Please use this identifier to cite or link to this item:
http://hdl.handle.net/1942/28470
Title: | The impact of different types of exercise training on peripheral blood BDNF concentrations in older adults: A meta-analysis. | Other Titles: | De impact van verschillende types oefenprogramma's op de BDNF concentraties in het bloed bij ouderen: Een meta-analyse | Authors: | MARINUS, Nastasia HANSEN, Dominique FEYS, Peter MEESEN, Raf TIMMERMANS, Annick SPILDOOREN, Joke |
Issue Date: | 2019 | Source: | 42ste WINTER MEETING 2019, Oostende, 22-23 February 2019 | Abstract: | Objectives Alzheimer’s disease is associated with atrophy of the brain volume. Brain-derived neurotrophic factor (BDNF), a neurotrophin highly expressed in the hippocampus, has a protective effect on neuronal survival and maintenance in adulthood. Therefore, it plays an important role in preservation of brain function and size. The goal of this meta-analysis was to analyse the impact of aerobic and/or strength exercise training on BDNF concentrations in older adults (≥60 years). Methods This meta-analysis was completed in accordance with the PRISMA protocol. Inclusion criteria were: (i) studies with subjects (men and women) ≥ 60 years (ii) participation in a single exercise bout or an exercise program with (iii) measurements of blood BDNF; (iv) a comparison between (a) an intervention group and a control group or (b) two intervention groups, or (c) pre and post measurements of an exercise intervention without a control group. Studies with specific interest in known comorbidities such as diabetes, chronic pulmonary/cardiovascular diseases, musculoskeletal injuries or brain diseases affecting the peripheral and/or central nervous system, except for dementia, were excluded. Results Blood BDNF concentrations increased significantly in the exercise versus control group, both after a single exercise bout (Z=2.21, P=0.03) as well as after an exercise intervention (Z=4.72, P<0.00001). However, the increase in BDNF was significant only after strength training (Z=2.94, P=0.003) and combined training (Z=3.03, P=0.002) but not after aerobic exercise training (Z=0.82, P=0.41). Conclusions To increase blood BDNF concentrations in older adults, strength training and combined aerobic/strength training are preferred. | Document URI: | http://hdl.handle.net/1942/28470 | Category: | C2 | Type: | Conference Material |
Appears in Collections: | Research publications |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Abstract.docx | Conference material | 13.72 kB | Microsoft Word | View/Open |
Page view(s)
40
checked on May 25, 2022
Download(s)
10
checked on May 25, 2022
Google ScholarTM
Check
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.