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| | Issue Date | Title | Contributor(s) | Type | Cat. |
| 1 | 2024 | Novel insights in phosphodiesterase 4 subtype inhibition to target neuroinflammation and stimulate remyelination | SCHEPERS, Melissa; VANMIERLO, Tim | Journal Contribution | A2 |
| 2 | 2024 | The sphingosine-1-phosphate receptor 1 modulator ponesimod repairs cuprizone-induced demyelination and induces oligodendrocyte differentiation | WILLEMS, Emily; SCHEPERS, Melissa; PICCART, Elisabeth; WOLFS, Esther; HELLINGS, Niels; Ait-Tihyaty, Maria; VANMIERLO, Tim | Journal Contribution | A1 |
| 3 | 2023 | Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury | Mussen, Femke; VAN BROECKHOVEN, Jana; HELLINGS, Niels; SCHEPERS, Melissa; VANMIERLO, Tim | Journal Contribution | A1 |
| 4 | 2023 | Phosphodiesterase (PDE) 4 inhibition boosts Schwann cell myelination in a 3D regeneration model | SCHEPERS, Melissa; Malheiro, Afonso; Gamardo, Adrian Seijas; HELLINGS, Niels; Prickaerts, Jos; Moroni, Lorenzo; VANMIERLO, Tim; Wieringa, Paul | Journal Contribution | A1 |
| 5 | 2023 | Ablation of specific long PDE4D isoforms increases neurite elongation and conveys protection against amyloid-beta pathology | PAES, Dean; SCHEPERS, Melissa; WILLEMS, Emily; ROMBAUT, Ben; TIANE, Assia; Solomina, Yevgeniya; Tibbo, Amy; Blair, Connor; Kyurkchieva, Elka; Baillie, George S.; Ricciarelli, Roberta; Brullo, Chiara; Fedele, Ernesto; Bruno, Olga; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos | Journal Contribution | A1 |
| 6 | 2023 | From methylation to myelination: epigenomic and transcriptomic profiling of chronic inactive demyelinated multiple sclerosis lesions | TIANE, Assia; SCHEPERS, Melissa; Reijnders, Rick A.; VAN VEGGEL, Lieve; CHENINE, Sarah; ROMBAUT, Ben; Dempster, Emma; Verfaillie, Catherine; Wasner, Kobi; Gruenewald, Anne; Prickaerts, Jos; Pishva, Ehsan; HELLINGS, Niels; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A1 |
| 7 | 2023 | Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment? | NELISSEN, Ellis; SCHEPERS, Melissa; PONSAERTS, Laura; Foulquier, Sebastien; BRONCKAERS, Annelies; VANMIERLO, Tim; Sandner, Peter; Prickaerts, Jos | Journal Contribution | A1 |
| 8 | 2023 | Exogenous Oxytocin Administration Restores Memory in Female APP/PS1 Mice | KOULOUSAKIS, Philippos; WILLEMS, Emily; SCHEPERS, Melissa; ROMBAUT, Ben; Prickaerts, Jos; VANMIERLO, Tim; van den Hove, Daniel | Journal Contribution | A1 |
| 9 | 2023 | Selective PDE4 subtype inhibition provides new opportunities to intervene in neuroinflammatory versus myelin damaging hallmarks of multiple sclerosis | SCHEPERS, Melissa; PAES, Dean; TIANE, Assia; ROMBAUT, Ben; PICCART, Elisabeth; VAN VEGGEL, Lieve; GERVOIS, Pascal; Brullo, Chiara; Bruno, Olga; Fedele, Ernesto; Ricciarelli, Roberta; Ffrench-Constant, Charles; Bechler, Marie E.; Schaik, Pauline van; WOLFS, Esther; LAMBRICHTS, Ivo; Baron, Wia; LEFEVERE, Evy; Wasner, Kobi; Gruenewald, Anne; Verfaillie, Catherine; Wieringa, Paul; Prickaerts, Jos; BROUX, Bieke; BAETEN, Paulien; HELLINGS, Niels; VANMIERLO, Tim | Journal Contribution | A1 |
