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| | Issue Date | Title | Contributor(s) | Type | Cat. |
| 1 | 2024 | The sphingosine-1-phosphate receptor 1 modulator ponesimod repairs cuprizone-induced demyelination and induces oligodendrocyte differentiation | WILLEMS, Emily; SCHEPERS, Melissa; PICCART, Elisabeth; WOLFS, Esther; HELLINGS, Niels; Ait-Tihyaty, Maria; VANMIERLO, Tim | Journal Contribution | A1 |
| 2 | 2024 | Rapamycin rescues loss of function in blood-brain barrier–interacting Tregs | BAETEN, Paulien; HAMAD, Ibrahim; HOEKS, Cindy; Hiltensperger, Michael; VAN WIJMEERSCH, Bart; POPESCU, Veronica; Aly, Lilian; SOMERS, Veerle; Korn, Thomas; KLEINEWIETFELD, Markus; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | A1 |
| 3 | 2024 | The Impact of Sample Storage on Blood Methylation: Towards Assessing Myelin Gene Methylation as a Biomarker for Progressive Multiple Sclerosis | TIANE, Assia; SOMERS, Veerle; HELLINGS, Niels; van den Hove, DLA; VANMIERLO, Tim | Journal Contribution | A1 |
| 4 | 2023 | Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury | Mussen, Femke; VAN BROECKHOVEN, Jana; HELLINGS, Niels; SCHEPERS, Melissa; VANMIERLO, Tim | Journal Contribution | A1 |
| 5 | 2023 | Phosphodiesterase (PDE) 4 inhibition boosts Schwann cell myelination in a 3D regeneration model | SCHEPERS, Melissa; Malheiro, Afonso; Gamardo, Adrian Seijas; HELLINGS, Niels; Prickaerts, Jos; Moroni, Lorenzo; VANMIERLO, Tim; Wieringa, Paul | Journal Contribution | A1 |
| 6 | 2023 | From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions | TIANE, Assia; SCHEPERS, Melissa; Reijnders, Rick A.; VAN VEGGEL, Lieve; CHENINE, Sarah; ROMBAUT, Ben; Dempster, Emma; Verfaillie, Catherine; Wasner, Kobi; Gruenewald, Anne; Prickaerts, Jos; Pishva, Ehsan; HELLINGS, Niels; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A1 |
| 7 | 2023 | Differential Runx3, Eomes, and T-bet expression subdivides MS-associated CD4+ T cells with brain-homing capacity | HOEKS, Cindy; van Puijfelik, Fabienne; Koetzier, Steven C.; Rip, Jasper; Corsten, Cato E. A.; Wierenga-Wolf, Annet F.; Melief, Marie-Jose; STINISSEN, Piet; Smolders, Joost; HELLINGS, Niels; BROUX, Bieke; van Luijn, Marvin M. | Journal Contribution | A1 |
| 8 | 2023 | A perspective on causality assessment in epigenetic research on neurodegenerative disorders | KOULOUSAKIS, Philippos; TIANE, Assia; HELLINGS, Niels; Prickaerts, Jos; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A2 |
| 9 | 2023 | Differential Runx3, Eomes, and T-bet expression subdivides cytotoxic CD4+memory T cells with brain-homing capacity | HOEKS, Cindy; van Puijfelik, Fabienne; Koetzier, Steven; Rip, Jasper; Corsten, Cato; Wierenga-Wolf, Annet; Melief, Marie-Jose; STINISSEN, Piet; Smolders, Joost; HELLINGS, Niels; BROUX, Bieke; van Luijn, Marvin | Journal Contribution | M |
| 10 | 2023 | Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis | SCHEPERS, Melissa; PAES, Dean; TIANE, Assia; ROMBAUT, Ben; PICCART, Elisabeth; VAN VEGGEL, Lieve; GERVOIS, Pascal; Brullo, Chiara; Bruno, Olga; Fedele, Ernesto; Ricciarelli, Roberta; Ffrench-Constant, Charles; Bechler, Marie E.; Schaik, Pauline van; WOLFS, Esther; LAMBRICHTS, Ivo; Baron, Wia; LEFEVERE, Evy; Wasner, Kobi; Gruenewald, Anne; Verfaillie, Catherine; Wieringa, Paul; Prickaerts, Jos; BROUX, Bieke; BAETEN, Paulien; HELLINGS, Niels; VANMIERLO, Tim | Journal Contribution | A1 |
