1-phosphate receptor 1 modulator enhances oligodendrocyte precursor cell differentiation | WILLEMS, Emily; SCHEPERS, Melissa; Ait-Tihyaty, M.; VANMIERLO, Tim | Journal Contribution | M |
| 25 | 2022 | The monoselective sphingosine-1-phosphate receptor-1 modulator ponesimod enhances remyelination in the cuprizone model of demyelination | SCHEPERS, Melissa; WILLEMS, Emily; Ait-Tihyaty, M.; VANMIERLO, Tim | Journal Contribution | M |
| 26 | 2022 | BROWN SEAWEEDS ACTIVATING LIVER X RECEPTORS: POTENTIAL ROLE IN THE PREVENTION OF NEURODEGENERATIVE AND CARDIOMETABOLIC DISEASES | Mulder, M. T.; MARTENS, Nikita; Zhan , N.; Voortman-Minderman, G.; Liu, H.; Kuipers, F.; Jonker, H.; Luetjohann, D.; VANMIERLO, Tim | Journal Contribution | M |
| 27 | 2022 | LXR-beta signalling is a key mediator in the pathogenesis of aortic valve stenosis and its prevention by saringosterol | Noethel, M.; Schmidt, A.; Mulder, M. T.; VANMIERLO, Tim; Friedrichs, S.; Schmidt , S. V.; Voortman, G.; Goody, P.; Zimmer, S.; Nickenig, G.; Luetjohann, D.; Jehle, J. | Journal Contribution | M |
| 28 | 2022 | Computational investigation of the dynamic control of cAMP signaling by PDE4 isoform types | PAES, Dean; Hermans, Sammy; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos; Carlier, Aurelie | Journal Contribution | A1 |
| 29 | 2022 | The sGC stimulator BAY-747 and activator runcaciguat can enhance memory in vivo via differential hippocampal plasticity mechanisms | NELISSEN, Ellis; Possemis, Nina; Van Goethem, Nick P.; SCHEPERS, Melissa; Mulder-Jongen, Danielle A. J.; Dietz, Lisa; JANSSEN, Wiebke; Gerisch, Michael; Huser, Jorg; Sandner, Peter; VANMIERLO, Tim; Prickaerts, Jos | Journal Contribution | A1 |
| 30 | 2022 | THE USE OF SEAWEED-DERIVED PHYTOSTEROLS TO DEFEAT ALZHEIMER'S DISEASE | MARTENS, Nikita; SCHEPERS, Melissa; ZHAN, Na; Leijten, F.; Voortman-Minderman, G.; TIANE, Assia; ROMBAUT, Ben; Poisquet, Janne; Van de Sande, N.; Kerksiek, A.; Kuipers, F.; Jonker, J. W.; Liu, H.; Luetjohann, D.; VANMIERLO, Tim; Mulder, M. T. | Journal Contribution | M |
| 31 | 2022 | Editorial: Cyclic Nucleotide Phosphodiesterases (PDEs) in Immune Regulation and Inflammation | Brocke, Stefan; Epstein, Paul M.; Nelson, Robert; VANMIERLO, Tim | Journal Contribution | A2 |
| 32 | 2022 | The Selective Sphingosine-1-Phosphate Receptor 1 (S1P1) Modulator Ponesimod Enhances Murine Oligodendrocyte Precursor Cell (OPC) Differentiation and Retains OPC Migration | Ait-Tihyaty, M.; PICCART, Elisabeth; SCHEPERS, Melissa; WILLEMS, E; DiBernardo, A.; VANMIERLO, Tim | Journal Contribution | M |
| 33 | 2022 | INCREASING CAMP LEVELS BY INHIBITING PHOSPHODIESTERASE 4D IMPROVES NERVE CONDUCTION AND FUNCTIONAL RECOVERY IN A MOUSE MODEL FOR CHARCOT MARIE TOOT 1A | VANGANSEWINKEL, Tim; SCHEPERS, Melissa; LIBBERECHT, Karen; Jacobs , Darren; PICCART, Elisabeth; JEURISSEN, Hanne; Prior, Robert; Ricciarelli, Roberta; Bruno, Olga; Fedele, Ernesto; Brullo, Chiara; Prickaerts, Jos; Van Den Bosch , Ludo; VANMIERLO, Tim; LAMBRICHTS, Ivo; WOLFS, Esther | Journal Contribution | M |
