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Title: | Day-to-day reliability, agreement and discriminative validity of measuring walking-related performance fatigability in persons with Multiple Sclerosis | Authors: | VAN GEEL, Fanny VELDKAMP, Renee SEVERIJNS, Deborah Dalgas, Ulrik FEYS, Peter |
Issue Date: | 2020 | Publisher: | SAGE PUBLICATIONS LTD | Source: | Multiple Sclerosis Journal, 26 (13), pp. 1785-1789 | Abstract: | Background: Day-to-day reliability and cut-off values to detect abnormal walking fatigability (WF) remain to be investigated in persons with multiple sclerosis (pwMS). Methods: In all, 49 pwMS (mean Expanded Disability Status Scale (EDSS) ± standard deviation (SD): 3.3 ± 1.9) and 28 matched healthy controls (HC) performed the six-minute walking test (6MWT) on two different days to determine day-to-day reliability (intraclass correlation coefficient (ICC)) and limits of agreement (LOA) for five different equations of WF. Objective: To examine day-to-day reliability, agreement and discriminative validity for measuring WF. Results and conclusion: WF expressed as the ratio between the first and sixth minute had the best day-to-day reliability (ICC’s range of 0.76–0.95 and 0.60–0.86, respectively) in both pwMS and HC, while LOA were 15% and 7%, respectively. Ecological validity and clinical importance should be further investigated. | Keywords: | Reliability;fatigability;walking;assessment;multiple sclerosis | Document URI: | http://hdl.handle.net/1942/29781 | Link to publication/dataset: | https://journals.sagepub.com/eprint/U96PJGFRCVQTDXS7BDWC/full | ISSN: | 1352-4585 | e-ISSN: | 1477-0970 | DOI: | 10.1177/1352458519872465 | ISI #: | 000486891300001 | Rights: | The Author(s), 2019. Article reuse guidelines: sagepub.com/journalspermissions | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2020 |
Appears in Collections: | Research publications |
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