| 10 | 2023 | Cerebral microvascular endothelial cell-derived extracellular vesicles regulate blood - brain barrier function | HOSSEINKHANI, Baharak; DURAN, Gayel; HOEKS, Cindy; HERMANS, Doryssa; SCHEPERS, Melissa; BAETEN, Paulien; POELMANS, Joren; Coenen, Britt; Bekar, Kuebra; Pintelon, Isabel; Timmermans , Jean-Pierre; VANMIERLO, Tim; MICHIELS, Luc; HELLINGS, Niels; BROUX, Bieke | Journal Contribution | A1 |
| 11 | 2023 | PDE4 gene inhibition - a novel approach to treat demyelinating disorders | SCHEPERS, Melissa | Theses and Dissertations | T1 |
| 12 | 2022 | Ponesimod, mono-selective sphingosine-1-phosphate receptor 1 modulator enhances oligodendrocyte precursor cell differentiation | WILLEMS, Emily; SCHEPERS, Melissa; Ait-Tihyaty, M.; VANMIERLO, Tim | Journal Contribution | M |
| 13 | 2022 | The monoselective sphingosine-1-phosphate receptor-1 modulator ponesimod enhances remyelination in the cuprizone model of demyelination | SCHEPERS, Melissa; WILLEMS, Emily; Ait-Tihyaty, M.; VANMIERLO, Tim | Journal Contribution | M |
| 14 | 2022 | The sGC stimulator BAY-747 and activator runcaciguat can enhance memory in vivo via differential hippocampal plasticity mechanisms | NELISSEN, Ellis; Possemis, Nina; Van Goethem, Nick P.; SCHEPERS, Melissa; Mulder-Jongen, Danielle A. J.; Dietz, Lisa; JANSSEN, Wiebke; Gerisch, Michael; Huser, Jorg; Sandner, Peter; VANMIERLO, Tim; Prickaerts, Jos | Journal Contribution | A1 |
| 15 | 2022 | THE USE OF SEAWEED-DERIVED PHYTOSTEROLS TO DEFEAT ALZHEIMER'S DISEASE | MARTENS, Nikita; SCHEPERS, Melissa; ZHAN, Na; Leijten, F.; Voortman-Minderman, G.; TIANE, Assia; ROMBAUT, Ben; Poisquet, Janne; Van de Sande, N.; Kerksiek, A.; Kuipers, F.; Jonker, J. W.; Liu, H.; Luetjohann, D.; VANMIERLO, Tim; Mulder, M. T. | Journal Contribution | M |
| 16 | 2022 | The Selective Sphingosine-1-Phosphate Receptor 1 (S1P1) Modulator Ponesimod Enhances Murine Oligodendrocyte Precursor Cell (OPC) Differentiation and Retains OPC Migration | Ait-Tihyaty, M.; PICCART, Elisabeth; SCHEPERS, Melissa; WILLEMS, E; DiBernardo, A.; VANMIERLO, Tim | Journal Contribution | M |
| 17 | 2022 | INCREASING CAMP LEVELS BY INHIBITING PHOSPHODIESTERASE 4D IMPROVES NERVE CONDUCTION AND FUNCTIONAL RECOVERY IN A MOUSE MODEL FOR CHARCOT MARIE TOOT 1A | VANGANSEWINKEL, Tim; SCHEPERS, Melissa; LIBBERECHT, Karen; Jacobs , Darren; PICCART, Elisabeth; JEURISSEN, Hanne; Prior, Robert; Ricciarelli, Roberta; Bruno, Olga; Fedele, Ernesto; Brullo, Chiara; Prickaerts, Jos; Van Den Bosch , Ludo; VANMIERLO, Tim; LAMBRICHTS, Ivo; WOLFS, Esther | Journal Contribution | M |
