Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/10119
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.advisor | RIGO, J. | - |
dc.contributor.author | SWINNEN, Nina | - |
dc.date.accessioned | 2009-12-14T09:34:06Z | - |
dc.date.available | 2009-12-14T09:34:06Z | - |
dc.date.issued | 2009 | - |
dc.identifier.uri | http://hdl.handle.net/1942/10119 | - |
dc.description.abstract | In this study the effect of glycine on 3 oligodendroglial cell lines was investigated. Patch-clamp results suggest that mainly Na+-dependent-like transporters are responsible for the glycine-induced inward current in the used cell lines. In the MO3.13 and OLN-93 cells there is also a small contribution of GlyT2s to the currents. When looking at the effect of glycine on cell proliferation, there is only an effect on the MO3.13 cells. Since the glycine-induced current in the MO3.13 cells is approximately six times larger than those induced in the HOG and OLN-93 cells, it is likely that the currents in the latter two are too small to trigger any downstream events. These results suggest that glycine can influence the proliferation of some, but not all, oligodendroglial cell lines. Verification of these results with primary cell cultures will give more information concerning the use of these cell lines as model for oligodendendrocyte progenitors. | - |
dc.format.mimetype | Application/pdf | - |
dc.language | nl | - |
dc.publisher | tUL Diepenbeek | - |
dc.title | Functional characterization of glycine effects on oligodendroglial cell lines | - |
dc.type | Theses and Dissertations | - |
local.format.pages | 43 | - |
local.bibliographicCitation.jcat | T2 | - |
dc.description.notes | 2de masterjaar in de biomedische wetenschappen - klinische moleculaire wetenschappen | - |
local.type.specified | Master thesis | - |
dc.bibliographicCitation.oldjcat | - | |
item.fullcitation | SWINNEN, Nina (2009) Functional characterization of glycine effects on oligodendroglial cell lines. | - |
item.fulltext | With Fulltext | - |
item.accessRights | Open Access | - |
item.contributor | SWINNEN, Nina | - |
Appears in Collections: | Master theses Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
04220642008249c.pdf | 1.86 MB | Adobe PDF | View/Open |
Page view(s)
52
checked on Sep 28, 2023
Download(s)
16
checked on Sep 28, 2023
Google ScholarTM
Check
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.