Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/36239
Title: | Micelle Purification in Continuous Flow via Inline Dialysis | Authors: | VERSTRAETE, Kirsten BUCKINX, Axel ZAQUEN, Neomy JUNKERS, Tanja |
Issue Date: | 2021 | Publisher: | AMER CHEMICAL SOC | Source: | Macromolecules, 54 (8) , p. 3865 -3872 | Abstract: | Micelle dispersions purification is made available via inline flow dialysis in which micelles are separated from the organic solvent used to dissolve the block copolymers in the micelle formation step. Purification was performed using simple and cost-effective dialysis units employing cellulose membranes. The proposed setup allows us to remove THF from a micelle dispersion within a few hours almost entirely in a looped flow system, without significantly changing the micelle size. Purification is found to be independent of the exact flow rates and only on the circulation time through the dialysis units. The system is not only able to reduce the concentration of the organic solvent, but also water-soluble monomers can be removed. Further, the integration of the method into a full synthesis line to produce encapsulated micelles directly from block copolymer solutions is demonstrated with a throughput of 1.2 g of micelles per hour. | Document URI: | http://hdl.handle.net/1942/36239 | ISSN: | 0024-9297 | e-ISSN: | 1520-5835 | DOI: | 10.1021/acs.macromol.1c00242 | ISI #: | 000645430100026 | Rights: | 2021 American Chemical Society | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2022 |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Template for Electronic Submission to ACS Journals.pdf | Peer-reviewed author version | 958.63 kB | Adobe PDF | View/Open |
Micelle Purification in Continuous Flow via Inline Dialysis.pdf Restricted Access | Published version | 2.55 MB | Adobe PDF | View/Open Request a copy |
WEB OF SCIENCETM
Citations
10
checked on Oct 14, 2024
Page view(s)
34
checked on Sep 7, 2022
Download(s)
48
checked on Sep 7, 2022
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.