| 11 | 2023 | Comprehensive antibody and cytokine profiling in hospitalized COVID-19 patients in relation to clinical outcomes in a large Belgian cohort | RUYTINX, Pieter; VANDORMAEL, Patrick; FRAUSSEN, Judith; PIETERS, Zoe; Thonissen, Stef; HELLINGS, Niels; STINISSEN, Piet; CALLEBAUT, Ina; PENDERS, Joris; VANHOVE, Karolien; Kieffer, Davy; RUMMENS, Jean-Luc; Valkenborgh, Tom; MESSIAEN, Peter; STESSEL, Bjorn; MESOTTEN, Dieter; SOMERS, Veerle | Journal Contribution | A1 |
| 12 | 2023 | Cerebral microvascular endothelial cell-derived extracellular vesicles regulate blood - brain barrier function | HOSSEINKHANI, Baharak; DURAN, Gayel; HOEKS, Cindy; HERMANS, Doryssa; SCHEPERS, Melissa; BAETEN, Paulien; POELMANS, Joren; Coenen, Britt; Bekar, Kuebra; Pintelon, Isabel; Timmermans , Jean-Pierre; VANMIERLO, Tim; MICHIELS, Luc; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | A1 |
| 13 | 2023 | Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS | Pegoretti, Valentina; Bauer, Jan; Fischer, Roman; Paro, Iskra; Douwenga, Wanda; Kontermann, Roland E.; Pfizenmaier, Klaus; HOUBEN, Evelien; BROUX, Bieke; HELLINGS, Niels; Baron, Wia; Laman, Jon D.; Eisel, Ulrich L. M. | Journal Contribution | A1 |
| 14 | 2023 | Effects of Recombinant IL-13 Treatment on Gut Microbiota Composition and Functional Recovery after Hemisection Spinal Cord Injury in Mice | HAMAD, Ibrahim; VAN BROECKHOVEN, Jana; CARDILLI, Alessio; HELLINGS, Niels; Strowig, Till; LEMMENS, Stefanie; HENDRIX, Sven; KLEINEWIETFELD, Markus | Journal Contribution | A1 |
| 15 | 2023 | Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity | GRAJCHEN, Elien; LOIX, Melanie; BAETEN, Paulien; FERNANDES CORTE-REAL, Beatriz; HAMAD, Ibrahim; VANHERLE, Sam; HAIDAR, Mansour; Dehairs, Jonas; Broos, Jelle Y.; Ntambi, James M.; Zimmermann, Robert; Breinbauer, Rolf; STINISSEN, Piet; HELLINGS, Niels; Verberk, Sanne G. S.; Kooij, Gijs; Giera, Martin; Swinnen, Johannes V.; BROUX, Bieke; KLEINEWIETFELD, Markus; HENDRIKS, Jerome; BOGIE, Jeroen | Journal Contribution | A1 |
| 16 | 2023 | Sodium perturbs mitochondrial respiration and induces dysfunctional Tregs | FERNANDES CORTE-REAL, Beatriz; HAMAD, Ibrahim; ARROYO HORNERO, Rebeca; Geisberger, Sabrina; Roels, Joris; VAN ZEEBROECK, Lauren; DYCZKO, Aleksandra; van Gisbergen, Marike W.; Kurniawan, Henry; Wagner, Allon; Yoset, Nir; Weiss, Susanne N. Y.; Schmetterer, Klaus G.; Schroeder, Agnes; Krampert, Luka; Haase, Stefanie; Bartolomaeus, Hendrik; HELLINGS, Niels; Saeys, Yvan; Dubois, Ludwig J.; Brenner, Dirk; Kempa, Stefan; Hafler, David A.; Stegbauer, Johannes; Linker, Ralf A.; Jantsch, Jonathan; Mueller, Dominik N.; KLEINEWIETFELD, Markus | Journal Contribution | A1 |
| 17 | 2023 | Carnosine synthase deficiency aggravates neuroinflammation in multiple sclerosis | SPAAS, Jan; Van der Stede, Thibaux; de Jager, Sarah; VAN DE WATERWEG BERENDS, Annet; TIANE, Assia; Baelde, Hans; Baba, Shahid P.; Eckhardt, Matthias; WOLFS, Esther; VANMIERLO, Tim; HELLINGS, Niels; OP 'T EIJNDE, Bert; Derave, Wim | Journal Contribution | A1 |
| 18 | 2023 | Train your T cells: How skeletal muscles and T cells keep each other fit during aging | SLAETS, Leen; FONTEYN, Lena; OP 'T EIJNDE, Bert; HELLINGS, Niels | Journal Contribution | A1 |
