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http://hdl.handle.net/1942/12558
Title: | Optimalisatie en miniaturisatie van een NCD-gebaseerde immunosensor | Authors: | BEX, Geert Jan | Advisors: | WAGNER, Patrick HAENEN, Ken |
Issue Date: | 2010 | Publisher: | tUL Diepenbeek | Abstract: | C-reactief protein (CRP) is a significant marker for inflammatory diseases. Recent research also indicates that high CRP-concentrations in blood are a definite risk marker for cardiovascular diseases. Current standards for CRP-detection include turbidimetric and ELISA-assays. These methods are time-consuming, expensive and require educated medical personnel. An electronic antigen detection system could allow for a faster, simple and real-time determination. In this study an existing immunosensing platform will be optimalized and miniaturized. The immunosensor is based on nanocrystalline diamond (NCD), a very appealing material for biosensing purposes because of its interesting properties, namely biocompatibility, chemical inertia and the ability to change the electrical behavior through doping. A recent study proves that a NCD-based immunosensor could detect CRP with electrochemical impedance spectroscopy (EIS). This sensor will be miniaturized to a coplanar setup for future use in a | Notes: | master in de biomedische wetenschappen-bio-elektronica en nanotechnologie | Document URI: | http://hdl.handle.net/1942/12558 | Category: | T2 | Type: | Theses and Dissertations |
Appears in Collections: | Master theses |
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File | Description | Size | Format | |
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08269282009254.pdf | 2.09 MB | Adobe PDF | View/Open |
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