| 18 | 2021 | DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation. | TIANE, Assia; SCHEPERS, Melissa; Riemens, R.; ROMBAUT, Ben; VANDORMAEL, Patrick; SOMERS, Veerle; Prickaerts, J.; HELLINGS, Niels; Van den Hove, D.; VANMIERLO, Tim | Journal Contribution | M |
| 19 | 2021 | Neuroinflammation in Ischemic Stroke: Inhibition of cAMP-Specific Phosphodiesterases (PDEs) to the Rescue | PONSAERTS, Laura; ALDERS, Lotte; SCHEPERS, Melissa; de Oliveira, RMW; Prickaerts, J; VANMIERLO, Tim; BRONCKAERS, Annelies | Journal Contribution | A1 |
| 20 | 2021 | 24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer’s Disease | MARTENS, Nikita; SCHEPERS, Melissa; Zhan, Na; Leijten, Frank; Voortman, Gardi; TIANE, Assia; ROMBAUT, Ben; POISQUET, Janne; van de Sande, Nienke; Kerksiek, Anja; Kuipers, Folkert; Jonker, Johan W.; Liu, Hongbing; Lütjohann, Dieter; VANMIERLO, Tim; Mulder, Monique T. | Journal Contribution | A1 |
| 21 | 2021 | Positive effects of roflumilast on behavior, neuroinflammation, and white matter injury in mice with global cerebral ischemia | Vilhena, Emanuella R.; Bonato, Jessica M.; SCHEPERS, Melissa; Kunieda, Juliana K. C.; Milani, Humberto; VANMIERLO, Tim; Prickaerts, Jos; de Oliveira, Rubia M. W. | Journal Contribution | A1 |
| 22 | 2021 | The Molecular Biology of Phosphodiesterase 4 Enzymes as Pharmacological Targets: An Interplay of Isoforms, Conformational States, and Inhibitors | PAES, Dean; SCHEPERS, Melissa; ROMBAUT, Ben; van den Hove, Daniel; VANMIERLO, Tim; Prickaerts, Jos; Michel, Martin | Journal Contribution | A1 |
| 23 | 2021 | DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation | TIANE, Assia; SCHEPERS, Melissa; Riemens, Renzo; ROMBAUT, Ben; VANDORMAEL, Patrick; SOMERS, Veerle; Prickaerts, Jos; HELLINGS, Niels; van den Hove, Daniel; VANMIERLO, Tim | Journal Contribution | A1 |
| 24 | 2021 | PDE inhibition in distinct cell types to reclaim the balance of synaptic plasticity | ROMBAUT, Ben; KESSELS, Sofie; SCHEPERS, Melissa; TIANE, Assia; PAES, Dean; Solomina, Yevgeniya; PICCART, Elisabeth; van den Hove, Daniel; BRONE, Bert; Prickaerts, Jos; VANMIERLO, Tim | Journal Contribution | A1 |
| 25 | 2021 | Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders | SPAAS, Jan; VAN VEGGEL, Lieve; SCHEPERS, Melissa; TIANE, Assia; VAN HORSSEN, Jack; WILSON, David; Moya, Pablo R.; PICCART, Elisabeth; HELLINGS, Niels; OP 'T EIJNDE, Bert; Derave, Wim; Schreiber, Rudy; VANMIERLO, Tim | Journal Contribution | A1 |
| 26 | 2021 | 24(R, S)-Saringosterol - From artefact to a biological medical agent | VANBRABANT, Kenneth; Van Meel, David; Kerksiek, Anja; Friedrichs, Silvia; Dubbeldam, Marco; SCHEPERS, Melissa; Zhan, Na; Gutbrod, Katharina; Dörmann, Peter; Liu, Hong-Bing; Mulder, Monique T; VANMIERLO, Tim; Lütjohann, Dieter | Journal Contribution | A1 |
