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http://hdl.handle.net/1942/4030
Title: | Comparison of different estimation procedures for proportional hazards model with random effects | Authors: | CORTINAS ABRAHANTES, Jose LEGRAND, Catherine BURZYKOWSKI, Tomasz JANSSEN, Paul Ducrocq, Vincent DUCHATEAU, Luc |
Issue Date: | 2007 | Publisher: | ELSEVIER SCIENCE BV | Source: | COMPUTATIONAL STATISTICS & DATA ANALYSIS, 51(8). p. 3913-3930 | Abstract: | Proportional hazards models with multivariate random effects (frailties) acting multiplicatively on the baseline hazard are a topic of intensive research. Several estimation procedures have been proposed to deal with this type of models. Four procedures used to fit these models are compared in two real-life datasets and in a simulation study. The performance of the four methods is investigated in terms of the bias of point estimates, their empirical variability and the bias of the estimation of the variability. (c) 2006 Elsevier B.V. All rights reserved. | Notes: | Hasselt Univ, Ctr Stat, B-3590 Diepenbeek, Belgium. European Org Res Treatment Canc, B-1200 Brussels, Belgium. INRA, Stn Genet Quantitat & Appl, F-78352 Jouy En Josas, France. Univ Ghent, Fac Med Vet, Dept Physiol Biochem & Biometr, B-9820 Merelbeke, Belgium.Abrahantes, JC, Hasselt Univ, Ctr Stat, Agoralaan D, B-3590 Diepenbeek, Belgium.jose.cortinas@uhasselt.be | Keywords: | frailty model; restricted or residual maximum likelihood; penalized partial likelihood; laplace approximation; multivariate failure-time data | Document URI: | http://hdl.handle.net/1942/4030 | ISSN: | 0167-9473 | e-ISSN: | 1872-7352 | DOI: | 10.1016/j.csda.2006.03.009 | ISI #: | 000246128500022 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2008 |
Appears in Collections: | Research publications |
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