Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/33739
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Everaert, Celine | - |
dc.contributor.author | Volders, Pieter-Jan | - |
dc.contributor.author | Morlion, Annelien | - |
dc.contributor.author | THAS, Olivier | - |
dc.contributor.author | Mestdagh, Pieter | - |
dc.date.accessioned | 2021-03-28T12:25:21Z | - |
dc.date.available | 2021-03-28T12:25:21Z | - |
dc.date.issued | 2019 | - |
dc.date.submitted | 2021-03-28T12:24:08Z | - |
dc.identifier.uri | http://hdl.handle.net/1942/33739 | - |
dc.description.abstract | To understand biology and differences among various tissues or cell types, one typically searches for molecular features that display characteristic abundance patterns. Several specificity metrics have been introduced to identify tissue-specific molecular features, but these either require an equal number of replicates per tissue or they can't handle replicates at all. We describe a non-parametric specificity score that is compatible with unequal sample group sizes. To demonstrate its usefulness, the specificity score was calculated on all GTEx samples, detecting known and novel tissue-specific genes. A webtool was developed | - |
dc.language.iso | en | - |
dc.publisher | Cold Spring Harbor Laboratory | - |
dc.title | SPECS : a non-parameteric method to identify tissue-specific molecular features for unbalanced sample groups | - |
dc.type | Preprint | - |
local.format.pages | 5 | - |
local.bibliographicCitation.jcat | O | - |
local.type.refereed | Non-Refereed | - |
local.type.specified | Preprint | - |
dc.identifier.doi | 10.1101/656397 | - |
local.provider.type | bibtex | - |
local.uhasselt.uhpub | yes | - |
item.fullcitation | Everaert, Celine; Volders, Pieter-Jan; Morlion, Annelien; THAS, Olivier & Mestdagh, Pieter (2019) SPECS : a non-parameteric method to identify tissue-specific molecular features for unbalanced sample groups. | - |
item.fulltext | With Fulltext | - |
item.contributor | Everaert, Celine | - |
item.contributor | Volders, Pieter-Jan | - |
item.contributor | Morlion, Annelien | - |
item.contributor | THAS, Olivier | - |
item.contributor | Mestdagh, Pieter | - |
item.accessRights | Open Access | - |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
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656397v1.full.pdf | Non Peer-reviewed author version | 671.22 kB | Adobe PDF | View/Open |
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