| 27 | 2021 | Corrigendum: Edible seaweed-derived constituents: an undisclosed source of neuroprotective compounds | SCHEPERS, Melissa; MARTENS, Nikita; TIANE, Assia; VANBRABANT, Kenneth; Liu, Hong-Bing; Lütjohann, Dieter; Mulder, Monique; VANMIERLO, Tim | Journal Contribution | M |
| 28 | 2021 | Increased isoform-specific phosphodiesterase 4D expression is associated with pathology and cognitive impairment in Alzheimer’s disease | PAES, Dean; Lardenoije, Roy; CAROLLO, Riccardo; Roubroeks, Janou A. Y.; SCHEPERS, Melissa; Coleman, Paul; Mastroeni, Diego; Delvaux, Elaine; Pishva, Ehsan; Lunnon, Katie; VANMIERLO, Tim; van den Hove, Daniel; Prickaerts, Jos | Journal Contribution | A1 |
| 29 | 2020 | Sphingosine-1-Phosphate Receptor Modulators and Oligodendroglial Cells: Beyond Immunomodulation | Roggeri, Alessandra; SCHEPERS, Melissa; TIANE, Assia; ROMBAUT, Ben; VAN VEGGEL, Lieve; HELLINGS, Niels; Prickaerts, Jos; Pittaluga, Anna; VANMIERLO, Tim | Journal Contribution | A1 |
| 30 | 2020 | Edible seaweed-derived constituents: an undisclosed source of neuroprotective compounds | SCHEPERS, Melissa; MARTENS, Nikita; TIANE, Assia; VANBRABANT, Kenneth; Liu, Hong-Bing; Lütjohann, Dieter; Mulder, Monique; VANMIERLO, Tim | Journal Contribution | A1 |
| 31 | 2020 | Oncostatin m-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination | HOUBEN, Evelien; JANSSENS, Kris; HERMANS, Doryssa; Vandooren, J.; Van den Haute, C.; SCHEPERS, Melissa; VANMIERLO, Tim; LAMBRICHTS, Ivo; Baekelandt, V.; VAN HORSSEN, Jack; Baron, W.; OPDENAKKER, Ghislain; BROUX, Bieke; SLAETS, Leen; HELLINGS, Niels | Journal Contribution | M |
| 32 | 2020 | Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination | HOUBEN, Evelien; JANSSENS, Kris; HERMANS, Doryssa; Vandooren, Jennifer; Van den Haute, Chris; SCHEPERS, Melissa; VANMIERLO, Tim; LAMBRICHTS, Ivo; VAN HORSSEN, Jack; Baekelandt, Veerle; OPDENAKKER, Ghislain; Baron, Wia; BROUX, Bieke; Slaets, Helena; HELLINGS, Niels | Journal Contribution | A1 |
| 33 | 2019 | DIETARY SARGASSUM FUSIFORME IMPROVES MEMORY AND REDUCES AMYLOID PLAQUE LOAD IN AN ALZHEIMER'S DISEASE MOUSE MODEL | Mulder, M.; BOGIE, Jeroen; HOEKS, Cindy; SCHEPERS, Melissa; Tuabe, A.; Leijten, F.; Chintapakorn, Y.; Struik, D.; Liu, H. B.; HELLINGS, Niels; Martinez-Martinez, P.; Jonker, J.; DEWACHTER, Ilse; Walter, J.; HENDRIKS, Jerome; Groen, A.; Staels, B.; Lutjohann, D.; VANMIERLO, Tim | Journal Contribution | M |
| 34 | 2019 | Relieving the epigenetic blockade in progressive multiple sclerosis - making remyelination accessible again | TIANE, Assia; SCHEPERS, Melissa; PAES, Dean; Prickaerts, J.; van den Hove, D.; HELLINGS, Niels; VANMIERLO, Tim | Journal Contribution | M |