| 19 | 2022 | When Helpers Go Above and Beyond: Development and Characterization of Cytotoxic CD4(+) T Cells | HOEKS, Cindy; DURAN, Gayel; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | A1 |
| 20 | 2022 | L-Arginine Depletion Improves Spinal Cord Injury via Immunomodulation and Nitric Oxide Reduction | ERENS, Celine; VAN BROECKHOVEN, Jana; HOEKS, Cindy; Schabbauer, Gernot; Cheng, Paul; Chen, Li; HELLINGS, Niels; BROUX, Bieke; LEMMENS, Stefanie; HENDRIX, Sven | Journal Contribution | A1 |
| 21 | 2022 | Oligodendroglia-derived extracellular vesicles activate autophagy via LC3B/BAG3 to protect against oxidative stress with an enhanced effect for HSPB8 enriched vesicles | VAN DEN BROEK, Bram; Wuyts, Charlotte; Sisto, Angela; Pintelon, Isabel; Timmermans, Jean-Pierre; SOMERS, Veerle; Timmerman, Vincent; HELLINGS, Niels; IROBI, Joy | Journal Contribution | A1 |
| 22 | 2022 | Development of a stable autologous regulatory T cell-based cell therapy for multiple sclerosis | BAETEN, Paulien; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | M |
| 23 | 2022 | Improving the Efficacy of Regulatory T Cell Therapy | BAETEN, Paulien; VAN ZEEBROECK, Lauren; KLEINEWIETFELD, Markus; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | A1 |
| 24 | 2022 | Studying the clinical, radiological, histological, microbiological, and immunological evolution during the different COVID-19 disease stages using minimal invasive autopsy | D'ONOFRIO, Valentino; Keulen, Lotte; Vandendriessche, Annelore; Dubois, Jasperina; Cartuyvels, Reinoud; Vanden Abeele, Marie-Elena; FRAUSSEN, Judith; VANDORMAEL, Patrick; SOMERS, Veerle; ACHTEN, Ruth; Dendooven, Amélie; DRIESSEN, Ann; Augsburg, Lukasz; HELLINGS, Niels; Lammens, Martin; Vanrusselt, Jan; COX, Janneke | Journal Contribution | A1 |
| 25 | 2022 | Oncostatin M triggers brain inflammation by compromising blood-brain barrier integrity | HERMANS, Doryssa; HOUBEN, Evelien; BAETEN, Paulien; Slaets, Helena; JANSSENS, Kris; HOEKS, Cindy; HOSSEINKHANI, Baharak; DURAN, Gayel; BORMANS, Seppe; Gowing, Elizabeth; Hoornaert , Chloe; BECKERS, Lien; Fung, Wing Ka; Schroten, Horst; Ishikawa, Hiroshi; FRAUSSEN, Judith; THOELEN, Ronald; de Vries, Helga E.; Kooij, Gijs; Zandee, Stephanie; Prat, Alexandre; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | A1 |
| 26 | 2022 | Rapamycin rescues loss-of-function in blood-brain barrier-interacting regulatory T cells | BAETEN, Paulien; HAMAD, Ibrahim; HOEKS, Cindy; Hiltensperger, Michael; VAN WIJMEERSCH, Bart; POPESCU, Veronica; Aly, Lilian; SOMERS, Veerle; Korn, Thomas; KLEINEWIETFELD, Markus; HELLINGS, Niels; BROUX, Bieke | Preprint | O |
| 27 | 2021 | Oncostatin M opens the gate for T helper 17 cells during neuroinflammation | HERMANS, Doryssa; HOUBEN, Evelien; BAETEN, Paulien; HOSSEINKHANI, Baharak; BORMANS, Seppe; THOELEN, Ronald; De Vries , Elga; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | M |
| 28 | 2021 | DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation. | TIANE, Assia; SCHEPERS, Melissa; Riemens, R.; ROMBAUT, Ben; VANDORMAEL, Patrick; SOMERS, Veerle; Prickaerts, J.; HELLINGS, Niels; Van den Hove, D.; VANMIERLO, Tim | Journal Contribution | M |