| 34 | 2021 | DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation. | TIANE, Assia; SCHEPERS, Melissa; Riemens, R.; ROMBAUT, Ben; VANDORMAEL, Patrick; SOMERS, Veerle; Prickaerts, J.; HELLINGS, Niels; Van den Hove, D.; VANMIERLO, Tim | Journal Contribution | M |
| 35 | 2021 | Disrupted-In-Schizophrenia 1 controls microglial movement and phagocytosis | KESSELS, Sofie; BERDEN, Lisa; AGUIAR ALPIZAR, Yeranddy; BEEKEN, Jolien; TRIPPAERS, Chloe; ROMBAUT, Ben; Ishizuka, K; Nguyen, L; Antel, J; Healy, L; Cowley, S; DEWACHTER, Ilse; Rigo, J; VANMIERLO, Tim; Sawa, A; BRONE, Bert | Journal Contribution | M |
| 36 | 2021 | P.0261 Investigation of cdh13’s role in neurodevelopmental disorders using isogenic induced pluripotent stem cell (ipsc) lines and different cdh13 snp variants | Vitale, M. R.; Zoeller, J. E. M.; Ziegler, G. C.; Von den Hove, D.; VANMIERLO, Tim; Lesch, K. P. | Journal Contribution | M |
| 37 | 2021 | Neuroinflammation in Ischemic Stroke: Inhibition of cAMP-Specific Phosphodiesterases (PDEs) to the Rescue | PONSAERTS, Laura; ALDERS, Lotte; SCHEPERS, Melissa; de Oliveira, RMW; Prickaerts, J; VANMIERLO, Tim; BRONCKAERS, Annelies | Journal Contribution | A1 |
| 38 | 2021 | 24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer’s Disease | MARTENS, Nikita; SCHEPERS, Melissa; Zhan, Na; Leijten, Frank; Voortman, Gardi; TIANE, Assia; ROMBAUT, Ben; POISQUET, Janne; van de Sande, Nienke; Kerksiek, Anja; Kuipers, Folkert; Jonker, Johan W.; Liu, Hongbing; Lütjohann, Dieter; VANMIERLO, Tim; Mulder, Monique T. | Journal Contribution | A1 |
| 39 | 2021 | Positive effects of roflumilast on behavior, neuroinflammation, and white matter injury in mice with global cerebral ischemia | Vilhena, Emanuella R.; Bonato, Jessica M.; SCHEPERS, Melissa; Kunieda, Juliana K. C.; Milani, Humberto; VANMIERLO, Tim; Prickaerts, Jos; de Oliveira, Rubia M. W. | Journal Contribution | A1 |
| 40 | 2021 | Dietary advanced glycation endproducts (AGEs) increase their concentration in plasma and tissues, result in inflammation and modulate gut microbial composition in mice; evidence for reversibility | van Dongen, Katja C. W.; Linkens, Armand M. A.; WETZELS, Suzan; WOUTERS, Kristiaan; VANMIERLO, Tim; van de Waarenburg, Marjo P. H.; Scheijen, Jean L. J. M.; de Vos, Willem M.; Belzer, Clara; Schalkwijk, Casper G. | Journal Contribution | A1 |
| 41 | 2021 | The Molecular Biology of Phosphodiesterase 4 Enzymes as Pharmacological Targets: An Interplay of Isoforms, Conformational States, and Inhibitors | PAES, Dean; SCHEPERS, Melissa; ROMBAUT, Ben; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos; Michel, Martin | Journal Contribution | A1 |
| 42 | 2021 | DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation | TIANE, Assia; SCHEPERS, Melissa; Riemens, Renzo; ROMBAUT, Ben; VANDORMAEL, Patrick; SOMERS, Veerle; Prickaerts, Jos; HELLINGS, Niels; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A1 |
Loading...
5
0
5
0
false