| 35 | 2019 | Sargassum fusiforme improves memory and reduces amyloid plaque pathology in an Alzheimer's disease mouse model | BOGIE, Jeroen; HOEKS, Cindy; SCHEPERS, Melissa; TIANE, Assia; CUYPERS, Ann; Leijten, F.; Chintapakorn, Y.; Suttyut, T.; Pornpakakul, S.; Struik, D.; Kerksiek, A.; Liu, H.; HELLINGS, Niels; Martinez-Marinez, P.; Jonker, J.; DEWACHTER, Ilse; Sijbrands, E.; Walter, J.; HENDRIKS, Jerome; Groen, A.; Staels, B.; Luetjohann, D.; Mulder, M.; VANMIERLO, Tim | Journal Contribution | M |
| 36 | 2019 | Phosphodiesterase 4D inhibition boosts remyelination in multiple sclerosis | SCHEPERS, Melissa; PAES, Dean; TIANE, Assia; HOUBEN, Els; Bruno, O.; Brullo, C.; HELLINGS, Niels; Prickaerts, J.; VANMIERLO, Tim | Journal Contribution | M |
| 37 | 2019 | Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model | BOGIE, Jeroen; HOEKS, Cindy; SCHEPERS, Melissa; TIANE, Assia; CUYPERS, Ann; Leijten, Frank; Chintapakorn, Yupyn; Suttiyut, Thiti; Pornpakakul, Surachai; Struik, Dicky; Kerksiek, Anja; Liu, Hong-Bing; HELLINGS, Niels; Martinez-Martinez, Pilar; Jonker, Johan W.; DEWACHTER, Ilse; Sijbrands, Eric; Walter, Jochen; HENDRIKS, Jerome; Groen, Albert; Staels, Bart; Lutjohann, Dieter; VANMIERLO, Tim; Mulder, Monique | Journal Contribution | A1 |
| 38 | 2019 | From OPC to Oligodendrocyte: An Epigenetic Journey | TIANE, Assia; SCHEPERS, Melissa; ROMBAUT, Ben; Hupperts, R; Prickaerts, J; HELLINGS, Niels; van den Hove, D; VANMIERLO, Tim | Journal Contribution | A1 |
| 39 | 2019 | Targeting Phosphodiesterases-Towards a Tailor-Made Approach in Multiple Sclerosis Treatment | SCHEPERS, Melissa; TIANE, Assia; PAES, Dean; SANCHEZ, Selien; ROMBAUT, Ben; PICCART, Elisabeth; Rutten, Bart P. F.; BRONE, Bert; HELLINGS, Niels; Prickaerts, Jos; VANMIERLO, Tim | Journal Contribution | A1 |
| 40 | 2018 | Oncostatin M-induced astrocytic TIMP-1 enables remyelination | HOUBEN, Evelien; JANSSENS, Kim; LAMBRICHTS, Ivo; Baekelandt, V.; SCHEPERS, Melissa; VANMIERLO, Tim; SLAETS, Leen; BROUX, Bieke; HELLINGS, Niels | Journal Contribution | M |
| 41 | 2018 | Roflumilast promotes memory recovery and attenuates white matter injury in aged rats subjected to chronic cerebral hypoperfusion | Santiago, Amanda; Soares, Ligia Mendes; SCHEPERS, Melissa; Milani, Humberto; VANMIERLO, Tim; Prickaerts, Jos; Weffort de Oliveira, Rubia M. | Journal Contribution | A1 |
| 42 | 2017 | The phosphodiesterase 4 (PDE4) inhibitor roflumilast improves remyelination in a mouse model for multiple sclerosis | SCHEPERS, Melissa; MAILLEUX, Jo; BOGIE, Jeroen; van Goethem, N.; HELLINGS, Niels; HENDRIKS, Jerome; Prickaerts, J.; VANMIERLO, Tim | Journal Contribution | M |
| 43 | 2017 | Early-postnatal iron deficiency impacts plasticity in the dorsal and ventral hippocampus in piglets | NELISSEN, Ellis; DE VRY, Jochen; Antonides, Alexandra; PAES, Dean; SCHEPERS, Melissa; van der Staay, Franz Josef; Prickaerts, Jos; VANMIERLO, Tim | Journal Contribution | A1 |
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