| 29 | 2021 | Treg-Resistant Cytotoxic CD4+ T Cells Dictate T Helper Cells in Their Vicinity: TH17 Skewing and Modulation of Proliferation | HOEKS, Cindy; VANHEUSDEN, Marjan; PEETERS, Liesbet; STINISSEN, Piet; BROUX, Bieke; HELLINGS, Niels | Journal Contribution | A1 |
| 30 | 2021 | DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation | TIANE, Assia; SCHEPERS, Melissa; Riemens, Renzo; ROMBAUT, Ben; VANDORMAEL, Patrick; SOMERS, Veerle; Prickaerts, Jos; HELLINGS, Niels; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A1 |
| 31 | 2021 | Efficacy and safety of spore-forming probiotics in the treatment of functional dyspepsia: a pilot randomised, double-blind, placebo-controlled trial | Wauters, Lucas; SLAETS, Leen; De Paepe, Kim; Ceulemans, Matthias; WETZELS, Suzan; Geboers, Karlien; Toth, Joran; Thys, Wannes; Dybajlo, Raf; Walgraeve, Daan; Biessen, Erik; Verbeke, Kristin; Tack, Jan; Wiele, Tom Van de; HELLINGS, Niels; Vanuytsel, Tim | Journal Contribution | A1 |
| 32 | 2021 | Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders | SPAAS, Jan; VAN VEGGEL, Lieve; SCHEPERS, Melissa; TIANE, Assia; VAN HORSSEN, Jack; WILSON, David; Moya, Pablo R.; PICCART, Elisabeth; HELLINGS, Niels; OP 'T EIJNDE, Bert; Derave, Wim; Schreiber, Rudy; VANMIERLO, Tim | Journal Contribution | A1 |
| 33 | 2021 | Multiple Sclerosis Data Alliance - A global multi-stakeholder collaboration to scale-up real world data research | PEETERS, Liesbet; PARCIAK, Tina; Kalra, Dipak; Moreau, Yves; Kasilingam, Elisabeth; Galen, Pieter van; Thalheim, Christoph; Uitdehaag, Bernard; Vermersch, Patrick; HELLINGS, Niels; STINISSEN, Piet; VAN WIJMEERSCH, Bart; Ardeshirdavani, Amin; PIRMANI, Ashkan; Brouwer, Edward De; Bauer, Christian Robert; Krefting, Dagmar; Ribbe, Stephanie; Middleton, Rod; Stahmann, Alexander; Comi, Giancarlo | Journal Contribution | A1 |
| 34 | 2021 | Carnosine quenches the reactive carbonyl acrolein in the central nervous system and attenuates autoimmune neuroinflammation | SPAAS, Jan; FRANSSEN, Wouter; KEYTSMAN, Charly; Blancquaert, Laura; VANMIERLO, Tim; BOGIE, Jeroen; BROUX, Bieke; HELLINGS, Niels; VAN HORSSEN, Jack; Posa, Dheeraj Kumar; Hoetker, David; Baba, Shahid P.; Derave, Wim; OP 'T EIJNDE, Bert | Journal Contribution | A1 |
| 35 | 2021 | PEGylating poly(p-phenylene vinylene)-based bioimaging nanoprobes | PETERS, Martijn; DESTA, Derese; SENECA, Senne; REEKMANS, Gunter; ADRIAENSENS, Peter; NOBEN, Jean-Paul; HELLINGS, Niels; JUNKERS, Tanja; ETHIRAJAN, Anitha | Journal Contribution | A1 |
| 36 | 2020 | In Vitro Tailoring of Regulatory T Cells Prior to Cell Therapy | BAETEN, Paulien; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | A2 |
| 37 | 2020 | Editorial: Neuro-Immune Connections to Enable Repair in CNS Disorders | VANMIERLO, Tim; VAN HORSSEN, Jack; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | A1 |
| 38 | 2020 | Sphingosine-1-Phosphate Receptor Modulators and Oligodendroglial Cells: Beyond Immunomodulation | Roggeri, Alessandra; SCHEPERS, Melissa; TIANE, Assia; ROMBAUT, Ben; VAN VEGGEL, Lieve; HELLINGS, Niels; Prickaerts, Jos; Pittaluga, Anna; VANMIERLO, Tim | Journal Contribution | A1 |
| 39 | 2020 | Neutrophils: Underestimated Players in the Pathogenesis of Multiple Sclerosis (MS) | DE BONDT, Mirre; HELLINGS, Niels; OPDENAKKER, Ghislain; Struyf, Sofie | Journal Contribution | A1 |
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