Please use this identifier to cite or link to this item: http://hdl.handle.net/1942/18046
Title: Validating cone-beam computed tomography for peri-implant bone morphometric analysis
Authors: HUANG, Yanru 
Van Dessel, Jeroen
Depypere, Maarten
EzEldeen, Mostafa
Iliescu, Alexandru Andrei
Dos Santos, Emanuela
LAMBRICHTS, Ivo 
LIANG, Xin 
Jacobs, Reinhilde
Issue Date: 2014
Publisher: NATURE PUBLISHING GROUP
Source: BONE RESEARCH, 2
Abstract: Cone-beam computed tomography (CBCT) has been recently used to analyse trabecular bone structure around dental implants. To validate the use of CBCT for three-dimensional (3D) peri-implant trabecular bone morphometry by comparing it to two-dimensional (2D) histology, 36 alveolar bone samples (with implants n=27 vs. without implants n=9) from six mongrel dogs, were scanned ex vivo using a high-resolution (80 mu m) CBCT. After scanning, all samples were decalcified and then sectioned into thin histological sections (similar to 6 mu m) to obtain high contrast 2D images. By using CT An imaging software, bone morphometric parameters including trabecular number (Tb.N), thickness (Tb.Th), separation (Tb.Sp) and bone volume fraction (BV/TV) were examined on both CBCT and corresponding histological images. Higher Tb. Th and Tb. Sp, lower BV/TV and Tb.N were found on CBCT images (P<0.001). Both measurements on the peri-implant trabecular bone structure showed moderate to high correlation (r=0.65-0.85). The Bland-Altman plots showed strongest agreement for Tb.Th followed by Tb.Sp, Tb.N and BV/TV, regardless of the presence of implants. The current findings support the assumption that peri-implant trabecular bone structures based on high-resolution CBCT measurements are representative for the underlying histological bone characteristics, indicating a potential clinical diagnostic use of CBCT-based peri-implant bone morphometric characterisation.
Notes: [Huang, Yan; Van Dessel, Jeroen; EzEldeen, Mostafa; Jacobs, Reinhilde] Univ Leuven, Fac Med, Dept Imaging & Pathol, OMFS IMPATH Res Grp, Leuven, Belgium. [Huang, Yan; Van Dessel, Jeroen; EzEldeen, Mostafa; Jacobs, Reinhilde] Univ Hosp Leuven, Leuven, Belgium. [Huang, Yan] Sichuan Univ, West China Hosp Stomatol, State Key Lab Oral Dis, Chengdu 610064, Peoples R China. [Depypere, Maarten] Katholieke Univ Leuven, ESAT PSI, Leuven, Belgium. [Iliescu, Alexandru Andrei] UMF Craiova, Fac Dent, Craiova, Romania. [Dos Santos, Emanuela] Pontificia Univ Catolica Parana, Sch Dent, Curitiba, Parana, Brazil. [Lambrichts, Ivo] Hasselt Univ, Biomed Res Inst, Diepenbeek, Belgium. [Liang, Xin] Dalian Med Univ, Sch Stomatol, Dalian, Peoples R China.
Document URI: http://hdl.handle.net/1942/18046
DOI: 10.1038/boneres.2014.10
ISI #: 000344998000001
Rights: © 2014 Sichuan University All rights reserved 2095-4700/14
Category: A1
Type: Journal Contribution
Validations: ecoom 2015
Appears in Collections:Research publications

Files in This Item:
File Description SizeFormat 
boneres201410.pdf1.4 MBAdobe PDFView/Open
Show full item record

SCOPUSTM   
Citations

17
checked on Sep 2, 2020

WEB OF SCIENCETM
Citations

20
checked on May 21, 2022

Page view(s)

44
checked on May 19, 2022

Download(s)

76
checked on May 19, 2022

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.