Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/8552
Title: | Penicillin detection with nanocrystalline-diamond field-effect sensor | Authors: | Abouzar, Maryam H. Poghossian, Arshak Razavi, Arash Besmehn, Astrid BIJNENS, Nathalie WILLIAMS, Oliver HAENEN, Ken WAGNER, Patrick Schoening, Michael J. |
Issue Date: | 2008 | Publisher: | WILEY-V C H VERLAG GMBH | Source: | PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE, 205(9). p. 2141-2145 | Abstract: | Nanocrystalline-diamond (NCD) films have been utilised for the detection of penicillin G for the first time. The developed penicillin-sensitive biosensor consists of a field-effect capacitive electrolyte-diamond-insulator-semiconductor (EDIS) structure with an immobilised enzyme layer that covers the gate region of the sensor. Undoped NCD thin films of about 100 nm thickness were grown on a p-Si-SiO2 (50 nm thermally grown SiO2) structure by microwave plasma-enhanced chemical vapour deposition. The enzyme penicillinase has been adsorptively immobilised directly onto the O-terminated NCD surface. The EDIS biosensors have been characterised in buffer solutions with different content of penicillin G by means of capacitance-voltage and constant-capacitance method. The developed penicillin biosensor possesses a low detection limit of 5 mu M and a high sensitivity of 6070 mV/decade in a wide linear range of 0.005-2.5 mM penicillin G concentration. (C) 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. | Notes: | [Abouzar, Maryam H.; Poghossian, Arshak; Razavi, Arash; Schoening, Michael J.] Aachen Univ Appl Sci, INB, D-52428 Julich, Germany. [Abouzar, Maryam H.; Poghossian, Arshak; Razavi, Arash; Schoening, Michael J.] Res Ctr Julich GmbH, Inst Bio & Nanosyst IBN 2, D-52425 Julich, Germany. [Bijnens, Nathalile; Williams, Oliver A.; Haenen, Ken; Wagner, Patrick] Hasselt Univ, Inst Mat Res, B-3590 Diepenbeek, Belgium. [Williams, Oliver A.; Haenen, Ken] IMEC VZW, Div IMOMEC, B-3590 Diepenbeek, Belgium. [Besmehn, Astrid] Res Ctr Julich GmbH, Cent Div Analyt Chem ZCH, D-52425 Julich, Germany. | Document URI: | http://hdl.handle.net/1942/8552 | ISSN: | 1862-6300 | e-ISSN: | 1862-6319 | DOI: | 10.1002/pssa.200879713 | ISI #: | 000259653700008 | Category: | A1 | Type: | Journal Contribution | Validations: | ecoom 2009 |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Abouzar.pdf | Non Peer-reviewed author version | 273.01 kB | Adobe PDF | View/Open |
SCOPUSTM
Citations
22
checked on Sep 3, 2020
WEB OF SCIENCETM
Citations
25
checked on Oct 12, 2024
Page view(s)
62
checked on Sep 5, 2022
Download(s)
194
checked on Sep 5, 2022
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.