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Title: | Long-term effect of rehabilitation in coronary artery disease patients: randomized clinical trial of the impact of exercise volume | Authors: | HANSEN, Dominique DENDALE, Paul Raskin, Anita Schoonis, Annick BERGER, Jan Vlassak, Irmien Meeusen, Romain |
Issue Date: | 2010 | Publisher: | SAGE PUBLICATIONS LTD | Source: | CLINICAL REHABILITATION, 24 (4). p. 319-327 | Abstract: | Objective: To assess whether exercise volume during phase II rehabilitation affects long-term clinical benefits in patients with coronary artery disease. Design: Prospective randomized clinical trial with long-term follow-up. Setting: Hospital outpatient clinic. Subjects: Coronary artery disease patients (age 65 +/- 9 years, 82% males) attending a phase II rehabilitation programme were randomized into two groups of exercise volumes: 40-versus 60-minute training sessions. Patients exercised for three days per week for seven weeks, at 65% of baseline oxygen uptake capacity. Next, they were followed up for 18 months. Out of 165 patients with coronary artery disease who completed the exercise intervention, 119 attended the 18-month follow-up assessment. Main measurements: Body anthropometrics, resting haemodynamics, blood lipid profile, glycaemia, and C-reactive protein level, smoking behaviour, habitual physical activity, cardiovascular disease incidence and mortality. Results: In total population, a significant worsening of various cardiovascular disease risk factors was found at 18 months follow-up (P<0.05), and few patients (27% of total group) adhered to the recommended minimal physical activity level. No difference in change of body anthropometrics, resting haemodynamics, blood lipid profile, glycaemia, and C-reactive protein level, and smoking behaviour was seen between different exercise volumes (P>0.05). In addition, total cardiovascular disease incidence (13% versus 22% in 40-versus 60-minute group, respectively) and habitual physical activity were not different between groups (P>0.05). Conclusion: In patients with coronary artery disease following cardiac rehabilitation, the cardiovascular disease risk profile worsened significantly during long-term follow-up. A smaller exercise volume during phase II rehabilitation generated equal long-term clinical benefits compared to a greater exercise volume. | Notes: | [Meeusen, Romain] Vrije Univ Brussels, Fac LK, Dept Human Physiol & Sportsmed, B-1050 Brussels, Belgium. [Hansen, Dominique; Dendale, Paul; Raskin, Anita; Schoonis, Annick; Berger, Jan; Vlassak, Irmien] Jessa Hosp, Rehabil & Hlth Ctr, Heart Ctr Hasselt, Hasselt, Belgium. [Dendale, Paul] Hasselt Univ, Fac Med, Diepenbeek, Belgium. rmeeusen@vub.ac.be | Document URI: | http://hdl.handle.net/1942/10886 | ISSN: | 0269-2155 | e-ISSN: | 1477-0873 | DOI: | 10.1177/0269215509353262 | ISI #: | 000276174500004 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2011 |
Appears in Collections: | Research publications |
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